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Hsieh J.-Y.,Sudan University of Science and Technology | Hsieh J.-Y.,Minghsin University of Science and Technology | Chiang T.-Y.,National Cheng Kung University | Chen J.-L.,Wu Feng Institute of Technology | And 3 more authors.
Journal of Molecular Modeling | Year: 2011

Molecular dynamics simulations of the biphalin molecule, (Tyr-D-Ala-Gly-Phe-NH) 2, and the active tetrapeptide hydrazide, Tyr-D-Ala-Gly-Phe-NH-NH 2 were performed to investigate the cause of the increased μ and δ receptor binding affinities of the former over the latter. The simulation results demonstrate that the acylation of the two equal tetrapeptide fragments of biphalin produces the constrained hydrazide bridges {\hbox{C}}-4{\alpha } - {{\hbox{C}}-4}\prime - {{\hbox{N}}-9} - {{\hbox{N}}-{{10}}} and {{\hbox{N}}-9} - {{\hbox{N}}-{{10}}} - {{\hbox{C}}-5}\prime - {\hbox{C}}-5{\alpha } , which in turn increase the opportunity of conformations for binding to μ or δ receptors. Meanwhile, the connection of the two active tetrapeptide fragments of biphalin also results in the constrained side chain torsion angle χ 2 at one of the two residues Phe. This constrained side chain torsion angle not only significantly increases the δ receptor binding affinity but also makes most of the δ receptor binding conformations of biphalin bind to the δ receptor through the fragment containing the mentioned residue Phe. © 2010 Springer-Verlag. Source


Chia S.-H.,National Yunlin University of Science and Technology | Su K.-L.,National Yunlin University of Science and Technology | Shiau S.-V.,National Yunlin University of Science and Technology | Chien T.-L.,Wu Feng Institute of Technology
Artificial Life and Robotics | Year: 2011

This article describes a multilevel multisensor-based security system that has multiple interfaces to be applied in an intelligent home. The security system contains four levels. There is a passive detection level, an active detection level, a system supervising level, and a remote supervising level. The control unit of these passive modules is a HOLTEK microchip. Each passive module has two different interfaces (wireless RF and voice). These modules can use a voice to alarm users than an event has occurred, and can transmit the real-time status and image signal to the active detection level and the system's supervising level via the wireless RF interface. The active detection level can communicate with other levels via the wireless RF interface or the wireless Internet. The remote supervising level, the supervising level, and the active detection level can communicate with other levels via the wireless Internet. The status of these modules can also be displayed on the monitor of the supervising computer. Finally, we present some experimental results using passive and active detection modules in the security system. © ISAROB 2011. Source


Liu Y.-C.,Wu Feng Institute of Technology | Fu Y.-P.,National Dong Hwa University
Ceramics International | Year: 2010

Copper ferrite nanopowders were successfully synthesized by a microwave-induced combustion process using copper nitrate, iron nitrate, and urea. The process only took a few minutes to obtain CuFe2O 4 nanopowders. The resultant powders were investigated by XRD, SEM, VSM, and surface area measurement. The results revealed that the CuFe 2O4 powders showed that the average particle size ranged from 300 to 600 nm. Also, it possessed a saturation magnetization of 21.16 emu/g, and an intrinsic coercive force of 600.84 Oe, whereas, upon annealing at 800 °C for 1 h. The CuFe2O4 powders specific surface area was 5.60 m2/g. Moreover, these copper ferrite magnetic nanopowders also acted as a catalyst for the oxidation of 2,3,6-trimethylphenol to synthesize 2,3,5-trimethylhydrogenquinone and 2,3,5-trimethyl-1,4- benzoquinone for the first time. On the basis of experimental evidence, a rational reaction mechanism is proposed to explain the results satisfactorily. © 2010 Elsevier Ltd and Techna Group S.r.l. All rights reserved. Source


Chia S.-H.,Wu Feng Institute of Technology | Su K.-L.,Sudan University of Science and Technology | Guo J.-H.,Sudan University of Science and Technology | Chung C.-Y.,Sudan University of Science and Technology
Proceedings - 4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010 | Year: 2010

Ant colony optimization (ACO) is a new evolvement algorithm that is proposed by Dorigo M., and solves some task allocation and target search problems to program the motion path searching food. The topic of the article uses the ant colony optimization algorithm to mobile robot system, and solve the problem of mobile robot path planning such that the target point in a collision free space. The simulated results presents that ACO can finds the optimization motion path for mobile robot moving to the target position (food) from the start position (nest) in a collision-free environment. © 2010 IEEE. Source


Chi J.-H.,Wu Feng Institute of Technology | Wu S.-H.,National Yunlin University of Science and Technology | Shu C.-M.,National Yunlin University of Science and Technology
Simulation Modelling Practice and Theory | Year: 2011

Statistical data over the past 24 years detailing the number of fires and building floor areas published by the Taiwan government was employed to determine the fire probability, frequency, and cycle for each building category. By applying a matrix calculation, the fire probability, frequency, cycle, and risk ratio for each functional area within a multi-purpose building were obtained. With assistance from the Taiwan government, the fire case investigation and statistical data for building fires were established. By adopting the risk ratio concept, the weight values for 20 fire safety assessment criteria and 4 fire safety strategies for a multi-purpose building were acquired to indicate the possible causes of fires and the quantitative extent of fire influence. © 2010 Elsevier B.V. All rights reserved. Source

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