Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China

Hangzhou China, China

Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China

Hangzhou China, China
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Pan J.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | Wang M.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | Ye Z.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | Yu M.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | And 7 more authors.
Journal of Diabetes Investigation | Year: 2015

Aims/Introduction: The aim of the present study was to compare the cut-off values and prediction effect of different obesity indices by different definitions of metabolic syndrome (MetS) in Zhejiang Province of China. Materials and Methods: We carried out a cross-sectional survey of 10,100 individuals (age 40 years and older) in Jiashan, Zhejiang Province. Receiver operating characteristic analysis was used to examine discrimination and find optimal cut off values of waist circumference (WC), body mass index (BMI), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) to predict two or more non-adipose components of MetS by The National Cholesterol Education Program Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) definition modified by the Asia-Pacific region criteria, International Diabetes Federation definition for the Chinese population and Chinese Diabetes Society definitions of MetS. Results: The age-standardized prevalence of MetS was 23.78% vs 28.76% vs 19.37% by The National Cholesterol Education Program Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III), International Diabetes Federation and Chinese Diabetes Society definitions, respectively. Cut-off values of BMI were approximately 24 kg/m2 both in men and women by three definitions; the average cut-off values of WC, WHR and WHtR were 83 cm in men vs 81 cm in women, 0.89 in men vs 0.86 in women and 0.50 in men vs 0.51 in women, respectively. The area under receiver operating characteristic curve of BMI was larger than WC both in men and women (P < 0.05); in women, the area under receiver operating characteristic curve of WHtR was larger than WC, and WHR was smaller. Conclusions: MetS is prevalent in Zhejiang Province of China, especially in the female population. BMI and WHtR might be more useful than WC and WHR for predicting two or more non-adipose components of MetS. © 2015 The Authors. Journal of Diabetes Investigation published by Asian Association of the Study of Diabetes (AASD) and Wiley Publishing Asia Pty Ltd.


Wu P.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | Cai C.,Zhejiang University of Science and Technology | Yang D.,The National Center for Food Safety Risk Assessment Beijing China | Wang L.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | And 4 more authors.
Journal of Separation Science | Year: 2015

A detection method for 19 kinds of phthalic acid ester compounds analyzed by n-hexane/ether/acetonitrile 1:7:8 v/v/v mixed solvent extraction, quick, easy, cheap, effective, rugged, and safe purification and internal standard method of quantitative gas chromatography with mass spectrometry was established. This method can effectively remove interfering materials, such as lipids, fatty acids, and pigments, from dairy products. The 19 kinds of phthalic acid ester compounds were within a 0.025-0.2 mg/kg range, the recovery rate was 65.2-125.7%, relative standard deviation was 7.9-15.4% (n = 6), and the limit of detection was 0.005-0.02 mg/kg. Concentrations of the 19 kinds of phthalic acid ester compounds ranged between 0.01 and 0.12 mg/kg in ten dairy materials and 20 dairy products. The established method is simple, rapid, accurate, and highly sensitive. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Xu X.-m.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | Yu X.-w.,Zhoushan Municipal Center for Disease Control and Prevention Zhoushan China | Lu M.,Agilent Technologies | Huang B.-f.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China | Ren Y.-p.,Zhejiang Provincial Center for Disease Control and Prevention Hangzhou China
Journal of Separation Science | Year: 2015

Tetrodotoxin is a marine biotoxin with high acute toxicity. The levels in cooked seafood will help us to assess its intake in humans and may help assess the risk of toxicity. However, heavy matrices hinder the direct quantitation of tetrodotoxin. A quantitative method of measuring tetrodotoxin in cooked seafood using liquid chromatography with triple quadrupole mass spectrometry was established in this study. Tetrodotoxin was extracted from the sample matrix using 2% formic acid in methanol and cleaned using a cation exchange cartridge. The cleanup conditions were optimized. The matrix effects were determined using the postextraction spiking method and by comparing the slope of the linear regression equation in sample matrix to that in solvent. The limit of detection in the sample matrix was 5 μg/kg and the limit of quantification was 10 μg/kg. The mean recoveries at three spiking levels were 66.9-89.2% with relative standard deviations of 5.0-10.8% (n = 6) in five different matrices. Tetrodotoxin was found at concentrations of 26.1-2462 μg/kg in nine of 83 cooked seafoods tested in this study. Eight analogs of Tetrodotoxin were detected in the samples studied. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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