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Kagawa, Japan

Matsuoka M.,Yashima General Hospital | Kitamura Y.,Tokushima University | Abe K.,Tokushima University | Takeda N.,Tokushima University | Endo A.,Shikoku Central Hospital
Practica Oto-Rhino-Laryngologica | Year: 2015

We report herein on a 75-year-old woman with sinonasal-type hemangiopericytoma (HPC). She complained of nasal bleeding and a nasal tumor originated from the left nasal septum was found. It was successfully resected using endoscopic sinus surgery without preoperative embolization, because we were uncertain of its feeding artery. Its pathological examination gave a diagnosis of sinonasal-type of HPC. The sinonasal-type HPC is a rare benign sinonasal tumor, but WHO has classified it as a borderline malignancy, because it may have multiple relapses. Our patient remained free of relapse 36 months after the treatment. Source


Kitamura Y.,Tokushima University | Mizuguchi H.,Tokushima University | Ogishi H.,Tokushima University | Kuroda W.,Yashima General Hospital | And 3 more authors.
Acta Oto-Laryngologica | Year: 2012

Conclusions: These findings suggest that the down-regulation of interleukin (IL)-5 gene expression in collaboration with the suppression of histamine H1 receptor (H1R) gene expression in the nasal mucosa provides the basis for better therapeutic effects of preseasonal prophylactic treatment with antihistamines in patients with seasonal allergic rhinitis caused by Japanese cedar pollen. Objectives: The effects of prophylactic administration of antihistamines on the expression of IL-5 and IL-33 mRNA in the nasal mucosa of the patients with pollinosis were investigated. Methods: Eight patients had already visited the hospital before the peak pollen period and started preseasonal prophylactic treatment with antihistamines. Seventeen patients who first visited the hospital during the peak pollen period were designated as the no treatment group. After local anesthesia, nasal mucosa was obtained by scraping the inferior concha with a small spatula during the peak pollen period. Results: During the peak pollen period, the expression of IL-5 mRNA, but not that of IL-33 mRNA, in the nasal mucosa of patients receiving preseasonal prophylactic treatment with antihistamines was significantly lower in comparison with that of patients without treatment. Moreover, there was a significant correlation between the expression of IL-5 mRNA and the nasal symptoms or the expression of H1R mRNA. © Informa Healthcare. Source


Sekine K.,Tokushima University | Imai T.,Osaka University | Tachibana F.,Tachibana ENT Clinic | Matuda K.,Tokushima University | And 2 more authors.
Equilibrium Research | Year: 2010

We report a case of Costen's syndrome that showed chewing-induced nystagmus and vertigo. A 31-year-old woman visited our hospital complaining of chewing-induced vertigo 5 days after dental therapy. During chewing a stick of gum, she complained of vertigo and showed nystagmus beating to the right, the direction of which changed to the left thereafter. No spontaneous and positional nystagmus or any abnormalities in the neurological examination could, however, be found. The chewing-induced nystagmus and vertigo gradually disappeared within 2 weeks. Costen's syndrome is associated with various symptoms due to temporomandibular dysfunction. In the case, it is suggested that malinterdigitation after dental therapy caused temporomandibular dysfunction, resulting in the chewing-induced nystagmus, therefore, Costen's syndrome was diagnosed. Eustachian tube hypothesis, Tensor tympani hypothesis and otomandibular ligament hypothesis that accounted for temporomandibular dysfunction-induced aural symptoms in patient with Costen's syndrome had been proposed, but recently were withdrew. On the other hand, it is reported that reciprocal connections between trigeminal and vestibular nuclei. The trigeminal somatosensory input associated with temporomandibular dysfunction after dental therapy may cause chewing-induced nystagmus via the trigemino-vestibular connection in the brainstem in the case. Source


Sato G.,Yashima General Hospital | Sekine K.,Tokushima University | Matsuda K.,Tokushima University | Takeda N.,Tokushima University
Acta Oto-Laryngologica | Year: 2012

Conclusion: The findings suggest that it is easy for otoconial debris dislodged from the utricle to fall into the posterior semicircular canal (PSCC) or the horizontal semicircular canal (HSCC) of the undermost ear during sleep, but not to exit from the uppermost ear in patients with benign paroxysmal positional vertigo (BPPV). Objective: The aims of the present study were two-fold. (1) To examine the association between the preferred side of head-lying during sleep and the side of the affected ear in patients with both posterior canal BPPV (P-BPPV) and horizontal canal BPPV (H-BPPV). (2) To see whether that position affects the time course in remission of their positional vertigo. Methods: One hundred and sixteen patients with P-BPPV and 40 patients with H-BPPV who showed a habitual preference for right or left side sleeping position were included in this study. Results: The side of the affected ear was significantly associated with the head-lying side during sleep in patients with P-BPPV and was closely but not significantly associated with it in patients with H-BPPV. However, the head-lying side during sleep did not affect the remission rate of their positional vertigo. © 2012 Informa Healthcare. Source


Mori N.,Kagawa University | Yanagihara T.,Kagawa University | Nagasaka H.,Yashima General Hospital | Katsuki N.,Kagawa University | And 5 more authors.
Journal of Obstetrics and Gynaecology Research | Year: 2011

A capillary hemangioma with hydrocephalus in the posterior fossa of a fetus was detected on ultrasonography at 38 weeks and 4 days of gestation. A well-defined, round tumor with a mixed pattern occupied the posterior fossa, and the normal cerebellum was significantly compressed by this tumor. No other anomaly was detected. Delivery was induced because of rapidly progressive hydrocephalus, and an otherwise healthy female infant weighing 2800 g was delivered vaginally at 39 weeks and 4 days of gestation. Histologic examination of the lesion through biopsy demonstrated capillary hemangioma. The tumor spontaneously decreased in size, and disappeared six months later. The child is now 2 years of age, and is developing normally. © 2010 Japan Society of Obstetrics and Gynecology. Source

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