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Apeldoorn, Netherlands

Haane D.Y.P.,Zuyderland Medical Center Heerlen | Plaum A.,Zuyderland Medical Center Heerlen | Plaum A.,Maastricht University | Koehler P.J.,Zuyderland Medical Center Heerlen | Houben M.P.W.A.,Zuyderland Medical Center Heerlen
Journal of Headache and Pain | Year: 2016

Background: The exact pathophysiology of cluster headache is unclear. We examined the influence of interneurons on the trigemino-facial reflex arch and the effect of oxygen, by using the nociception specific blink reflex parameters. Findings: There is no significant effect of oxygen, immediately and over time, on the nociception specific blink reflex parameters in ten male patients during the active phase of cluster headache, outside attacks. Also, there is no significant difference between the symptomatic and asymptomatic side. None of the subjects experienced a cluster headache attack during study participation. We therefore present the collected data as reference values of nociception specific trigeminal stimulation and the effect of oxygen on nociception specific blink reflex parameters. Conclusion: The nociception specific blink reflex seems not a suitable instrument for exploring the pathophysiology of cluster headache. © 2016, Haane et al. Source

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