Time filter

Source Type

Wanju, South Korea

Woosuk University is a university located in Wanju-gun, North Jeolla, South Korea. Wikipedia.

Oh D.Y.,University of California at San Diego | Morinaga H.,University of California at San Diego | Talukdar S.,University of California at San Diego | Bae E.J.,Woosuk University | Olefsky J.M.,University of California at San Diego

Macrophage-mediated inflammation is a key component of insulin resistance; however, the initial events of monocyte migration to become tissue macrophages remain poorly understood. We report a new method to quantitate in vivo macrophage tracking (i.e., blood monocytes from donor mice) labeled ex vivo with fluorescent PKH26 dye and injected into recipient mice. Labeled monocytes appear as adipose, liver, and splenic macrophages, peaking in 1-2 days. When CCR2 KO monocytes are injected into wild-type (WT) recipients, or WT monocytes given to MCP-1 KO recipients, adipose tissue macrophage (ATM) accumulation is reduced by ∼40%, whereas hepatic macrophage content is decreased by ∼80%. Using WT donor cells, ATM accumulation is several-fold greater in obese recipient mice compared with lean mice, regardless of the source of donor monocytes. After their appearance in adipose tissue, ATMs progressively polarize from the M2- to the M1-like state in obesity. In summary, the CCR2/MCP-1 system is a contributory factor to monocyte migration into adipose tissue and is the dominant signal controlling the appearance of recruited macrophages in the liver. Monocytes from obese mice are not programmed to become inflammatory ATMs but rather the increased proinflammatory ATM accumulation in obesity is in response to tissue signals. © 2012 by the American Diabetes Association. Source

Bae J.,Korea Institute for Advanced Study | Hwang W.-Y.,Chonnam National University | Han Y.-D.,Woosuk University
Physical Review Letters

We provide a general framework of utilizing the no-signaling principle in derivation of the guessing probability in the minimum-error quantum state discrimination. We show that, remarkably, the guessing probability can be determined by the no-signaling principle. This is shown by proving that, in the semidefinite programing for the discrimination, the optimality condition corresponds to the constraint that quantum theory cannot be used for a superluminal communication. Finally, a general bound to the guessing probability is presented in a closed form. © 2011 American Physical Society. Source

Effects of green tea catechin (GTC, catechin content 61. 4%) on the formations of hydroperoxide, malonaldehyde, and volatile compounds, and losses of retinol and tocopherol in milk during light illumination were studied. GTC showed surprisingly high protective activity of milk photooxidation, in a dose dependent manner. GTC at 25 ppm exerted 82. 1 and 75. 0% inhibitions of hydroperoxide and malonaldehyde formation during 30 h light illumination, respectively. GTC at 25 ppm exerted 88. 7 and 94. 3% inhibition of hexanal and heptanal formation in milk during 30 h light illumination, respectively. The 25 ppm GTC greatly suppressed the losses of retinol and α-tocopherol, showing 53. 6 and 58. 7% protections of their losses in milk after 12 h light illumination, respectively. The protective activity of GTC was at least 4 times higher than ascorbic acid. The inhibitory activities of GTC and ascorbic acid against the photooxidation of milk were in consistent with their singlet oxygen quenching abilities. © 2011 The Korean Society of Food Science and Technology and Springer Netherlands. Source

Smoke affects fire detection and visibility as well as the number of fire victims through inhalation. The size distributions of smoke particles are prerequisites for understanding the characteristics of fire smoke. The purpose of this work is to find the characteristics for the development of the size distribution of smoke particles in a compartment fire. In this work, the dynamic equation for the discrete-size spectrum of particles was solved using the nodal method. The collision frequency function for the entire regime, reflecting the fractal dimension of the particles, was applied. The results were presented for each variation of the parameters such as the history of the heat release rate, smoke yield, and the size of primary particles. © 2011 Elsevier Ltd. All rights reserved. Source

Park J.-J.,Joongbu University | Lee J.-Y.,Woosuk University
IEEE Transactions on Dielectrics and Electrical Insulation

A new electric application method was developed to prepare epoxy/organoclay nanocomposite for the electrical insulation in the ac electric fields and it could be also used in the field of various viscous polymer/organoclay systems. The applied ac electric field condition was as follows; (1) inter-electrode distance: 40 mm, (2) application voltage: 3-11 kV, (3) frequency: 60-1,000 Hz, and (4) application time: 0-60 min. To characterize the epoxy/clay nanocomposite, WAXS and TEM analyses were performed. In order to explain how the organic modifier affects the exfoliation phenomena, a mechanism of the oscillating collision of the quaternary ammonium head was proposed and the effects of the ac voltage and frequency and the organoclay content were studied. © 2010 IEEE. Source

Discover hidden collaborations