Time filter

Source Type

Xianning, China

Ding J.-G.,Xianning College
Journal of Clinical Rehabilitative Tissue Engineering Research | Year: 2010

BACKGROUND: Mesencephalon-derived neural stem cells (NSCs) differentiate into dopaminergic neurons in hypoxia and transgenic condition with body culture morphology and function of adequate maturity of dopamine neurons. Mesencephalon-derived NSCs become ideal seed cells for the treatment of Parkinson's disease with the rapid development of stem cell transplantation in the past few years. OBJECTIVE: To review research progress of mesencephalon-derived NSCs ransgene for treating Parkinson's disease. METHODS: PubMed database was retrieved in computer (1992-01/2006-12), with the key words of "Neural Stem Cell(NSC), Mesencephalic Neural Stem Cell (M-NSC), Neural Stem ell Transplant, Parkinson's Disease (PD)". Simultaneously, China Journal Full-Text Database (2003-01/2008-12) was retrieved with the same key words. RESULTS AND CONCLUSION: The NSCs and in the basic research of M-NSCs and M-NSCs transplantation in the treatment of PD-related documents were selected. A total of 83 documents were collected. Following reading titles and abstracts, 14 studies with irrelative objectives and contents, 16 studies with repetitive contents and 53 articles of Meta analysis were excluded. Totally 47 literatures were included. The main pathologic changes of Parkinson's disease are a dopaminergic neuron degeneration of necrosis in the brain substantia nigra. Using genetically modified neural stem cells in treatment of Parkinson's disease is the most recognized as the most promising treatment. In the hypoxia conditions, transgenic culture of brain-derived neural stem cells can be ffectively induced to differentiate into dopaminergic neurons, provide xperimental basis for in vitro sufficient amount of dopamine neuron transplantation in the treatment of PD. Basic research of neural stem cells have achieved certain results, but clinical and experimental study of neural stem cell transplantation in the treatment of PD is still stuck in the laboratory stage. Mesencephalic neural stem cell biological haracteristics, isolation, proliferation and differentiation are subject to further study. In addition, biological safety problems using mesencephalic neural stem cells in the human body gradually attracted the attention of the people. In vitro neural stem cells of many assages would occur, and will bring certain side effects, and tumorigenicity remains in further exploration.

Gui Y.,East China Normal University | Gui Y.,Xianning College | Li W.,East China Normal University
Nonlinearity | Year: 2010

The well-known self-affine Sierpinski carpets, first studied by McMullen and Bedford independently, are constructed geometrically by repeating a single action according to a given pattern. In this paper, we extend them by randomly choosing a pattern from a set of patterns with different scales in each step of their construction process. The Hausdorff and box dimensions of the resulting limit sets are determined explicitly and the sufficient conditions for the corresponding Hausdorff measures to be positive finite are also obtained. © 2010 IOP Publishing Ltd and London Mathematical Society.

The effects of B2O3 on the sinter ability and microwave dielectric properties of Ca[(Li1/3Nb2/3) 0.92Zr0.08?δ?0.05TiO2 (CLNZ?0.05TiO 2) ceramics were investigated. B2O3 doping can effectively reduce sintering temperature by 150∼200 °C. The temperature coefficient of resonator frequency τfincreased with an increase of B2O3 content and sintering temperature. When B 2O3 of 2.5 wt % were added, the optimum microwave dielectric properties: εr =34.2, Qf =15680GHz and τf = ? 4.7×10?6/°C were obtained at the sintering temperature of 950 oC. ©(2012) Trans Tech Publications, Switzerland.

The effects of ZnO-B2O3-Na2O(ZBN) glass on the sinterability and microwave dielectric properties of Ca[(Li1/3Nb2/3)0.8Sn0.2]O3−δ−0.1TiO2 (CLNS−0.1TiO2) ceramics were investigated . ZBN glass doping can effectively reduce sintering temperatue by 100~150oC. The temperature coefficient of resonator frequency τf increased with an increase of ZBN glass content and sintering temperatue. When ZBN glass of 3wt% were added, the optimum microwave dielectric properties: εr =28.8,Qf =10960GHz and τf = − 7.5×10−6/oC were obtained at the sintering temperature of 1050oC. © (2011) Trans Tech Publications, Switzerland.

Xiong G.,Xianning College
Solid State Phenomena | Year: 2012

Crystal structure and microwave dielectric properties of Ca[(Li 1/3Nb2/3) 0.95Zr0.05]O 3?ωxTiO2(0x0.1) ceramics were investigated. A single phase with orthorhombic perovskite structure was obtained at x=0.02∼0.1. With an increasing of Ti4± content, the Qf value decreased due to a decrease of the degree of B-site 1:2 ordering. However, the τf value increased from-14.7ppm /oC to -6.9ppm/oC. When x=0.04, the optimum microwave dielectric properties: εr=31.1, Qf =21640GHz and τf =?8.8 ppm/oC. © (2012) Trans Tech Publications, Switzerland.

Discover hidden collaborations