Ylka S.,Kliniczny Dzial Otolaryngologii |
Kopczynski J.,Zaklad Patologii Nowotworow SCO |
Kdzierawski P.,Dzial Radioterapii SCO |
Zawadzki M.,Kliniczny Dzial Otolaryngologii
Otolaryngologia Polska | Year: 2011
Malignant nasopharygeal neoplasms are relatively rare. Anaplastic nasopharyngeal carcinoma is the most common and the most malignant one. In this paper, we present a case of 56-year old patient with high-grade leiomyosarcoma of nasopharynx. The final diagnosis was achieved by using immunohistochemical methods - SMA (+), Caldesmon (+/-), Desmin (+/-), bcl 2 (+/-), EMA (-), S-100 (-), CD 34 (-), MIB 1 - 70% cells. The patient was successfully treated with radical radiotherapy IMRT technique (total dose 7000 cGy in 7 weeks). Currently, the patient has no symptoms and signs of the disease (oncological follow-up; CT imaging, PET-CT). This case is the first nasopharyngeal leiomyosarcoma reported in Poland, and probably the second one in the world. © by Polskie Towarzystwo Otorynolaryngologów - Chirurgów Glowy i Szyi.