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Cuddapah, India

Yogi Vemana University is a newly established University in Kadapa district with West Campus at Idupulapaya. Earlier, it was a part of Sri Venkateswara University, Tirupati. It is named after a great thinker, philosopher, and social reformer Yogi Vemana, the most celebrated Telugu poet and sage of all time.Late Dr. Y S Rajasekhara Reddy, the former Chief Minister of Andhra Pradesh donated his 312 acres of land to build West Campus. A modern concept school, which is called 21st Century Gurukul. The university is named after Yogi Vemana who is known for his philosophical teachings and practicing Achala Paripurna Raja Yoga. Children are taught his teachings and poems at school as part of regular syllabus and moral science at schools.This University was known earlier as Sri Venkateswara University PG Centre, Kadapa. This PG centre at Kadapa was established as a constituent institute of Sri Venkateswara University, Tirupati on 20 November 1977.It was upgraded as Yogi Vemana University by the Government of Andhra Pradesh through an Act of A.P. Legislative Assembly on 9 March 2006. It is located at Mittamedipalli village and Panchayat about 15 km from the Kadapa on the Kadapa-Pulivendla road. The campus is spread over 450 acres of land. Arjula Ramachandra Reddy, An Eminent Biologist, was the first vice-chancellor of Yogi Vemana University, Kadapa. The Yogi Vemana University, semi-residential in character, has unitary status and potential for phenomenal academic growth in the disciplines of Modern science and Technologies, Humanities and social science in the Years to come.C.P.Brown Library with rich collection of rare books, ancient documents and relics, situated in Kadapa is part of Yogi Vemana University providing research facilities in several disciplines.Yogi Vemana University has at present 15 departments offering courses at post graduate level in 17 disciplines in Languages/ Humanities/Physical and Bio-science, Human Resources Management, MBA & MCA and New science like Biotechnology, Bioinformatics, Geoinformatics and Earth science. The University has also introduced Five year integrated M.Sc. Courses in Earth science and Bioinformatics in the year 2007-08.Yogi Vemana University College of Engineering, Proddatur was established in 2008-2009 and renamed as YSR Engineering College of Yogi Vemana University in the year 2010. It offers six conventional disciplines of Civil, Computer Science, Electronics & Communications, Information Technology, Mechanical and Electrical & Electronics Engineering leading to the Degree of Bachelor of Engineering. Along with the above the College is offered a new course in "Metallurgical Engineering " from the ensuing academic year.Engineering campus: Wikipedia.

Gokara M.,University of Hyderabad | Sudhamalla B.,University of Hyderabad | Amooru D.G.,Yogi Vemana University | Subramanyam R.,University of Hyderabad

Background:Human serum albumin (HSA) is the most abundant protein in blood plasma, having high affinity binding sites for several endogenous and exogenous compounds. Trimethoxy flavone (TMF) is a naturally occurring flavone isolated from Andrographis viscosula and used in the treatment of dyspepsia, influenza, malaria, respiratory functions and as an astringent and antidote for poisonous stings of some insects. Methodology/Principal Findings:The main aim of the experiment was to examine the interaction between TMF and HSA at physiological conditions. Upon addition of TMF to HSA, the fluorescence emission was quenched and the binding constant of TMF with HSA was found to be KTMF = 1.0±0.01×103 M-1, which corresponds to -5.4 kcal M-1 of free energy. Micro-TOF Q mass spectrometry results showed a mass increase of from 66,513 Da (free HSA) to 66,823 Da (HAS +Drug), indicating the strong binding of TMF with HSA resulting in decrease of fluorescence. The HSA conformation was altered upon binding of TMF to HSA with decrease in α-helix and an increase in β-sheets and random coils suggesting partial unfolding of protein secondary structure. Molecular docking experiments found that TMF binds strongly with HSA at IIIA domain of hydrophobic pocket with hydrogen bond and hydrophobic interactions. Among which two hydrogen bonds are formed between O (19) of TMF to Arg 410, Tyr 411 and another one from O (7) of TMF to Asn 391, with bond distance of 2.1 Å, 3.6 Å and 2.6 Å, respectively. Conclusions/Significance: In view of the evidence presented, it is imperative to assign a greater role of HSA's as a carrier molecule for many drugs to understand the interactions of HSA with TMF will be pivotal in the design of new TMF-inspired drugs. © 2010 Gokara et al. Source

Shanmugavelu B.,Pondicherry University | Venkatramu V.,Yogi Vemana University | Ravi Kanth Kumar V.V.,Pondicherry University
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

Glasses with compositions of (100-x) (Bi2ZnOB2O 6) - x Nd2O3 (where x = 0.1, 0.3, 0.5, 1 and 2 mol%) were prepared by melt quenching method and characterized through optical absorption, emission and decay curve measurements. Optical absorption spectra have been analyzed using Judd-Ofelt theory. The emission spectra exhibit three peaks at 919, 1063 and 1337 nm corresponding to 4F3/2 to 4I9/2, 4I11/2 and 4I 13/2 transitions in the near infrared region. The emission intensity of the 4F3/2 to 4I11/2 transition increases with increase of Nd3+ concentration up to 1 mol% and then concentration quenching is observed for 2 mol% of Nd3+ concentration. The lifetimes for the 4F3/2 level are found to decrease with increase in Nd2O3 concentration in the glasses. The decay curves of the glass up to 0.3 mol% of Nd3+ exhibit single exponential nature and thereafter the curves become nonexponential nature (0.5, 1 and 2 mol%). The nonexponential curve has been fitted to the Inokuti-Hirayama model to understand the nature of energy transfer process. © 2013 Elsevier B.V. All rights reserved. Source

Vali Pasha K.,Yogi Vemana University
Asian Journal of Pharmaceutical and Clinical Research

Prolactin and Growth Hormone are anterior pituitary hormones having multiple physiological functions and number of neurotransmitters and neuropeptides are involved in their regulation. Plasma GH, prolactin and brain GABA levels were determined at 5 and 15 mins after thirdventricular injection of glutathione at doses of 15 or 30 μg in ovariectomized steroid-primed rats. Intraventricular glutathione significantly increased plasma growth hormone (GH) levels at 5 and 15 min after injection. A 15 μg dose of glutathione significantly decreased prolactin levels at 5 min after injection. A higher dose of glutathione (30 μg) however, significantly elevated plasma prolactin levels at 5 and 15 min after injection. Glutathione at a 30 μg dose caused a significant increase in hypothalamic GABA levels at 5 and 15 min after injection where as the same dose decreased GABA levels in the cerebral cortex. The release of GH and prolactin by higher dose of glutathione may be mediated through enhanced levels of GABA. These studies demonstrate a neuroendocrine role of glutathione. Source

Philomina N.S.,Yogi Vemana University
Indian Journal of Biotechnology

Plant regeneration through somatic embryogenesis has been developed in an economically important forest tree, Sapindus mukorossi Gaetin. Calli obtained by culturing young leaf explants on MS medium containing growth regulators, 2,4-D (6.7 μM) and Kn (9.0 μM), when subjected to reduced levels of 2,4-D (2.2μM)+Kn (4.6μM), produced numerous somatic embryos. Somatic embryos developed into complete plantlets on MS medium devoid of growth regulators. The regenerated plantlets were successfully established in the soil with 90% survival frequency after a few days of acclimatization. Source

Zirconium Oxide (zirconia) nanoparticles have been prepared through hydrothermal method at different calcinatation temperatures. The structural properties of zirconia powders were characterized by X-ray diffraction (XRD) technique. The sample prepared at 400 °C shown the mixed phase with co-existence of cubic and monoclinic phases and the samples prepared at 600 °C, 800 °C and 1100 °C shown the monoclinic phase. Further, surface morphology and particle size of the sample calcined at 400 °C was confirmed by transmission electron microscopy (TEM). The band gap is estimated from UV-vis spectra of zirconia particles.The frequency dependence of dielectric constant and loss were investigated at room temperature. Result showed, dielectric constant decreases with frequency. © 2016 Elsevier GmbH. Source

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