Copenhagen, Denmark
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Patent
Xellia Pharmaceuticals Aps | Date: 2015-03-17

The present invention relates to new polymorphs consisting in crystallines solvates of Tiacumicin B, the solvates being propanol, isopropanol, acetic acid, isopropyl acetate, chlorobenzene and methyl-ethyl-ketone. The present invention also relates to a new amorphous form of Tiacumicin B.


Patent
Xellia Pharmaceuticals Aps | Date: 2014-01-09

Disclosed herein is a composition comprising at least one polymyxin or a salt thereof represented by formula (I) wherein R^(1 )is an aliphatic linear or branched C_(6)-C_(10 )acyl group, or (I) R^(5 )is CH(CH_(3))_(2), CH_(2)CH(CH_(3))_(2), CH(CH_(3))CH_(2)CH_(3), or CH_(2)C_(6)H_(5); R^(6 )is CH(CH_(3))_(2), CH_(2)CH(CH_(3))_(2), or CH(CH_(3))CH_(2)CH_(3); each of R^(2), R^(3), R^(4), R^(7 )and R^(8 )is either (CH_(2))_(X)CH_(2)NH_(2 )or (CH_(2))_(x)CH_(2)N(CH_(2)SO_(3)M)_(2); wherein x is 0 or 1; wherein M is a monovalent cation; and wherein at least three of R^(2), R^(3), R^(4), R^(7 )and R are (CH_(2))_(x)CH_(2)N(CH_(2)SO_(3)M)_(2).


The present invention concerns 2-amino-3-mmethyl-hex-5-enoic acid, its use for the production of peptides such as bacitracins and a method for producing it.


Patent
Xellia Pharmaceuticals ApS | Date: 2012-03-26

The present invention relates to an improved process for the preparation of Micafungin.


Patent
Xellia Pharmaceuticals ApS | Date: 2012-04-13

The present invention relates to a method for the purification of Micafungin.


Patent
Xellia Pharmaceuticals Aps | Date: 2014-01-09

The present invention relates to new voriconazole formulations comprising 2-hydroxypropyl--cyclodextrins and the preparation thereof.


Patent
Xellia Pharmaceuticals Aps | Date: 2014-11-19

The present invention relates to a composition comprising caspofungin or a pharmaceutical acceptable salt thereof and succinate or lactate as a buffering agent.


Patent
Xellia Pharmaceuticals Aps | Date: 2014-12-18

The present invention relates to the preparation of Tiacumicin B from a Dactylosporangium or Actinoplanes strain capable of producing Tiacumicin B utilizing spray drying and further extraction of the spray dried powder.


Patent
Xellia Pharmaceuticals ApS | Date: 2015-09-16

The present invention relates to a method for the purification of Micafungin.


The present invention regards a novel administration form and a novel administration regime useful in the treatment and prevention of a bacterial lung infection in patient in need thereof, in particular by providing a composition useful for aerosolization of a highly concentrated solution of aminoglycosides such as Tobramycin.

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