Zibo Mining Group Co.

Zibo, China

Zibo Mining Group Co.

Zibo, China
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Zhang Z.,Liaoning Medical University | Zheng W.,Zibo Mining Group Co. | Xie H.,General Hospital of Shenyang Military Command | Chai R.,General Hospital of Shenyang Military Command | And 3 more authors.
Journal of Translational Medicine | Year: 2017

Background: Large numbers of CD8+ T cells were observed in atopic dermatitis (AD) skin, and monocytes from AD patients showed increased prostaglandin E2 production. However, little is known about the expression of substance P (SP) and its receptor NK1R in blood leukocytes of patients with AD. Objective: To explore the expression of SP and NK1R in leukocytes of AD and the influence of allergens on SP and NK1R expression. Methods: The expression levels of SP and NK1R in patients with AD were examined by flow cytometry, ELISA and a mouse AD model. Results: The plasma SP level was 4.9-fold higher in patients with AD than in HC subjects. Both the percentage of SP expression in the population and mean fluorescence intensity (MFI) of SP expression were elevated in CD8+ T cells in the blood of AD patients. However, both the CD14+NK1R+ population and MFI of NK1R expression on CD14+ cells were enhanced in the blood of AD patients. Allergens ASWE, HDME and PPE failed to up-regulate SP expression in CD8+ T cells. However, allergens ASWE and HDME both enhanced NK1R expression on CD14+ blood leukocytes regardless of AD or HC subjects. OVA-sensitized AD mice showed an elevated proportion and MFI of SP-expressing CD8+ T cells in the blood, which agrees with the SP expression situation in human AD blood. Injection of SP into mouse skin did not up-regulate NK1R expression on monocytes. Conclusions: An elevated plasma SP level, up-regulated expression of SP and NK1R indicate that the SP/NK1R complex is important in the development of AD. Therefore, SP and NK1R antagonist or blocker agents may help to treat patients with AD. Trial registration Registration number: ChiCTR-BOC-16010279; Registration date: Dec., 28, 2016; retrospectively registered. © 2017 The Author(s).


Chengxiang Z.,Zibo Mining Group Co.
Advanced Materials Research | Year: 2012

Mine solid waste is the great potential resource, but unreasonable resource development leads to the loss of solid waste and then does harm to environment. There are many ways of environmental management and comprehensive utilization of mine solid waste; recover useful elements, produce building materials, secondary energy recovery, fill the mine pit and collapse pit, paving, etc. However, many problems exist such as backward technology, lack of market competition due to low value-added products, government support which remains to be strengthened, less awareness of reasonable development of resources and effective environment protection, backward laws and regulations. Based on these problems, some relevant proposes were put forward. © (2012) Trans Tech Publications, Switzerland.


Zhang X.-G.,Shandong University of Science and Technology | Guo W.-J.,Shandong University of Science and Technology | Wang H.,Zibo Mining Group Co. | Li Y.-Y.,Shandong University of Science and Technology | Cao Z.,Zibo Mining Group Co.
Meitan Xuebao/Journal of the China Coal Society | Year: 2012

The pipeline pressure pre-alarm system was successfully developed by the KJ216 coal mine roof online monitoring system, self-developed obstruction unloading valve using hydraulic pressure principle and MPM480 piezoresistive pressure sensor, and accomplished pipeline pressured online monitoring and obstruction early pre-alarm. Monitoring data shows that it is possible to realize the long length pipeline safe transportatin by using the RS485 transmission of monitoring branch, master station, and the optical fiber transmission of master station and surface server and the pressure data renovation in a pumping(4.5 seconds), and the obstruction unloading valve.


Chen S.-J.,Shandong University of Science and Technology | Chen S.-J.,CAS Wuhan Institute of Rock and Soil Mechanics | Guo W.-J.,Shandong University of Science and Technology | Zhou H.,CAS Wuhan Institute of Rock and Soil Mechanics | Wen G.-H.,Zibo Mining Group Co.
Meitan Xuebao/Journal of the China Coal Society | Year: 2011

Space-time structure model and movement law of overburden were researched during strip pillar mining backfill with cream-body, taking 2351 backfilling face for an example. The results show that as the face advances, overburden strata are gradually transformed from the "C" type space structure into articulated rock beam with unequal height supports. The immediate roof of working face is the main roof; the first weighting interval is 33.6 m, and the periodic weighting length respectively are 18.3, 8.8, 13.7 and 9.0 m for the last four times. The overburden gravity mainly acted on coal wall in front of face and backfill paste, which had little effect on roof advance stress, and the influence scope is less than 15 m. In current technology conditions of face 2351, the reasonably maximal roof control distance is 8.8 m, the reasonable working resistance of support backfilling is 27 MPa, and the support setting load is 21 MPa.


Lin D.,University of Jinan | Wang C.,Zibo Mining Group Co. | Dong F.,Zibo Mining Group Co. | Lou S.,CAS Lanzhou Institute of Chemical Physics | Shou C.,University of Jinan
Advanced Materials Research | Year: 2011

Four kinds of polymer emulsions were coated on the surface of coal pitch carbon fiber using atomized flow static coating method. The surface morphology of the carbon fiber after modification was analyzed by fluorescence microscope.The tensile strength of coated carbon fiber in the cement mortar and the mechanical property of the coated carbon fiber reinforced concrete were tested. The results showed that all the polymer emulsions were coated successfully on the surface of carbon fiber. The tensile strength of the coated carbon fiber in the cement mortar increased obviously, specially for the carbon fiber coated by meta chloride copolymer emulsion, whose tensile strength improved by 61%. The tensile strength of the coated carbon fiber reinforced concrete increased by 11%, the fracture energy increased by 47% and the max crack width increased by 18.5% when the content of the carbon fiber coated by meta chloride copolymer was 1.7 kg/m3. © (2011) Trans Tech Publications, Switzerland.


Yu Z.,Shandong University of Technology | Liu X.,Zibo Mining Group Co.
Advanced Materials Research | Year: 2012

USB movable storage devices have been bringing significant convenience for data interchange among computers while chances of invalid copy and sensitive data leakage are exposed. In order to decrease the leakage possibility of confidential information, unilateral control takes effect in USB device. This paper introduces how to realize the unilateral control of USB device and elaborates the key technique thereof. © (2012) Trans Tech Publications, Switzerland.


Zhu S.,China University of Mining and Technology | Song S.,Zibo Mining Group Co. | Sun Q.,China University of Mining and Technology | Yan B.,China University of Mining and Technology | Wang C.,Zibo Mining Group Co.
Yanshilixue Yu Gongcheng Xuebao/Chinese Journal of Rock Mechanics and Engineering | Year: 2014

In order to study the characteristics of interaction process between deep rock of lower coal seam floor and water in Jibei mining area, five different types of rocks are used for water stability test in laboratory by natural water and saturated salt water soaking. Through water stability test and conductivity measuring for 52 days, the results are drawn as follows. (1) The water stability of nature soaked rocks is good, and none of them have basic degradation according to phenomena and test results of 20 samples in dropping residue, superficial cranny, rock cracking, strength change, swelling and degradation. However, the samples have obvious degradation by wetting- drying cycle effect. (2) There are three phases to conductivity increasing range in natural water by normal condition and wetting-drying cycle effect, but the conductivities of same sample under different conditions show big difference in increasing over time. The conductivity in wetting-drying cycle effect is obviously larger. (3) It is positive relevance between rock conductivity and decreasing rate of mass. The study results provide references for micro-mechanism study of deterioration for rocks under water-rock interaction in the deep coal mining.


Wan C.-Y.,Zibo Mining Group Co.
Chinese Journal of Cancer Prevention and Treatment | Year: 2011

OBJECTIVE: To investigate the diagnostic value of serum tumor markers for pneumoconiosis complicated with lung cancer. METHODS: The serum tumor markers Cyfra21-1, NSE, CEA and CA125 were measured with electrochemistry iluminescence in 98 cases of pneumoconiosis complicated with lung cancer, 151 cases of pneumoconiosis and 252 healthy coal miners. RESULTS: All the 4 tumor markers in lung cancer patients were significantly higher than that in pneumoconiosis and healthy controls (P<0.001). The levels of CEA and CA125 in adenocarcinoma, Cyfra21-1 in squamous carcinoma, NSE in small cell lung cancer were higher than other pathological types of lung cancer statistically (P<0.001). The accuracy of single marker to discriminate complicated with lung cancer and pneumoconiosis was 81.1% (202/249), 71.1% (177/249), 71.5% (178/249), 74.7% (186/249), respectively. Combined detection was 87.6% (218/249). CONCLUSION: The combined detection of Cyfra21-1, NSE, CEA, and CA125 is useful for differential diagnosis of pneumoconiosis complicated with lung cancer, and helpful to judge pathological types of lung cancer.

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