Yeshwant Mahavidyalaya

Nānded, India

Yeshwant Mahavidyalaya

Nānded, India

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Baig M.M.V.,Yeshwant Mahavidyalaya
Saudi Journal of Biological Sciences | Year: 2014

Cell cultures of Psoralea corylifolia L. were established from the leaf disk derived callus. The effect of different biotic elicitors prepared from the fungal extract (. Aspergillus niger and Penicillium notatum), yeast extract and chitosan with different concentrations was studied. The increased synthesis of psoralen in 16-day old cell cultures under 16. h of light and 8. h of dark period was studied. Elicitation of psoralen in A. niger elicitor treated cells was found 9-fold higher over control cells. Treating the cells with P. notatum, yeast extract and chitosan elicitors lead to four to seven-fold higher psoralen accumulation over control cells. The extract of A. niger at 1.0% v/v increased the significant accumulation of psoralen (9850. μg/g DCW) in the cultured cells. Our study clearly shows that all the elicitors had the potential to increase the accumulation of psoralen but the A. niger elicitor at 1.0% v/v induced maximum accumulation. © 2014.


Dhole J.A.,Yeshwant Mahavidyalaya | Dhole N.A.,Srtm University | Bodke S.S.,Yeshwant Mahavidyalaya
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

The screening and study of twenty leaf powder of different weeds belonging to 15 families and 18 generas for phytochemical constituents was performed using generally accepted laboratory technique for qualitative determinations. The constituents screened for were Alkaloids, Saponins, Tannins, Steroids and Flavonoids. The six weeds Argemone maxicana L., Cleome viscosa L., Commelina benghalensis L., Convolvulus arvensis L., Crotalaria retusa L. and Crotalaria spesiosa L. were found to contain Alkaloids, Saponins, Tannins, Steroids and Flavonoids. The Alternanthera sessilis (L.) R.Br, ex DC and Cyperus rotundus L. were found only tannin.


Khobragade C.N.,Swami Ramanand Teerth Marathwada University | Bodade R.G.,Swami Ramanand Teerth Marathwada University | Konda S.G.,Yeshwant Mahavidyalaya | Dawane B.S.,Yeshwant Mahavidyalaya | Manwar A.V.,Dnyanopasak College
European Journal of Medicinal Chemistry | Year: 2010

Pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidin-4-one derivatives have been prepared by cyclocondensation of ethyl 2-cyano-3,3-bis(methylthio)prop-2-enoate with 2-amino-4-(substitutedphenyl)thiazole to give 3-cyano-2-methylthio-4-oxo-4H-6-(substitutedphenyl)thiazolo[3,2-a]pyrimidin (2a-j) and further reacting with hydrazine hydrate to yield the target compounds (3a-j). The chemical structure of the compounds was confirmed by IR and 1H NMR spectral data. All the compounds of the series have been screened for their antibacterial and antifungal activity studies. The result revealed that all compounds showed significant antimicrobial activity. © 2010 Elsevier Masson SAS. All rights reserved.


Baviskar P.,North Maharashtra University | Chavan P.,University of Pune | Kalyankar N.,Yeshwant Mahavidyalaya | Sankapal B.,North Maharashtra University | Sankapal B.,Visvesvaraya National Institute of Technology
Applied Surface Science | Year: 2012

Simple and inexpensive solution chemistry is applied for decoration/formation CdS nanoparticles on multiwall carbon nanotubes (MWCNT's). Simple ion-by-ion mechanism is utilized for the deposition of CdS nanoparticles on MWCNT's. The size of the nanoparticles is controlled by tuning the preparative parameters which is most favorably based on ion-by-ion mechanism. The use of alkaline medium is completely avoided. Complete decoration of CdS nanoparticles on MWCNT's with cubic structure is observed by structural and surface morphological studies. The photoluminescence spectroscopy shows the two intense luminescence bands, i.e. blue and green, evidencing the presence of small size and agglomerated big size particles of CdS over MWCNT's (size-effect). The modification of MWCNT's with CdS presented in this study opens up new avenues in the design of optoelectronic and light-energy conversion devices. © 2012 Elsevier B.V. All rights reserved.


Tasneem S.,Yeshwant Mahavidyalaya
Nature Environment and Pollution Technology | Year: 2011

The fish population of aquatic systems plays a significant role in the economy, and India has vast potential for development of Inland fisheries. Barul earthen dam is a freshwater reservoir having catchment area of 1560 hectares has been constructed on Manar riverfordrinking, irrigation and pisciculture purposes. Literally there is no report on the fish fauna of Barul reservoir, hence to fill the gap, present work was undertaken. The reservoir was found to have a fauna of 24 fish species belonging to 11 Families and 4 different Orders.


Shinde S.L.,Yeshwant Mahavidyalaya | Wadje S.S.,Yeshwant Mahavidyalaya
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2011

The bark extract of five Terminalia species (T. alata, T. arjuna, T. bellerica, T. catappa, T. chebula) were used like aqueous, alcoholic and ethyl acetate extracts against five seed borne pathogenic fungi of cereals like Aspergillus flavus, Aspergillus niger, Alternaria brassicicola, Alternaria alternata and Helminthosporium tetramera). The antifungal activities of all these extracts were determined by paper disc method. Nearly all the extracts were found effective against these fungi. The positive results so obtained were compared with that of the reference standard fungicide (Carbendazim). It was found that most of the plant extracts showed more inhibitory effect against fungi than the control fungicide. © 2010 RJPBCS.


Patil S.D.,Yeshwant Mahavidyalaya | Khandekar N.,Yeshwant Mahavidyalaya | Kasawar G.B.,Yeshwant Mahavidyalaya | Shaikh K.A.,P.A. College
Arabian Journal of Chemistry | Year: 2013

A new simple isocratic chiral liquid chromatographic method was developed for the enantiomeric purity of Ramelteon [(S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl) ethyl]-propionamide], a melatonin agonist in bulk drugs. The chromatographic separation was achieved on Chiralpak AD-H, 250mm×4.6mm, 5μm column using a mobile phase system consisting of n-hexane, ethanol and methanesulfonic acid in the ratio of 900:100:0.1 (v/v/v). The mobile phase was pumped on the column at the flow rate of 1mLmin-1. Addition of methane sulfonic acid in the mobile phase enhanced chromatographic efficiency and resolution between the enantiomers. The resolution between the enantiomers was found to be more than four. The developed method was subsequently validated and proved to be accurate and precise. The experimentally established limit of detection and quantification of (R)-enantiomer were found to be 25.5 and 77.2ngml-1, respectively, for 20μl injection volumes. The percentage recovery of (R)-enantiomer was ranged from 98.5 to 101.9 in bulk drug samples of Ramelteon. The stability of Ramelteon sample in analytical solution was checked for about 48h at room temperature and was found to be stable for about 48h. The proposed method was found to be suitable and accurate for the quantitative determination of (R)-enantiomer in drug substance. © 2010.


Godavari is life line for people living on the bank of the river. Godavari river is termed as southern Ganges, which is the main source of drinking water for the people living on the bank of the river. The present investigation was undertaken to determine the pollution strength of industrial effluents in terms of temperature and dissolved oxygen, that will be required for aquatic biota to maintain aerobic condition. The water samples were collected over a period of two year monthly from February 2000 to January 2002. In the present study values of temperature were maximum in May is 38 °C and minimum in December is 23 °C and values of Dissolved Oxygen, were maximum 7.8 mg/L in winter and minimum 8.0 mg/L in summer. The values show that temperature and D.O. content are inversely proportional to each other. Copyright © EM International.


Patil A.T.,P.A. College | Patil S.D.,Yeshwant Mahavidyalaya | Shaikh K.A.,P.A. College
Journal of Liquid Chromatography and Related Technologies | Year: 2011

A sensitive stability indicating reverse phase high performance liquid chromatographic method was developed for the simultaneous determination of formoterol fumarate and ciclesonide in dry powder inhaler. The chromatographic separation was achieved on Hypersil BDS C 8 250×4.6mm, 5um column using a mobile phase consisting of 0.1% orthophospheric acid and acetonitrile in the ratio of 35:65 (v/v), at a flow rate of 2.0mLmin -1. The column compartment temperature was set at 40°C. The typical HPLC chromatograms were extracted at 214nm using photodiode array detector (PDA). The described method shows excellent linearity over a range of 3.6μgmL -1 to 1.1ngmL -1 for formoterol fumarate and 120μgmL -1 to 34ngmL -1 for ciclesonide. The correlation coefficient for formoterol fumarate and ciclesonide was 0.9998. The limit of detection and limit of quantification for formoterol fumarate was 0.33ngmL -1, 1.1ngmL -1 and for ciclesonide 10.2ngmL -1, 34ngmL -1, respectively. The proposed method was found to be very sensitive and accurate for the determination of Formoterol Fumarate and ciclesonide indry powder inhaler. Copyright © Taylor & Francis Group, LLC.


Nanware S.S.,Yeshwant Mahavidyalaya
Biochemical and Cellular Archives | Year: 2015

This work was carried out to study the histopathological alterations in the intestine of Capra hircus, naturally infected with the Anoplocephalidean cestode, Moniezia maharashtrae Nanware, (2010). The cestode Moniezia maharashtrae approaches the villi floating in the lumen and some worms get attached to the tissues of intestine. The villi of crypts of liberkuhn were ruptured, destructed and shifted apart by penetration of worm. Cellular infiltration occurred at the point of attachment by release of pharmacologically active agent histamine from mast cells. These dilations showed increased blood supply to the affected area. Vessel walls became thick and polymorphonuclear leucocytes adhered to host tissue. Few worm successfully entered the intestine forming ulceration in intestinal wall. The parasite derives nutritive material, required for growth from the host tissue by causing damage to it.

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