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Zaporizhia, Ukraine

Labenska I.B.,Zaporizhia State University | Shapoval G.A.,Ukrainian Academy of Sciences | Kruglyak O.S.,Ukrainian Academy of Sciences | Omeljanchik L.A.,Zaporizhia State University | And 2 more authors.
Ukrain'skyi Biokhimichnyi Zhurnal | Year: 2010

The influence of substituents in the sixth position of N-acyl derivatives of 2-methyl-4-mercaptoquinoline on hepatoprotective and antioxidant effect was investigated. It was also determined that alcoxy-derivatives show hepatoprotective, antiradical, antioxidant activity and can act as preventive antioxidants. Introduction of the ethoxy-group into the sixth position of azoheterocycle potentiates activity. Symbasis of intensities of hepatoprotective and antioxidant actions of the investigated compounds was proved.

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