Yingkou Central Hospital

Yingkou, China

Yingkou Central Hospital

Yingkou, China
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Ding R.-H.,Huairou First Hospital | Liu B.,Beijing Jishuitan Hospital | Zhang B.,Beijing Jishuitan Hospital | Wang Y.-Q.,Beijing Jishuitan Hospital | And 2 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2013

Background: Navigation assisted minimally invasive posterior lumbar interbody fusion and pedicle screw fixation can precisely real-time guide a variety of operation under minimally invasive sleeve, and implant the pedicle screws and interbody fusion cage and other implants safely and accurately, thus can determine the decompression parts. Minimally invasive transforaminal lumbar interbody fusion is the typical approach in recent years for the successful application of minimally invasive spine surgery techniques with the advantages of small incision, less bleeding, slight tissue damage and faster recovery. Objective: To evaluate the short-term effect of minimally invasive transforaminal lumbar interbody fusion with real-time three-dimensional navigation system and open posterior transforaminal lumbar interbody fusion. Methods: Forty cases with single-level lumbar disc herniation were retrospectively analyzed. The patients were treated with minimally invasive transforaminal lumbar interbody fusion with real-time three-dimensional navigation system (20 cases) and open posterior transforaminal lumbar interbody fusion (20 cases) respectively for the comparative analysis. The fusion duration, intraoperative blood loss, postoperative drainage volume, the length of postoperative hospital stay and the length of hospital stay were compared between two groups. The wound pain and function were evaluated after treatment with visual analogue scale score and Japanese Orthopaedic Association score. Results and conclusion: All patients were followed-up for 7.7 months. The operative duration in the minimally invasive transforaminal lumbar interbody fusion group was longer than that in the open posterior transforaminal lumbar interbody fusion group, and the difference was significant (P < 0.01); the length of hospital stay and length of postoperative hospital stay of the minimally invasive transforaminal lumbar interbody fusion group were shorter than the open posterior transforaminal lumbar interbody fusion group, and the differences were significant (P < 0.01); the intraoperative blood loss of the minimally invasive transforaminal lumbar interbody fusion group was less than the open posterior transforaminal lumbar interbody fusion group, and the difference was significant (P < 0.05); the postoperative drainage volume of the minimally invasive transforaminal lumbar interbody fusion group was less than the open posterior transforaminal lumbar interbody fusion group, and the difference was significant (P < 0.01). The visual analogue scale score was significantly decreased and the Japanese Orthopaedic Association score was significantly increased in the minimally invasive transforaminal lumbar interbody fusion group at 3 days after internal fixation compared with open posterior transforaminal lumbar interbody fusion group (P < 0.01), but there were no significant differences in the visual analogue scale score and Japanese Orthopaedic Association score between the two groups before operation and 6 months after operation (P > 0.05).The results indicate that minimally invasive transforaminal lumbar interbody fusion with real-time three-dimensional navigation system is an effective method for lumbar disc herniation with the advantages of less intraoperative blood loss, less postoperative drainage volume, small trauma, short hospital stay and short-term efficacy.


Xia L.-K.,Liaoning Medical University | Wang D.,Yingkou Central Hospital | Ma J.,Liaoning Medical University | Liu H.-N.,Liaoning Medical University | Yang Y.,Liaoning Medical University
International Eye Science | Year: 2015

AIM: To observe the changes of corneal endothelial cell density and morphology after femtosecond laser small incision lenticule extraction (SMILE). METHODS: In this prospective study, 60 patients (120 eyes) with myopia or myopic astigmatism, who volunteered to receive SMILE from April 2014 to October 2014 in Shengjing Hospital of China Medical University, were divided into two groups: contact lens group (60 eyes) and non-contact lens group (60 eyes). The values of corneal endothelial cell density and the percentages of hexagonal cells, detected by NIDEK confoscan4 corneal confocal microscopy before and 1wk, 1, 6mo after surgery, were recorded and analyzed. RESULTS: All patients were with successful surgery and there were no complications intraoperative and postoperative. No differences were noted between two groups in terms of average age, refractive error, stromal ablation depth, residual stromal bed depth, and postoperative uncorrected visual acuity (P>0.05). Using the analysis of variance of repeated measurement data, there were no statistically significant differences regarding mean endothelial cell density and percentage of hexagonal cells in pre- and 1wk, 1, 6mo post-SMILE within non-contact lens group(F=0.864, 2.488; P=0.460, 0.061). In the contact lens group, no differences were found regarding mean endothelial cell density in pre- and 1wk, 1, 6mo post-operation (F=0.135, P=0.939), but there were significant differences in the percentage of hexagonal cells (F=4.913, P=0.002). The percentage of hexagonal cells decreased significantly at 1wk post-operation (30.70±4.08)% compared with preoperative (32.23±4.15)% (P=0.045), returned to the preoperative levels at 1mo after surgery (33.05±4.28)% (P=0.364), and showed no difference (P=0.091) at 6mo after surgery (34.06±5.11)% with preoperative data. The percentages of hexagonal cells in the contact lens group were significantly lower in pre- and 1wk, 1mo post-operation than those in the non-contact lens group (t=2.051, 1.723, 2.092; P=0.037, 0.042, 0.034), however, there was no statistically significant difference between two groups at 6mo after surgery (t=0.131, P=0.986). CONCLUSION: If the required residual stromal thickness limit was ≥300μm, SMILE to correct myopia or myopic astigmatism has no effect on the corneal endothelial cell density, only has short effect on the percentage of corneal hexagonal cells, which is slighter than wearing contact lens. SMILE to correct myopia is safe for corneal endothelium. Copyright 2015 by the IJO Press.


Wu H.-W.,Yingkou Central Hospital | Gao L.-D.,Yingkou Central Hospital | Wei G.-H.,Yingkou Central Hospital
Asian Pacific Journal of Cancer Prevention | Year: 2013

Objective: To study the expression of the mismatch repair proteins hMSH2 and nm23 in sporadic colorectal cancer, determine any inter-relationship, and further investigate any clinical significance. Methods: Expression of hMSH2 and nm23proteins was assessed in 87 colorectal cancer tissues by SP immunohistochemistry, with analysis of survival using follow-up data. Results: In the sporadic colorectal cancer tissues, nm23 protein expression appeared independent of the histological type (P > 0.05), but correlated with the invasion depth and lymphatic metastasis (P < 0.05). In contrast, hMSH2 protein expression was not significantly correlated with these clinicopathologic features (P > 0.05), although it positively correlated with that of nm23 protein in the sporadic colorectal cancers (rs=0.635, P < 0.05). Combined expression ofthe two was found to be related with invasion depth, lymphatic metastasis and prognosis of sporadic colorectal cancer (P< 0.05). Conclusion: nm23 protein level was related with the degree of malignancy, and could be used as an index to predict the invasion and metastasis potential. The expression of hMSH2 protein is positively correlated that of nm23 protein, and the combined expression of the two has certain guiding significance for the prognosis of sporadic colorectal cancer.

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