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Lee D.G.,Chung - Ang University | Cho S.,Chung - Ang University | Lee J.,Chung - Ang University | Yang S.,Chung - Ang University | And 4 more authors.
Natural Product Sciences | Year: 2015

Content analysis of flavonoids (epicatechin, epicatechin gallate, and rutin) present in the leaves of Boehmeria nivea (originating from Geumsan-myeon, Biin-myeon, Hansan-myeon, and Baeksu-eup) and their commercial products (ramie tteok, ramie songpyeon, ramie bory-tteok, and ramie tea) was conducted by HPLC. The content of epicatechin, epicatechin gallate, and rutin was highest in the leaves of B. nivea from Geumsanmyeon (0.138 mg/g), Baeksu-eup (1.654 mg/g) and Geumsan-myeon (12.205 mg/g), respectively. With respect to commercial products, the content of epicatechin and epicatechin gallate was highest in ramie tea, with concentrations of 1.879 and 1.090 mg/g, respectively. Given these flavonoid concentrations, B. nivea leaf extracts have the potential to be used as additives in natural medicinal products, health supplements, and beverages. © 2015, Korean Society of Pharmacognosy. All rights reserved. Source


Lee D.G.,Chung - Ang University | Lee A.Y.,Pusan National University | Kim S.-J.,Chungnam National University | Jung Y.-S.,Yeong Gwang Agricultural Technology Center | And 3 more authors.
Natural Product Sciences | Year: 2014

This research aimed to investigate the antibacterial activity of Lycoris radiata. The methanol extract and solvent fractions from L. radiata exhibited antibacterial activities against Escherichia coli, Staphylococcus aureus, and Helicobactor pylori. Open-column chromatography was used to isolate phytochemical constituents from L. radiata; spectroscopic analysis elucidated their structures as β-sitosterol (1), daucosterol (2), Omethyllycorenine (3), lycorenine (4), lycoricidinol (5), lycorine (6), and lycoricidine (7). Further testing of compounds 1 - 7 revealed antibacterial effects against E. coli, S. aureus, and H. pylori, which suggested the potential of these substances as antibacterial agents. We determined that compounds 1 and 2, isolated from the nhexane fraction, were more effective against S. aureus and H. pylori. Compound 4, isolated from the methylene chloride fraction, exhibited noticeable antibacterial effects against E. coli. This study is the first report on the antibacterial activities of phytochemical constituents from L. radiata against E. coli, S. aureus, and H. pylori. © 2014, Korean Society of Pharmacognosy. All rights reserved. Source


Lee A.Y.,Pusan National University | Wang X.,Pusan National University | Lee D.G.,Chung - Ang University | Kim Y.-M.,Yeong Gwang Agricultural Technology Center | And 5 more authors.
Journal of Applied Biological Chemistry | Year: 2014

The purpose of this study was to evaluate the biological activities of extracts of ramie (Boehmeria nivea (L.) Gaud.), hereafter referred to as Bn. Bn extracts from various collecting area were extracted with methanol. Two extracts from our study, Bn-13 and -82, showed significant antioxidant properties, likely due to their ability to scavenge free radicals. In addition, Bn extracts showed stronger anti-bacterial activity against Escherichia coli (Bn-40), Stapylococcus aureus (Bn-33), and Helicobacter pylori (Bn-05). In addition, this study was conducted to evaluate the anti-inflammatory effects of Bn extracts in lipopolyssacharide (LPS)- and interferon-γ (IFN-γ)-stimulated RAW 264.7 macrophages cells. Bn-37 significantly inhibited the production LPS/IFN-γinduced nitric oxide. The most noteworthy anti-cancer effect was found in Bn-23. Bn-08 showed inhibition of aldose reductase. This study provides basic information for the development of functional foods. © The Korean Society for Applied Biological Chemistry 2014. Source

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