Yamaguchi, Japan
Yamaguchi, Japan

Yamaguchi University is a national university in Yamaguchi Prefecture, Japan. It has campuses at the cities of Yamaguchi and Ube. Wikipedia.

SEARCH FILTERS
Time filter
Source Type

Patent
Daicel Corporation and Yamaguchi University | Date: 2015-07-07

Provided is a compound that thickens and/or gelatinizes a fluid organic substance to a desired viscosity, or uniformly stabilizes a composition containing the fluid organic substance. Also provided are: a thickening/stabilizing agent including the compound, a thickened/stabilized composition including the thickening/stabilizing agent and a fluid organic substance, and a method for producing the composition. The compound according to the present invention is represented by Formula (1): (R^(2)HNOC)_(4-n)R^(1)(CONHR^(3))_(n)(1) where R^(1 )is a group resulting from removing four hydrogen atoms from the structural formula of an aromatic hydrocarbon or cyclohexane; R^(2 )is, independently in each occurrence, an aliphatic hydrocarbon group containing 1 to 4 carbon atoms; R^(3 )is, independently in each occurrence, an aliphatic hydrocarbon group containing 6 or more carbon atoms; and n is an integer of 1 to 3.


Patent
Daicel Corporation and Yamaguchi University | Date: 2017-05-17

Provided is a compound that thickens and/or gelatinizes a fluid organic substance to a desired viscosity, or uniformly stabilizes a composition containing the fluid organic substance. Also provided are: a thickening/stabilizing agent including the compound, a thickened/stabilized composition including the thickening/stabilizing agent and a fluid organic substance, and a method for producing the composition. The compound according to the present invention is represented by Formula (1):(R^(2)-HNOC)_(4-n)-R^(1)-(CONH-R^(3))_(n)(1)where R^(1) is a group resulting from removing four hydrogen atoms from the structural formula of an aromatic hydrocarbon or cyclohexane; R^(2) is, independently in each occurrence, an aliphatic hydrocarbon group containing 1 to 4 carbon atoms; R^(3) is, independently in each occurrence, an aliphatic hydrocarbon group containing 6 or more carbon atoms; and n is an integer of 1 to 3.


The present invention relates to a method for evaluating the activity level of mesenchymal stem cells, and a method for culturing mesenchymal stem cells using the evaluation method in the field of culturing mesenchymal stem cells for regenerative medicine, and further, a method for producing a therapeutic agent for liver dysfunction and a therapeutic agent for liver dysfunction. This method for evaluating mesenchymal stem cell activity according to the present invention comprises an assay step for assaying the amount of adenylate kinase 4 (AK4) in the mesenchymal stem cells; and a determination step for determining the activity level of the mesenchymal stem cells from the assayed amount of adenylate kinase 4. In this method, the activity level of mesenchymal stem cells can be evaluated from the assayed amount of AK4, for instance, if the mitochondrial activity level of mesenchymal stem cells is high, the mesenchymal stem cells can be evaluated as ideal for use as a therapeutic agent, while if mitochondrial activity of the mesenchymal stem cells is low and aging does not proceed, the mesenchymal stem cells can be evaluated as suitable for subculture.


Patent
Daicel Corporation and Yamaguchi University | Date: 2017-03-22

The present invention provides a compound that thickens or gels a fluid organic substance to a desired viscosity or homogeneously stabilizes a composition containing a fluid organic substance, a thickening/stabilizing agent containing the compound, a thickened/stabilized composition containing the thickening/stabilizing agent and a fluid organic substance, and a method for producing a thickened/stabilized composition. The compound of the present invention is represented by the following formula (1). In the formula, R^(1) and R^(2) are different from each other and represent an aliphatic hydrocarbon group having not less than 4 carbon atoms, and n represents an integer of 1 to 3. The thickening/stabilizing agent of the present invention contains the compound.


Patent
Yamaguchi University | Date: 2015-04-22

An object is to provide a thermotolerant yeast capable of assimilating xylose to produce ethanol or a mutant strain thereof and a method for producing ethanol by assimilation of xylose. There is used a yeast, Kluyveromyces marxianus strain No. 21 (accession number: NITE BP-01739), or a mutant strain thereof that has xylose assimilation ability and ethanol production ability when cultured at 30 C. under aerobic conditions using a culture medium containing xylose as a sugar source. Also performed is a method for producing ethanol, comprising culturing the yeast or the mutant strain thereof under aerobic conditions using a culture medium containing xylose as a sugar source.


Patent
Yamaguchi University | Date: 2016-10-14

The present invention addresses the problem of providing a novel therapeutic agent for keratoconjunctive disorders. As a means for solving the problem, a therapeutic agent for keratoconjunctive disorders which contains a RAR agonist as an active ingredient is provided. The therapeutic agent exhibits an excellent ameliorating effect in a keratoconjunctive disorder model, and is therefore useful as a therapeutic agent for keratoconjunctive disorders such as corneal ulcer, corneal epithelial abrasion, keratitis, dry eye, conjunctivitis, chronic superficial keratitis, corneal erosion, persistent corneal disorders, superficial punctate keratopathy, corneal epithelial defects, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, infectious keratitis, noninfectious keratitis, infectious conjunctivitis and noninfectious conjunctivitis. The therapeutic agent is also useful as a therapeutic agent for corneal scarring and conjunctival scarring both associated with keratoconjunctive disorders.


Patent
Yamaguchi University | Date: 2017-08-16

An object of the present invention is to provide CAR-expressing T cells that coexpress a chimeric antigen receptor (CAR) and a T cell immune function-enhancing factor and have a high immunity-inducing effect and antitumor activity, and to provide a CAR expression vector for the preparation of the CAR-expressing T cells. A CAR expression vector comprises a nucleic acid encoding a chimeric antigen receptor (CAR) and a nucleic acid encoding a T cell immune function-enhancing factor, wherein the nucleic acid encoding an immune function-enhancing factor is a nucleic acid encoding interleukin-7 and a nucleic acid encoding CCL19, a nucleic acid encoding a dominant negative mutant of SHP-1, or a nucleic acid encoding a dominant negative mutant of SHP-2, or a CAR-expressing T cell introduced with the CAR expression vector are prepared.


Patent
Yamaguchi University | Date: 2015-07-01

A plurality of branch bars is provided on opposing sides of paired strut pieces connected by links in a strut to protrude from one towards the other side, and a plurality of ratchet teeth is formed on the side of the branch bars respectively. When a stent made of polymer material having a cylindrical constitution in which a plurality of struts is connected by links is deformed to enlarge its diameter, the paired struts are deformed to come near to each other, so that the branch bars overlap each other with the ratchet teeth formed thereon engaging with each other. As the effect of engagement of the ratchet teeth with each other, while deformation of the struts so as to enlarge the diameter of the stent is allowed, deformation so as to reduce the diameter of the stent is inhibited.


Patent
Daicel Corporation and Yamaguchi University | Date: 2015-05-01

The present invention provides a compound that thickens or gels a fluid organic substance to a desired viscosity or homogeneously stabilizes a composition containing a fluid organic substance, a thickening/stabilizing agent containing the compound, a thickened/stabilized composition containing the thickening/stabilizing agent and a fluid organic substance, and a method for producing a thickened/stabilized composition. The compound of the present invention is represented by the following formula (1). In the formula, R^(1 )and R^(2 )are different from each other and represent an aliphatic hydrocarbon group having not less than 4 carbon atoms, and n represents an integer of 1 to 3. The thickening/stabilizing agent of the present invention contains the compound.


Patent
Daicel Corporation and Yamaguchi University | Date: 2017-09-27

Provided are: a compound, a thickening/stabilizing agent including the compound, a thickened/stabilized composition including the thickening/stabilizing agent and a fluid organic substance, and a method for producing the thickened/stabilized composition, where the compound effectively thickens the fluid organic substance to a desired viscosity and effectively uniformly stabilizes the formulation of the composition containing the fluid organic substance via thickening of the fluid organic substance. The thickening/stabilizing agent according to the present invention includes a compound represented by Formula (1):(R^(2)-HNOC)_(4-n)-R^(1)-(CONH-R^(3))_(n)(1)where R^(1) is a group resulting from removing four hydrogen atoms from the structural formula of butane; R^(2) and R^(3) are different from each other and are aliphatic hydrocarbon groups each containing 4 or more carbon atoms; and n is an integer of 1 to 3.

Loading Yamaguchi University collaborators
Loading Yamaguchi University collaborators