Time filter

Source Type

Okuyan H.,Sakarya Education and Research Hospital | Altin C.,Yenimahalle State Hospital
Indian Journal of Pharmacology | Year: 2013

Itraconazole is a broad-spectrum antifungal agent. It rarely leads to adverse the cardiovascular effects, especially heart failure. We present here a case of a 60-year-old female patient with itraconazole induced heart failure.

Kapisiz N.S.,Ankara Education and Training Hospital | Kapisiz H.,Yenimahalle State Hospital
Journal Phlebology and Lymphology | Year: 2014

Asymmetric left face edema due to left subclavian vein thrombosis and its management is presented in this case report. 30 years-old woman with left arm and face edema had thrombosis from the middle part of left subcavian untill superor vena cava and brachiocephalic vein. Low molecular weight heparin and oral anticoagulant therapy were shown to provide clinical improvement, although it did not provide improvement in the anatomy. The literature is reviewed.

Yilmaz H.,Ankara University | Cakmak M.,Ankara University | Inan O.,Yenimahalle State Hospital | Darcin T.,Agrl State Hospital | Akcay A.,Ankara University
Journal of Endocrinological Investigation | Year: 2015

Purpose: Galectin-3 (Gal-3) is a marker of cardiac fibrosis and predicts incident heart failure. Gal-3-deficient mice are resistant to multiple low-dose streptozotocin-induced diabetes. Recent experimental studies suggested an important role for Gal-3 in the regulation of adiposity, metaflammation and type 2 diabetes. This study aimed to examine the relationship between Gal-3 and newly diagnosed prediabetes and diabetes. Methods: Gal-3 concentrations were measured in 118 participants and 56 age- and sex-matched healthy controls. All subjects underwent a 75-g oral glucose tolerance test and were stratified into normal, prediabetic, and diabetes mellitus subgroups. DM was defined as a plasma glucose level ≥126 mg/dL in the fasting state or ≥200 mg/dL in the second hour after glucose loading. Impaired fasting glucose was defined as an FPG level of 100-125 mg/dL, and impaired glucose tolerance was defined as a 2-h plasma glucose level of 140-199 mg/dL. Results: Sixty-one patients had prediabetes (Group 1), 57 had diabetes (Group 2), and 56 had neither diabetes nor prediabetes (Group 3). Gal-3 levels correlated with FPG (r = 0.787, P < 0.01), 2hPG (r = 0.833, P < 0.01), CRP (r = 0.501, P < 0.01), and HOMA-IR (r = 0.518, P < 0.01). Gal-3 levels were higher in Group 2 than in Groups 1 and 3 [1,053.9 (358.1) and 744.1 (119.3) vs. 481.7 (175.4) pg/mL; P < 0.001]. Gal-3 is an independent predictor of diabetes in multivariate logistic analysis. In ROC analysis, a Gal-3 cutoff value of 803.55 pg/mL diagnoses diabetes with a sensitivity of 80.7 % and a specificity of 85.5 % (AUC = 0.912). Conclusions: Gal-3 is a promising biomarker for detecting prediabetes and diabetes. © 2014 Italian Society of Endocrinology (SIE).

Kapisiz N.S.,Ankara Education and Training Hospital | Kapisiz H.,Yenimahalle State Hospital
Journal Phlebology and Lymphology | Year: 2014

The management of acute renal failure and hemorrhage in a patient after embolectomy is presented in this article. A 47 years-old female patient was operated for acute arterial occlusion of lower extremity. She developed oligo-anuric renal failure and needed hemodialysis in postoperative first day. Progressive huge hematoma developed at the site of jugular catheter and bleeding started at all vascular access sites a few hours after hemodialysis. Besides early diagnosis and surgical intervention, meticulous follow up of cardiac, renal and lung functions play very important role in treatment of acute arterial occlusions.

Yaman O.,Tepecik Education and Training Hospital | Demir T.,TOBB University of Economics and Technology | Arslan A.K.,Yenimahalle State Hospital | Iyidiker M.A.,TOBB University of Economics and Technology | And 3 more authors.
Turkish Neurosurgery | Year: 2015

Aim: One of the most common problems with transpedicular screws is screw pullout. This study was conducted to measure the pullout strengths of newly designed transpedicular screws. Material and Methods: The design of the three group screws were conical cored standard pedicle screw (Type A), dual threaded pedicle screw (Type B), dual core and dual threaded pedicle screw (Type C), respectively. Polyurethane (PU) blocks in 25 mm and 50 mm thickness were used to investigate the effect of just the pedicle on pullout strength and both distal (vertebral body) and proximal (pedicle) parts of the screw. The screws were also tested in ovine lumbar vertebrae. Results: Type C screw exhibited 5.9% and 12.9% higher pullout strength than Type A and Type B, and 15.4% and 8.6% higher pullout strength than Type A and Type B, respectively on 25 mm and 50 mm thick PU foam block. Type C also exhibited 74.5% and 22.5% higher pullout strength than Type A and Type B, respectively on the ovine vertebrae. Conclusion: Transpedicular screws redesigned with modified helical angles exhibit higher pullout strength compared to the classical transpedicular screws and can be inserted more rapidly with the same number of screwing rounds result with doubled insertion depth.

Discover hidden collaborations