Cuddapah, India
Cuddapah, India

Yogi Vemana University is a newly established University in Kadapa district with West Campus at Idupulapaya. Earlier, it was a part of Sri Venkateswara University, Tirupati. It is named after a great thinker, philosopher, and social reformer Yogi Vemana, the most celebrated Telugu poet and sage of all time.Late Dr. Y S Rajasekhara Reddy, the former Chief Minister of Andhra Pradesh donated his 312 acres of land to build West Campus. A modern concept school, which is called 21st Century Gurukul. The university is named after Yogi Vemana who is known for his philosophical teachings and practicing Achala Paripurna Raja Yoga. Children are taught his teachings and poems at school as part of regular syllabus and moral science at schools.This University was known earlier as Sri Venkateswara University PG Centre, Kadapa. This PG centre at Kadapa was established as a constituent institute of Sri Venkateswara University, Tirupati on 20 November 1977.It was upgraded as Yogi Vemana University by the Government of Andhra Pradesh through an Act of A.P. Legislative Assembly on 9 March 2006. It is located at Mittamedipalli village and Panchayat about 15 km from the Kadapa on the Kadapa-Pulivendla road. The campus is spread over 450 acres of land. Arjula Ramachandra Reddy, An Eminent Biologist, was the first vice-chancellor of Yogi Vemana University, Kadapa. The Yogi Vemana University, semi-residential in character, has unitary status and potential for phenomenal academic growth in the disciplines of Modern science and Technologies, Humanities and social science in the Years to come.C.P.Brown Library with rich collection of rare books, ancient documents and relics, situated in Kadapa is part of Yogi Vemana University providing research facilities in several disciplines.Yogi Vemana University has at present 15 departments offering courses at post graduate level in 17 disciplines in LanguagesPhysical and Bio-science, Human Resources Management, MBA & MCA and New science like Biotechnology, Bioinformatics, Geoinformatics and Earth science. The University has also introduced Five year integrated M.Sc. Courses in Earth science and Bioinformatics in the year 2007-08.Yogi Vemana University College of Engineering, Proddatur was established in 2008-2009 and renamed as YSR Engineering College of Yogi Vemana University in the year 2010. It offers six conventional disciplines of Civil, Computer Science, Electronics & Communications, Information Technology, Mechanical and Electrical & Electronics Engineering leading to the Degree of Bachelor of Engineering. Along with the above the College is offered a new course in "Metallurgical Engineering " from the ensuing academic year.Engineering campus: Wikipedia.


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Eswaramma S.,Yogi Vemana University | Rao K.S.V.K.,Yogi Vemana University
Carbohydrate Polymers | Year: 2017

The present study aims at preparation of dual responsive interpenetrating polymer network hydrogel microbeads from sodium alginate and functionally modified guar gum. Guar gum was modified by graft copolymerization using N-vinylcaprolactam, the maximum % grafting 123.2, obtained at different optimized conditions. The graft copolymer was blended with sodium alginate to form hydrogel microbeads by emulsion crosslinking method using glutaraldehyde as crosslinker. Zidovudine, an anti-HIV drug was encapsulated with 68% encapsulation efficiency. Fourier transform infrared spectroscopy, 1H nuclear magnetic resonance spectroscopy, scanning electron microscopy, differential scanning calorimetry and X-ray diffraction studies justified the grafting reaction, structure, morphology and polymer-drug interactions, respectively. Swelling studies ascertained that microbeads were potentially sensitive to both pH and temperature. In vitro release studies were investigated in pH 1.2 and 7.4, the release time enhanced up to 34 h in pH 7.4 at 37 °C. © 2016 Elsevier Ltd


Gokara M.,University of Hyderabad | Sudhamalla B.,University of Hyderabad | Amooru D.G.,Yogi Vemana University | Subramanyam R.,University of Hyderabad
PLoS ONE | Year: 2010

Background:Human serum albumin (HSA) is the most abundant protein in blood plasma, having high affinity binding sites for several endogenous and exogenous compounds. Trimethoxy flavone (TMF) is a naturally occurring flavone isolated from Andrographis viscosula and used in the treatment of dyspepsia, influenza, malaria, respiratory functions and as an astringent and antidote for poisonous stings of some insects. Methodology/Principal Findings:The main aim of the experiment was to examine the interaction between TMF and HSA at physiological conditions. Upon addition of TMF to HSA, the fluorescence emission was quenched and the binding constant of TMF with HSA was found to be KTMF = 1.0±0.01×103 M-1, which corresponds to -5.4 kcal M-1 of free energy. Micro-TOF Q mass spectrometry results showed a mass increase of from 66,513 Da (free HSA) to 66,823 Da (HAS +Drug), indicating the strong binding of TMF with HSA resulting in decrease of fluorescence. The HSA conformation was altered upon binding of TMF to HSA with decrease in α-helix and an increase in β-sheets and random coils suggesting partial unfolding of protein secondary structure. Molecular docking experiments found that TMF binds strongly with HSA at IIIA domain of hydrophobic pocket with hydrogen bond and hydrophobic interactions. Among which two hydrogen bonds are formed between O (19) of TMF to Arg 410, Tyr 411 and another one from O (7) of TMF to Asn 391, with bond distance of 2.1 Å, 3.6 Å and 2.6 Å, respectively. Conclusions/Significance: In view of the evidence presented, it is imperative to assign a greater role of HSA's as a carrier molecule for many drugs to understand the interactions of HSA with TMF will be pivotal in the design of new TMF-inspired drugs. © 2010 Gokara et al.


Philomina N.S.,Yogi Vemana University
Indian Journal of Biotechnology | Year: 2010

Plant regeneration through somatic embryogenesis has been developed in an economically important forest tree, Sapindus mukorossi Gaetin. Calli obtained by culturing young leaf explants on MS medium containing growth regulators, 2,4-D (6.7 μM) and Kn (9.0 μM), when subjected to reduced levels of 2,4-D (2.2μM)+Kn (4.6μM), produced numerous somatic embryos. Somatic embryos developed into complete plantlets on MS medium devoid of growth regulators. The regenerated plantlets were successfully established in the soil with 90% survival frequency after a few days of acclimatization.


Subramani P.A.,Yogi Vemana University | Narala V.R.,Yogi Vemana University
Natural Product Communications | Year: 2013

Nanoparticles are promising aids for drug delivery for previously challenging diseases, and many incurable ones. Curcumin (diferuloylmethane) is a pleiotropic molecule having various target molecules in the body. Despite its effects, curcumin-based drugs are not readily available in the market because of their low bioavailability. Although dietary intake and knowledge about the potential of curcumin are high in countries like India, studies indicate that the bioavailability problem still persists. However, administration of curcumin through inhalation has received little consideration. In this review we discuss the potential of curcumin, approaches made to overcome the bioavailability challenges, and novel approaches that could be applied in order to deliver curcumin in a pressurized metered dose inhaler (pMDI).


Praveen Kumar D.,Yogi Vemana University | Shankar M.V.,Yogi Vemana University | Mamatha Kumari M.,Yogi Vemana University | Sadanandam G.,Indian Institute of Chemical Technology | And 2 more authors.
Chemical Communications | Year: 2013

Solar light induced interfacial charge transfer of electrons from TiO 2 to CuO in a water-glycerol mixture produced 99823 μmol h -1 g-1 catalyst of hydrogen gas. The dispersed CuO/TiO2 photocatalyst in solution exhibited uni-directional electron flow and capture at the Schottky barrier facilitating charge separation and electron transfer resulting in enhanced H2 production performance. © 2013 The Royal Society of Chemistry.


Vali Pasha K.,Yogi Vemana University
Asian Journal of Pharmaceutical and Clinical Research | Year: 2012

Prolactin and Growth Hormone are anterior pituitary hormones having multiple physiological functions and number of neurotransmitters and neuropeptides are involved in their regulation. Plasma GH, prolactin and brain GABA levels were determined at 5 and 15 mins after thirdventricular injection of glutathione at doses of 15 or 30 μg in ovariectomized steroid-primed rats. Intraventricular glutathione significantly increased plasma growth hormone (GH) levels at 5 and 15 min after injection. A 15 μg dose of glutathione significantly decreased prolactin levels at 5 min after injection. A higher dose of glutathione (30 μg) however, significantly elevated plasma prolactin levels at 5 and 15 min after injection. Glutathione at a 30 μg dose caused a significant increase in hypothalamic GABA levels at 5 and 15 min after injection where as the same dose decreased GABA levels in the cerebral cortex. The release of GH and prolactin by higher dose of glutathione may be mediated through enhanced levels of GABA. These studies demonstrate a neuroendocrine role of glutathione.


Shanmugavelu B.,Pondicherry University | Venkatramu V.,Yogi Vemana University | Ravi Kanth Kumar V.V.,Pondicherry University
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | Year: 2014

Glasses with compositions of (100-x) (Bi2ZnOB2O 6) - x Nd2O3 (where x = 0.1, 0.3, 0.5, 1 and 2 mol%) were prepared by melt quenching method and characterized through optical absorption, emission and decay curve measurements. Optical absorption spectra have been analyzed using Judd-Ofelt theory. The emission spectra exhibit three peaks at 919, 1063 and 1337 nm corresponding to 4F3/2 to 4I9/2, 4I11/2 and 4I 13/2 transitions in the near infrared region. The emission intensity of the 4F3/2 to 4I11/2 transition increases with increase of Nd3+ concentration up to 1 mol% and then concentration quenching is observed for 2 mol% of Nd3+ concentration. The lifetimes for the 4F3/2 level are found to decrease with increase in Nd2O3 concentration in the glasses. The decay curves of the glass up to 0.3 mol% of Nd3+ exhibit single exponential nature and thereafter the curves become nonexponential nature (0.5, 1 and 2 mol%). The nonexponential curve has been fitted to the Inokuti-Hirayama model to understand the nature of energy transfer process. © 2013 Elsevier B.V. All rights reserved.


Mohan R.B.,Yogi Vemana University | Reddy N.C.G.,Yogi Vemana University
Synthetic Communications | Year: 2013

A simple and more convenient method has been developed for regioselective α-bromination of various aralkyl ketones with N-bromosuccinimide (NBS) in the presence of Montmorillonite K-10 catalyst in methanol at 60-65 °C. The present procedure offers advantages of short reaction time, simple workup, good yields of products and reusability of the catalyst for four times without loss of activity. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file. © 2013 Copyright Taylor and Francis Group, LLC.


Srinivasa Gowd S.,CSIR - Central Electrochemical Research Institute | Srinivasa Gowd S.,Yogi Vemana University | Ramakrishna Reddy M.,Yogi Vemana University | Govil P.K.,CSIR - Central Electrochemical Research Institute
Journal of Hazardous Materials | Year: 2010

Environmental geochemical studies were carried out in and around Jajmau (Kanpur) and Unnao industrial areas (80°15′-80°34′E longitude and 26°24′-26°35′N latitude), of Uttar Pradesh to find out the extent of chemical pollution in soil due to industrial waste. Jajmau and Unnao are prominent centers for leather processing clusters of tannery industries (about 450) along the banks of river Ganga, besides other industries. Geologically the study area is beset with alluvium of Quaternary age consisting of older alluvium of middle to upper Pleistocene and newer alluvium of Holocene. The climate of the study area is semi-arid type. Fifty-three soil samples were collected from Jajmau and Unnao industrial areas from top 15 cm layer of the soil and were analyzed for heavy metals by using Philips MagiX PRO-PW 2440 X-ray fluorescence spectrometer. The data reveals that the soil in the area is significantly contaminated with heavy metals such as chromium varies from 161.8 to 6227.8 mg/kg (average of 2652.3 mg/kg), Ba varies from 44.1 to 780.9 mg/kg (average of 295.7 mg/kg), Cu varies from 1.7 to 126.1 mg/kg (average of 42.9 mg/kg), Pb varies from 10.1 to 67.8 mg/kg (average of 38.3 mg/kg), Sr varies from 46.6 to 150.6 mg/kg (average of 105.3 mg/kg), V varies from 1.3 to 208.6 mg/kg (average of 54.4 mg/kg) and Zn varies from 43.5 to 687.6 mg/kg (average of 159.9 mg/kg). Soil contamination was assessed on the basis of geoaccumulation index, enrichment factor (EF), contamination factor and degree of contamination. Indiscriminate dumping of hazardous waste in the study area could be the main cause of the soil contamination, spreading by rainwater and wind. Distribution and correlation of heavy metals in soil along with possible remedial measures are discussed. © 2009 Elsevier B.V. All rights reserved.


Reddy L.V.A.,Yogi Vemana University | Reddy O.V.S.,Sri Venkateswara University
Food and Bioproducts Processing | Year: 2011

In this study mango juice fermentation at laboratory scale with controlled inoculation using selected yeast strain was performed (Saccharomyces cerevisiae 101). Effect of fermentation conditions (temperature, pH, SO 2 and aeration) on wine fermentation was evaluated based on yeast growth, duration, fermentation rate and volatile composition. The composition of the major volatile compounds with low boiling points was determined by gas chromatography under the different operating conditions of fermentation temperature (15-35 °C), pH (3.5-6.0), SO 2 (100-300 ppm) and aeration (initial dissolved O 2 and shaking at 30 rpm). Temperature had important effect on yeast growth and on the levels of volatile compounds. It was observed that the final concentrations of ethyl acetate and some of the higher alcohols decreased when fermentation temperature increased to 25 °C (35 mg/l at 15 °C and 27 mg/l at 25 °C). SO 2 stimulated the yeast growth up to certain level and in excess it inhibited the yeast metabolism. Ethanol concentration slightly increased with the addition of 100 ppm SO 2 (8.2 g/l) and decreased with increase in concentration of SO 2 (6.2 g/l in 300 ppm SO 2). Aeration by shaking increased the viable cell count (from 52 × 10 6 in the absence of oxygen to 98 × 10 6 in shaking at 30 rpm) but decreased the ethanol productivity (from 7.2 in initial dissolved O 2 to 6.5 g/l shaking at 30 rpm). With the results obtained it was concluded that the temperature (25 °C), pH (5), SO 2 (100 ppm) and must with initial oxygen were optimum for better quality of wine from mango fruits. The results of the present study considering the traditionally recognized preference for low alcoholic fermentation temperatures in wine making. © 2010 The Institution of Chemical Engineers.

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