Xu X.-H.,Haian County Peoples Hospital |
Dinc Y.-Q.,Fudan University |
Ma F.-P.,Xianyang City Central Hospital
Journal of Practical Oncology | Year: 2013
Objective To examine the MRI features and the pathological basis of hepatic focal nodular hyperplasia (FNH) in diagnosed and misdiagnosed cases. Methods The MRI image data of 62 pathologically confirmed hepatic FNH lesions in 49 patients were retrospectively analyzed. The characteristics of MRI findings from 12 hepatic FNH cases of misdiagnosis or uncertain diagnosis were also analyzed. Results Hepatic FNH lesions were mostly distributed in the subcapsular area of the liver or prominent beyond the liver contours (57/62). The lesions larger than 3 cm presented lobular or shallow lobular shapes (48/50). The majority of hepatic FNH lesions were non-encapsulated (57/62) and some lesions had pseudo-capsule-like enhancement (5/62). The scar sign and enhancement pattern were different according to lesion size, the lesions larger than 3 cm had relatively higher presence rate of scar sign (43/50). Central scar enhancement was higher in lesions sized 3-7 cm (15/39) and scar contraction in lesions >7 cm (8/11) was relatively higher. The reasons of misdiagnosis and uncertain diagnosis in most of cases might he found after carefully reading MRI images. Conclusion The diagnostic accuracy of hepatic FNH can be improved if we are aware of the difference of the presence and enhancement pattern of central scar in different tumor size. Pay attention to image details combined with clinical data can improve differential diagnosis between atypical hepatic FNH and other lesions.