Yuvarajas College

Mysore, India

Yuvarajas College

Mysore, India

Time filter

Source Type

Fazal E.,Yuvarajas College | Kaur M.,University of Mysore | Sudha B.S.,Yuvarajas College | Nagarajan S.,Indian Central Food Technological Research Institute | Jasinski J.P.,Keene State College
Acta Crystallographica Section E: Structure Reports Online | Year: 2013

In the title compound, C16H10ClNO2, the dihedral angle between the quinoline ring system and the benzene ring is 14.7 (5)°. The carboxylate group is twisted from the mean planes of the quinoline ring system and the benzene ring by 17.7 (5) and 32.1 (4)°, respectively. In the crystal, inversion dimers are formed with the molecules linked by pairs of weak C-H⋯O interactions arising from an activated aromatic C atom adjacent to the C-Cl bond, generating R 22(14) loops.


Fazal E.,Yuvarajas College | Kaur M.,University of Mysore | Sudha B.S.,Yuvarajas College | Nagarajan S.,Indian Central Food Technological Research Institute | Jasinski J.P.,Keene State College
Acta Crystallographica Section E: Structure Reports Online | Year: 2013

In the title compound, C17H12ClNO2, the dihedral angle between the mean planes of the quinoline ring system and the benzene ring is 68.7 (7)°. The mean plane of the carboxylate group is twisted from the latter planes by 14.0 (1) and 80.2 (4)°, respectively. In the crystal, weak C-H⋯O interactions are observed, forming chains along [001]. In addition, π-π stacking interactions [centroid-centroid distances = 3.8343 (13) and 3.7372 (13)Å] occur. No classical hydrogen bonds were observed.


Fazal E.,Yuvarajas College | Jasinski J.P.,Keene State College | Krauss S.T.,Keene State College | Sudha B.S.,Yuvarajas College | Yathirajan H.S.,University of Mysore
Acta Crystallographica Section E: Structure Reports Online | Year: 2012

In the title compound, C17H13NO2, two molecules crystallize in the asymmetric unit. The dihedral angle between the mean planes of the quinoline and benzene rings are 78.3(4) and 88.2(3)°. The carboxylate group is twisted slightly from the quinoline ring by 7.1(2) and 13.3(4)°, respectively. In the crystal, weak C-H⋯O interactions are observed. Further stabilization is provided by weak π-π stacking interactions, with centroid-centroid distances of 3.564(9)/3.689(2) and 3.830(1)/3.896(5)Å, respectively.


Fazal E.,Yuvarajas College | Jasinski J.P.,Keene State College | Anderson B.J.,Keene State College | Sudha B.S.,Yuvarajas College | Nagarajan S.,Indian Central Food Technological Research Institute
Acta Crystallographica Section E: Structure Reports Online | Year: 2014

In the title compound, C20H25NO2, the cyclohexyl ring adopts a slightly disordered chair conformation. The dihedral angle between the mean planes of the quinoline ring and the carboxylate group is 22.2(6)°. In the crystal, weak C-H⋯N interactions make chains along [010].


Fazal E.,Yuvarajas College | Kaur M.,University of Mysore | Jasinski J.P.,Keene State College | Nagarajan S.,Indian Central Food Technological Research Institute | Sudha B.S.,Yuvarajas College
Acta Crystallographica Section E: Structure Reports Online | Year: 2014

In the title compound, C18H15NO2, the dihedral angle between the mean planes of the quinoline ring system and the phenyl ring is 78.8(1)°. The mean plane of the carboxylate group is twisted from the mean planes of the quinoline ring system and phenyl ring by 1.5(9) and 77.6(4)°, respectively. In the crystal, molecules are linked by weak C - HO interactions, generating C(8) chains along [001]. Weak π-π stacking interactions are also observed [centroid-centroid separation = 3.6238(12)Å]. © Fazal et al. 2014.


PubMed | Fatima Mata National College, Indian Central Food Technological Research Institute, Dr Hari Singh Gour University, Yuvarajas College and 2 more.
Type: | Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy | Year: 2015

FT-IR and FT-Raman spectra of 4-chlorophenyl quinoline-2-carboxylate were recorded and analyzed. The vibrational wavenumbers were computed using DFT quantum chemical calculations. The data obtained from wavenumber calculations are used to assign vibrational bands obtained experimentally. Potential energy distribution was done using GAR2PED program. The geometrical parameters obtained theoretically are in agreement with the XRD data. NBO analysis, HOMO-LUMO, first hyperpolarizability and molecular electrostatic potential results are also reported. The calculated hyperpolarizability of the title compound is 77.53 times that of the standard NLO material urea and the title compound and its derivatives are attractive object for future studies of nonlinear optical properties. Molecular docking results suggest that the compound might exhibit inhibitory activity against GPb.


PubMed | Fatima Mata National College, Indian Central Food Technological Research Institute, Dr Hari Singh Gour University, Yuvarajas College and 2 more.
Type: | Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy | Year: 2015

FT-IR and FT-Raman spectra of 4-Methylphenylquinoline-2-carboxylate were recorded and analyzed. The structure of the molecule has been optimized and structural characteristics have been determined by density functional theory. The geometrical parameters (DFT) are in agreement with the XRD results. HOMO and LUMO and other chemical properties are reported. Nonlinear optical properties are also reported. A detailed molecular picture of the title compound and its interactions were obtained from NBO analysis. The negative (red and yellow) regions of the MEP are related to electrophilic reactivity and the positive (blue) regions to nucleophilic reactivity, as shown in the MEP plot and the carbonyl group and the phenyl rings are observed as electrophilic. PASS analysis predicts that the 4-Methylphenylquinoline-2-carboxylate might exhibit anti-diabetic activity. Molecular docking results suggest that the compound might exhibit inhibitory activity against GPb.


PubMed | Yuvarajas College, Indian Central Food Technological Research Institute and Keene State College
Type: Journal Article | Journal: Acta crystallographica. Section E, Structure reports online | Year: 2014

In the title compound, C20H25NO2, the cyclo-hexyl ring adopts a slightly disordered chair conformation. The dihedral angle between the mean planes of the quinoline ring and the carboxyl-ate group is 22.2(6). In the crystal, weak C-HN inter-actions make chains along [010].


PubMed | Yuvarajas College, Manipal University India, R. L. Fine Chemicals Ltd. Yelahanka and Karnatak University
Type: | Journal: European journal of medicinal chemistry | Year: 2016

A series of 6-chloro-5-(2-substituted-ethyl)-1,3-dihydro-2H-indol-2-ones (3a-h) and 6-chloro-5-(2-chloroethyl)-3-(alkyl/aryl-2-ylidene)indolin-2-ones (5i-x) were synthesized. Compounds 3a-e, 5i-l and 5q-r were selected by NIH, USA for invitro anti-proliferative screening. Based on the impressive growth inhibitory (GI %) effect by the compounds 3a-b and 3e which showed growth inhibition in the range 1.22-76.30%, 2.85-76.03% and 10.98-82.05% respectively at 10(-5) concentration, these compounds were further analyzed for anti-proliferative activity at 5 dose concentration and genotoxicity.


Khairy H.,University of Mysore | Janardhana M.R.,Yuvarajas College
Nature Environment and Pollution Technology | Year: 2012

Present study is an attempt to understand the hydrochemical characteristics of groundwater in Amol- Ghaemshahr region, Mazandaran province in North Iran. Groundwater samples were randomly collected from 77 wells in Amol-Ghaemshahr plain having different depths, varying from 2.4 m to 198 m. The physicochemical parameters such as pH, electrical conductivity (EC) and total dissolved solids (TDS) were measured in addition to major cation and anion concentrations. The abundance of major ions is as follows: Ca2+ > Na+ > Mg2+ > K+ and HCO3 - > Cl- >SO 4 2- > NO3 -. Thematic maps pertaining to pH, TDS, EC, Cl-, NO3 -, SO4 2- and Na + were presented in Geographical Information System (GIS) based maps. Different classes in thematic maps were categorized as desirable, permissible and unpermissible based on WHO standards for drinking purposes. The chemistry of water samples from coastal aquifer was interpreted by using classical Piper diagrams. The study indicates that Ca-Mg-HCO3 and Ca-Mg-Cl are the dominant hydrochemical facies followed by Na-Cl and Ca-Mg-SO4 facies. Gibb's plot reveals that the mechanisms responsible for controlling chemical composition of the groundwater are both rock-water interaction and evaporation.

Loading Yuvarajas College collaborators
Loading Yuvarajas College collaborators