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Qiu N.-C.,Shanghai University | Liu M.-E.,Zhengjiang University | Wang B.,Shanghai University | Song X.,Shanghai University | And 5 more authors.
Journal of Gastrointestinal Surgery | Year: 2014

Objectives: The purpose of this study is to investigate the impact of the hepatic branch of the vagus and Roux-en-Y gastric bypass (RYGB) on the level of fasting and postprandial serum glucagon-like peptide-1 (GLP-1) in type 2 diabetic mellitus rats. Methods: Randomized block design, factorial experiment. Forty-five type 2 diabetic rats were divided into four groups: sham operation (S, n = 10) and sham operation with the hepatic branch of the vagotomy (SV, n = 11), Roux-en-Y gastric bypass (RYGB, n = 12) and RYGB without preservation of the vagus (RYGBV, n = 12). Levels of fasting and postprandial serum GLP-1 30 min after 50 % glucose solution (2 g/kg) by gavage were determined before surgery and postoperatively at 1, 4, and 8 weeks. Interactions between RYGB and the common hepatic branch were also assessed. Results: Roux-en-Y gastric bypass surgery significantly increased the concentration of postprandial serum GLP-1 and maintained it at a higher level (P < 0.05). Preservation of vagus hepatic branch only increased the concentration of postprandial serum GLP-1 at the initial stage (P < 0.05), which gradually weakened over time (P > 0.05). Both RYGB and vagotomy of the hepatic branch had no influence on fasting serum GLP-1 (P > 0.05). Conclusions: During RYGB surgery for the long-term treatment of T2DM, preservation of the hepatic branch of the vagus might have no impact on serum GLP-1 level. © 2014, The Society for Surgery of the Alimentary Tract. Source


Lin F.,Tongji University | Hong L.,Tongji University | Gu X.,Tongji University | Wang X.,Tongji University | Jin X.,Zhengjiang University
Construction and Building Materials | Year: 2012

The mechanical behaviour of cast-in situ reinforced concrete slabs with control joints is presented in this study. As an effective cracking control technique, setting joints into concrete slabs may significantly curb crack initiation and development, but may impair the structural integrity and decrease the bearing capacity of the slabs. To develop a realistic understanding of their mechanical behaviours, eighteen cast-in situ reinforced concrete slabs were tested statically, with consideration of different reinforcement ratios and joint lengths and depths. The relationship between the applied load and the centre deflection of the slabs was established, and the ultimate loads were obtained. A finite element method based model was developed, verified and used for a parametric study. It was found that, compared to slabs without control joints, jointed slabs had smaller bearing capacities and stiffness. The reduction of the bearing capacity grew with the increase in the length of the control joints. The influences of the reinforcement ratio, joint depth and slab thickness, however, were insignificant. The verified model was also employed to predict the mechanical behaviour of slabs with control joints fully filled with cement mortar. It was found that, with the control joints filled, the bearing capacity and stiffness of the slabs could be improved significantly, with the bearing capacity almost equal to that of unjointed slabs. © 2011 Elsevier Ltd. All rights reserved. Source


Lin F.,Tongji University | Song X.B.,Tongji University | Gu X.L.,Tongji University | Li C.,Tongji University | Jin X.Y.,Zhengjiang University
Proceedings of the 12th International Conference on Engineering, Science, Construction, and Operations in Challenging Environments - Earth and Space 2010 | Year: 2010

Concrete cracks due to shrinkage, changes of temperature and humidity and other reasons may impair the structural integrity and durability of concrete structures. To relieve the tensile strains and prevent unexpected cracks, one strategy is to intentionally set joints (namely control joints) at appropriate locations within the concrete members. In this paper, the validity and the major influencing factors of the control joints were studied. Firstly, in total eighteen slabs, including sixteen with control joints and the other two without control joints, were constructed and tested. Different concrete mix proportions, joint locations and depths, as well as the reinforcement ratios were considered. The concrete slabs were tested for 9 months with the complete process of the initiation and development of the concrete cracks in the slabs recorded. Secondly, for the purpose of numerical analysis, material properties of concrete were tested, using which numerical simulation and parametric study were conducted. It was found that the initiation and development of cracks in concrete slabs may be simulated by means of numerical modeling techniques. Cracks in concrete slabs can be to a large extent effectively regulated and the random occurrence of cracks can be prevented. Finally, the generated knowledge and the modeling technology were applied into a real project with tight restrictions on concrete cracks. By properly setting control joints according to the numerical simulation results the cracks were well controlled. © 2010 ASCE. Source


Kang Y.,State Oceanic Administration | Kang Y.,Zhengjiang University | Pan D.,State Oceanic Administration | He X.,State Oceanic Administration | And 2 more authors.
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2010

The ocean color remote sensing metadata describes the content, quality, condition, and other characteristics of ocean color remote sensing data. Paper presents a metadata standard draft based on XML, and gives the details of main ocean color remote sensing metadata XML elements. The ocean color remote sensing data platform-sharing is in developments as a part of the digital ocean system, on this basis, the ocean color remote sensing metadata directory service system based on web service is put forward, which aims to store and manage the ocean color remote sensing metadata effectively. The metadata of the ocean color remote sensing data become the most important event for the ocean color remote sensing information more retrieved and used. © 2010 SPIE. Source


Mao H.,Rochester Institute of Technology | Wang L.,Rochester Institute of Technology | Wong K.C.L.,French Institute for Research in Computer Science and Automation | Liu H.,Zhengjiang University | Shi P.,Rochester Institute of Technology
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2012

Heart is an electromechanical coupled organ, thus it is important to integrate electrical and mechanical functions when building a computational model of the heart. The existing models either treat electrical and mechanical functions separately, or follow a so-called "one-way" electromechanical coupling. However, electrical and mechanical functions of the heart are depended on each other, and realistic simulation results can only be achieved when such coupled relationship is considered. In this paper, we propose a generic model to simulate electromechanics of the heart that takes both electromechanical coupling and mechanoelectrical feedback into account. The model contains four components: cardiac electrophysiological model, electromechanical coupling, cardiac mechanics model and mechanoelectrical feedback. We report numerical simulations of a cube to provide an insight of the electromechanical coupled behavior of our model. Experiments have also been performed on a biventricular heart which present physiological plausible values, such as transmembrane potential (TMP) maps and strain maps. © 2012 Springer-Verlag. Source

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