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Burnaby, Canada

Patent
Xenon Pharmaceuticals Inc. | Date: 2014-10-09

This invention is directed to the (S)-enantiomer of the compound of formula (I): or a pharmaceutically acceptable solvate or prodrug thereof. This (S)-enantiomer is useful for the treatment of diseases or conditions, such as pain, which are ameliorated or alleviated by the modulation of voltage-gated sodium channels.


Patent
Xenon Pharmaceuticals Inc. | Date: 2013-03-11

This invention is directed to asymmetric syntheses of certain spiro-oxindole derivatives, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.


Patent
Genentech and Xenon Pharmaceuticals Inc. | Date: 2014-03-14

The invention provides compounds having the general formula (I): and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X


Patent
Xenon Pharmaceuticals Inc. | Date: 2014-05-07

This invention is directed to methods of preparing certain spiro-oxindole derivatives, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.


Patent
Novartis and Xenon Pharmaceuticals Inc. | Date: 2013-07-15

The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed.

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