Yagishitagiken Co.

Wako, Japan

Yagishitagiken Co.

Wako, Japan
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Fukuyama R.,Tokyo University of Science | Taniguchi J.,Tokyo University of Science | Yoshikawa K.,Yagishitagiken Co. | Yagishita H.,Yagishitagiken Co.
Microelectronic Engineering | Year: 2016

We developed a process for micropiercing a titanium (Ti) sheet to produce a barrier membrane for guided tissue regeneration that uses a roll-to-substrate (RTS) method. We performed an experiment using pure Ti sheets with thicknesses of 5, 10, 15, and 20 μm. With the RTS process, the lining film for the perforator of the Ti sheet is very important in ensuring success. We evaluated the optimum thickness of the lining film and the roll speed for the Ti sheet piercing process. At a roll speed of 1 m/min, the experimental values of Pmax agreed reasonably well with the calculated values. The aperture ratio was more than 90% for all Ti sheet thicknesses. For a stage speed of 3 m/min and load of 1000 N, the aperture ratio was more than 90% for only the 5- and 10-μm-thick Ti sheets. A load of 1000 N or more was necessary to perforate the 15- and 20-μm-thick Ti sheets. In terms of productivity, approximately 454,000 through-holes per second were formed on 5- and 10-μm-thick Ti sheets with a roll speed of 3 m/min. © 2015 Published by Elsevier B.V.


Fukuyama R.,Tokyo University of Science | Taniguchi J.,Tokyo University of Science | Yoshikawa K.,Yagishitagiken Co. | Yagishita H.,Yagishitagiken Co.
Microelectronic Engineering | Year: 2015

Titanium (Ti) has many valuable properties, such as its light weight, high strength, and corrosion resistance. Consequently, it has attracted attention as a highly biocompatible material for implants in the human body. A process has been developed for micropiercing Ti by a roll-to-substrate method to produce a barrier membrane for guided tissue regeneration. In this method, a concavo-convex shaped mold is positioned between a press roll and a stage that moves the substrate while the roll presses it. The technique has low costs, operates at room temperature, and permits high-throughput continuous piercing without damage from thermal effects or oxidation. The processed membrane is suitable for use in biocompatible devices. We investigated the characteristics of a Ti sheet perforated in the presence or absence of a lining film and their dependence on the pressing load. In the absence of a lining film, the aperture ratio was poor and, moreover, the pattern of the mold did not penetrate the film evenly. In contrast, when a lining film was used, almost complete penetration was achieved. The size of the holes that penetrated the film increased with increasing load. © 2015 Elsevier B.V.All rights reserved.

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