Paulun A.,Klinik fur Kinder und Jugendli che |
Losch H.,Klinik fur Kinder und Jugendli che |
Simic-Schleicher G.,Zentrum fur padiatrische Endokrinologie |
Renneberg A.,Klinik fur Kinder und Jugendli che
Monatsschrift fur Kinderheilkunde | Year: 2012
The case of a 9-year-old girl with relapsing cephalgia, weight loss and arterial hypertension due to hyperthyroidism is presented. Clinical findings suggested Graves' disease, but TRAbs (TSH receptor antibodies) were negative at first. They were only detected after the serum had been diluted because the high concentration of TRAbs in the serum led to a false-negative result due to the high-dose hook effect. © Springer-Verlag 2012.