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Medicine, China

Liang H.,Zhejiang University | Xu Z.,Zhejiang University | Zheng Z.,Hengdian Hospital of Zhejiang ProvinceZhejiang | Lou H.,Zhejiang UniversityZhejiang | Yue W.,Tianjin Huanhu Hospital
Orphanet Journal of Rare Diseases | Year: 2015

Background: Reversible cerebral vasoconstriction syndrome (RCVS) is an infrequent disease characterized by severe headaches with or without focal neurological deficits or seizures and a reversible vasoconstriction of cerebral arteries. The Orpha number for RCVS is ORPHA284388. However, RCVS triggered by blood transfusion is rare. Here we provided the clinical, neuroimaging and outcome data of patients diagnosed with RCVS resulting from red blood cells transfusion. Methods: We retrospectively identified 7 patients presenting with RCVS after red blood cells transfusion from January 2010 to May 2014. The information on clinical features, neuroimaging and outcome were collected and analyzed. Results: All 7 patients were Chinese women, with a mean age of 42 years (38-46). All the patients had severe anemia (Hb level<6 g/dl) caused by primary menorrhagia due to uterine myoma (n=5) or end-stage renal disease (n=2) and severe anemia persisted for a average period of 4 months (2-6). Each patient received packed red blood cells transfusion (average: 1580 ml) over a period of 2-5 days. Blood transfusion increased the hemoglobin level by at least 4.5 g/dL from baseline. The neurological symptoms appeared a mean of 6.3 days (2-13) after the last blood transfusion. Headache was the most frequent symptom and seizure, transient or persistent neurological disorders were observed. Neuroimaging showed cortical subarachnoid hemorrhage (n=2), focal intracerebral hemorrhage (n=2), localized brain edema (n=3), cerebral infarction (n=1), and posterior reversible encephalopathy syndrome (n=2). Cerebral vasoconstrictions were demonstrated by magnetic resonance angiography or cerebral angiography. Arterial constriction reversed in all patients within 1 to 3 months of follow-up after disease onset and no relapse was observed up to a mean of 17.1±4.8 months of follow-up. Conclusions: RCVS is a rare complication as a result of blood transfusion in patients with chronic severe anemia and should be considered in patients who show severe headache or neurologic deficits after transfusion. © 2015 Liang et al.; licensee BioMed Central. Source


Zhu H.Z.,Zhejiang UniversityZhejiang | Wu Z.,Shanxi University of Finance and Economics
Applied Mechanics and Materials | Year: 2014

With the development of global economic "integration" and "regionalization", it promoted the pace of changes of information technology and the market environment. The current companies attach great importance to the long-term business development strategic and coupled with resource constraints and increased competition, especially under the IT technical support environment. The companies begin to think about selecting ERP supply chain management, encouraging themselves to raise the whole level of integrated management and maximize expand business scope and finally improve the economic efficiency of the enterprises. © (2014) Trans Tech Publications, Switzerland. Source


Waygood E.O.D.,Laval University | Sun Y.,Zhejiang UniversityZhejiang | Letarte L.,Laval University
International Journal of Environmental Research and Public Health | Year: 2015

Active travel can contribute to physical activity achieved over a day. Previous studies have examined active travel associated with trips in various western countries, but few studies have examined this question for the Asian context. Japan has high levels of cycling, walking and public transport, similar to The Netherlands. Most studies have focused either on children or on adults separately, however, having children in a household will change the travel needs and wants of that household. Thus, here a household lifecycle stage approach is applied. Further, unlike many previous studies, the active travel related to public transport is included. Lastly, further to examining whether the built environment has an influence on the accumulation of active travel minutes, a binary logistic regression examines the built environment’s influence on the World Health Organization’s recommendations of physical activity. The findings suggest that there is a clear distinction between the urbanized centers and the surrounding towns and unurbanized areas. Further, active travel related to public transport trips is larger than pure walking trips. Females and children are more likely to achieve the WHO recommendations. Finally, car ownership is a strong negative influence. © 2015 by the authors; licensee MDPI, Basel, Switzerland. Source


Wang P.,Wenzhou University | Shi L.,Zhejiang UniversityZhejiang | Wang J.,Wenzhou University | Liu K.,City University of Hong Kong
Yantu Lixue/Rock and Soil Mechanics | Year: 2014

A model consisting of three-dimensional (3D) layered saturated ground and absorbing boundary applied at the bottom was established in this paper. By introducing the Fourier and orthogonal transformations, Biot's equations for the saturated soil are generated into equations governing Love and Rayleigh modes. By dividing the ground into several thin layer elements along the vertical direction and introducing linear interpolation function for the elemental displacement fields, the equations governing Love and Rayleigh modes for a single thin layer element are derived and then assembled to obtain global modal equations. After solving the homogenous global modal equations, the eigenvalues and corresponding eigenvectors of the saturated ground are obtained for Love and Rayleigh modes, separately. Eventually, the Green function for the 3D saturated ground is obtained for point loads by mode superposition method. Numerical results are presented to portray the evolution processes of eigenvalues of Love and Rayleigh modes with respect to the increasing excitation frequency and soil permeability. The Lamb problem of a homogeneous and layered saturated half-space is solved and compared with the numerical integration solutions given by Philippacopoulos. Through the comparisons, the obtained Green function is proven to be valid and accurate. Meanwhile, it does not require numerical integration with respect to Hankel functions and can take the soil stratification into consideration in a natural way, so as to improve the computation efficiency. ©, 2014, Academia Sinica. All right reserved. Source


Liu K.,New York University | Sun Z.,Zhejiang UniversityZhejiang | Wei T.,Zhejiang UniversityZhejiang
Clinical Medicine Insights: Cardiology | Year: 2015

Although most patients with Takotsubo cardiomyopathy (TTC) have benign clinical course and prognosis, TTC can induce acute heart failure and hemodynamic instability. TTC mimics the clinical features of acute anterior wall myocardial infarction (AMI). Bedside clinicians often have a diagnostic dilemma when cardiac catheterization and angiography are either contraindicated or can cause potential adverse consequences. Misdiagnosing TTC as AMI will lead to initiation of harmful pharmacological or device-based treatment, which worsens hemodynamic compromise. Therefore, under-standing and interpreting the unique pathophysiological and hemodynamic features of TTC in a better manner becomes crucial to guide effective clinical management of acute heart failure/cardiogenic shock during TTC. We review recent advances in echocardiographic diagnosis of TTC and its role in guid-ing bedside management of acute heart failure and cardiogenic shock, with specific focus on the interpretation of discrepant, but reciprocally dependent, left and right ventricular hemodynamics during acute stages of TTC. © the authors, publisher and licensee Libertas Academica Limited. Source

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