Ding C.,Xinjiang University |
Ding C.,Xinjiang Product Quality Supervision and Inspection Research Institute |
Xu S.,Xinjiang University |
Lin J.,Xinjiang University |
And 6 more authors.
Journal of Polymer Research | Year: 2012
The layer-by-layer (LbL) assembled multilayer films are widely used in controlled drug delivery. Here, hydrogen-bonded LbL multilayer films were assembled through alternating deposition of poly(vinylpyrrolidone) (PVPON) and poly(acrylic acid) (PAA) on glass slides. Methylene blue (MB) was used as a model drug to investigate the loading and release ability of the prepared multilayer film. The results showed that the loading rate of MB was greatly influenced by pH value of the dye solution, and the release rate was controlled both by ionic strength and pH value of immersing solution. The result also indicated that the loading and release of MB were reversible and can be repeated many times. It suggested that the PVPON/PAA multilayer film had potential applications in drug delivery and controlled release. © 2012 Springer Science+Business Media B.V.
Li S.,Xinjiang University |
Yin C.,Xinjiang Product Quality Supervision and Inspection Research Institute |
Ren S.,Xinjiang Product Quality Supervision and Inspection Research Institute |
Yang T.,Xinjiang Product Quality Supervision and Inspection Research Institute |
And 2 more authors.
Journal of Separation Science | Year: 2015
A simple strategy was developed for the preparation of multi-hollow magnetic molecularly imprinted polymers by incorporating 3-indolebutyric acid and ferroferric oxide nanoparticles simultaneously into a poly(styrene-co-methacrylic acid) copolymer matrix. The as prepared absorbents were characterized using scanning electron microscopy, Fourier-transform infrared spectroscopy and mercury porosimetry. The adsorption isotherms of indolebutyric acid revealed that there are two types of affinity binding sites in the absorbents. The apparent maximum binding capacity and dissociation constant were 17.88 mg/g and 158.7 μg/mL for high-affinity binding sites and 9.310 mg/g and 35.04 μg/mL for low-affinity binding sites, respectively. The results testified that multi-hollow magnetic molecularly imprinted polymers possessed excellent recognition capacity and fast kinetic binding behavior to the objective molecules due to the high specific surface area as large as 511.3 m2/g. Recoveries of 75.5-86.8% were obtained for the indolebutyric acid spiked at three concentration levels in blank and pear samples. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PubMed | Xinjiang Product Quality Supervision and Inspection Research Institute and Xinjiang University
Type: Journal Article | Journal: Journal of separation science | Year: 2016
In this work, a novel dual-template magnetic molecularly imprinted polymer particle for dicofol and chlorpyrifos-methyl was prepared through oil-in-water emulsifier-free emulsion technology. The resulting magnetic particles were characterized with electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction. It was found that as-prepared particles were well-shaped spheres with multi-hollow structures and of a size around 125 m. Meanwhile it showed a good magnetic sensitivity. The results testified that multi-hollow magnetic molecularly imprinted polymers possessed excellent recognition capacity and fast kinetic binding behavior to the objective molecules. The maximum binding amounts toward dicofol and chlorpyrifos-methyl were 31.46 and 25.23 mg/g, respectively. The feasibility of the use of the particles as a solid-phase extraction sorbent was evaluated. Satisfactory recoveries ranging from 90.62 to 111.47 and 91.07 to 94.03% were obtained for dicofol and chlorpyrifos-methyl, respectively, spiked at three concentration levels from real samples. The Langmuir isotherm equation provided an excellent fit to the equilibrium sorption data of either dicofol or chlorpyrifos-methyl. It provided a novel way to advise dual-template magnetic molecularly imprinted polymer particles to adsorb pesticides with high selectivity.