Itoh G.,Yamamoto Daisan Hospital |
Ogawa M.,Yamamoto Daisan Hospital |
Osaka H.,Yamamoto Daisan Hospital |
Matsuzaki T.,Yamamoto Daisan Hospital |
And 2 more authors.
Japanese Journal of Cancer and Chemotherapy | Year: 2012
A 68-year-old man was admitted to our hospital because of an abdominal tumor. Computed tomography (CT) showed a 6 cm tumor in the abdominal cavity. Surgery was performed. Upon laparotomy, a 6 cm tumor was found at the small intestine (210 cm) on the anal side from the Treitz ligament. A partial resection of the small intestine was performed. Immunohistochemistry showed positive staining for c-kit, and the diagnosis of gastrointestinal stromal tumor was confirmed. Multiple liver metastases and a lung metastasis were observed over the next 2 years. We started chemotherapy with imatinib mesylate at a dose of 400 mg/day. The size of the tumors was unchanged, and no new lesion was observed. The patient has been alive and well as of 6 years after the initial operation.