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Chen T.,Yulin Orthopedic Hospital | Jia S.-Q.,Yulin Orthopedic Hospital | Chen W.,Yulin Orthopedic Hospital | Li P.-Q.,Yulin Orthopedic Hospital
Chinese Journal of Tissue Engineering Research | Year: 2013

BACKGROUND: Abnormality of spnio-pelvic parameters is closely related to the occurrence and progress of lumbar spondylolisthesis. OBJECTIVE: To explore the change and clinical significance of spino-pelvic parameters in lumbar spondylolisthesis patients after internal fixation. METHODS: A retrospective analysis was conducted on 60 patients with lumbar spondylolisthesis undergoing posterior lumbar interbody fusion and internal fixation. The pre-and post-operative lumbar lordosis, pelvic projectional angle, sacralslope angle, pelvic tilting angle, sagittal balance, slip degree, slip angle and height of intervertebral disc were measured on X-ray film. These parameters were analyzed using t-test between pre- and post-operation. Linear correlations between these parameters were analyzed. RESULTS AND CONCLUSION: There were significant differences between pre- and post-operative slip degree, slip angle, height of intervertebral disc, lumbar lordosis, pelvic tilting, sacral slope and sagittal balance (P < 0.01). The restoration of height of intervertebral disc showed significant correlation with the change of lumbar lordosis, pelvic tilting, sacral slope, slip degree and slip angle. The change of lumbar lordosis was significantly correlated with the change of slip angle, slip degree, pelvic tilting and sacral slope. It indicates that posterior lumbar interbody fusion and internal fixation can significantly improve the sacral slope, pelvic tilting, lumbar lordosis and sagittal balance of the patients with lumbar spondylolisthesis. Therefore, when treating lumbar spondylolisthesis patients with posterior lumbar interbody fusion and internal fixation, compensatory mode of pelvis with different pelvic projectional angles must be considered, and surgical surgeons should restore the height of intervertebral disc individually.

Luo S.,Yulin Orthopedic Hospital | Yang Y.,Yulin Orthopedic Hospital | Yang X.,Yulin Orthopedic Hospital | Li Z.,Yulin Orthopedic Hospital | And 4 more authors.
Chinese Journal of Clinical Oncology | Year: 2012

Objective: To explore the clinical effect of limb salvage treatment on pediatric Ewing's sarcoma in the femur shaft via neoadjuvant chemotherapy and vascularized fibular graft. Methods: Twenty patients with pediatric Ewing's sarcoma in the femur shaft were classified into Stage A or B-according to Enneking classification. The patients were treated via preoperative neoadjuvant chemotherapy, limb salvage surgery, and postoperative neoadjuvant chemotherapy. The postoperative chemotherapy was adjusted according to the tumor necrosis rate after surgery. Results: All patients were followed up for 6 months to 45 months (mean of 30 months). Seventeen out of the 20 patients survived without recurrence or distant metastasis until August 30, 2011. One patient developed pelvis metastasis and died of pulmonary embolism one year after surgery, and two patients died of pulmonary metastasis two years after surgery. The 3-year disease-free-survival rate was 85%. All patients were treated via limb salvage. The union between the fibula and the femur shaft was achieved within 8 weeks to 12 weeks after surgery. The results were evaluated using the Enneking evaluation system, which detected effective treatment in 20 patients. Conclusion: Neoadjuvant chemotherapy combined with vascularized fibular graft is one of the effective methods for the treatment of pediatric Ewing's sarcoma in the femur shaft.

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