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Grant
Agency: Cordis | Branch: FP7 | Program: NoE | Phase: Fission-2009-3.1.1 | Award Amount: 21.29M | Year: 2010

The aim of DoReMi is to promote the sustainable integration of low dose risk research in Europe in order to aid the effective resolution of the key policy questions identified by the High Level Expert Group (HLEG) on Low Dose Risk Research (www.hleg.de). DoReMi provides an operational tool for the development of the proposed MELODI platform (Multidisciplinary European Low Dose Risk Re-search Initiative) consisting of major national bodies and research programmes that have long term commitment in low dose risk research in Europe. A Letter of Intent between the core members of MELODI has been signed in April 2009. During the project, new members are expected to join the Initiative. The Joint Programme of Activities (JPA) of DoReMi includes: (i) a Joint Programme of Research (JPR) covering the issues outlined above and providing an overview of the needs for research infra-structures of pan-European interest and facilitating multilateral initiatives leading to better use and development of research infrastructures; (ii) a Joint Programme of Integration (JPI) to develop a coor-dinated European roadmap for the long term needs of the key players in Europe; and (iii) a Joint Pro-gramme for the Spreading of Excellence (JPSE), covering knowledge management, training and mo-bility and its implementation. The JPR focuses on the areas identified by the HLEG as the most prom-ising in terms of addressing/resolving the key policy questions, namely: the shape of dose response curve for cancer, individual susceptibilities and non-cancer effects. Radiation quality, tissue sensitivity and internal exposures will be addressed as cross cutting themes within the three main research areas. A substantial proportion of the JPA will be dedicated to the joint programme of research. The pro-gramme describes a multidisciplinary approach including interfaces with the broader biological toxico-logical and epidemiological communities. Strategic planning will be carried out in close collaboration with MELODI. The long term Strategic Research Agenda (SRA) will be developed by MELODI, whereas DoReMi research priorities are based on a shorter term Transitional Research Agenda (TRA), focusing on goals that are feasible to achieve within the 6 year project and areas where barriers need to be removed in order to proceed with the longer term strategic objectives.


Grant
Agency: Cordis | Branch: FP7 | Program: CP-FP | Phase: SEC-2013.1.3-1 | Award Amount: 4.43M | Year: 2014

The objectives of the EXPEDIA project are both to inhibit some frequently used explosive precursors and to increase the knowledge about garage chemistry. With this we mean, increasing the understanding of how terrorists create homemade explosives (HME), what chemicals they start from and where they find them in the open market. But also, to increase the understanding of how easily a HME can be created, what basic equipment is necessary and what chemical knowledge is needed by the terrorist. The output from EXPEDIA will increase the security of the citizens in Europe both in the sense that chemical inhibition will reduce/ limit or at least make it much harder for terrorists to create HMEs from readily available chemicals. Understanding the terrorist perspective regarding HME production, will directly give input to both first responders and European legislators. As one of the output EXPEDIA will create A European guide for first responders with basic instructions on how to interpret findings on a crime scene when suspected bomb factories have been encountered. In order for European legislators to carry out right work in the fight against terrorism, access to accurate data and an in-depth understanding of the characteristics of HMEs and various formulations thereof is of crucial importance. EXPEDIA will feed its produced information about HMEs directly to these groups via appropriate channels. Finally, EXPEDIA will research for solutions to prevent the misuse of some explosive precursors that have not yet been investigated within the FP7 research programme. The inhibition of these precursors will be closely linked to feasibility and implementation cost studies as well as to toxicology studies. The solutions should be environmentally friendly and economically defendable in order to be able to be implemented into precursors that are produced in large quantities today.


Grant
Agency: Cordis | Branch: FP7 | Program: CP | Phase: SEC-2009-1.3-03 | Award Amount: 4.30M | Year: 2010

Homemade explosives (HMEs) are easy to make from readily available materials used for legitimate purposes in everyday life. This availability attracts terrorists to manufacture and use homemade explosives since military and commercial explosives are harder to come by. Two approaches to improve this situation exists. 1) Prohibit or limit the accessibility of these precursor chemicals 2) Use science to solve this problem by making it harder for potential terrorists to make HMEs or by facilitating the detection of these. PREVAIL will address these scientific challenges by a novel approach. The PREVAIL concept and objectives are to prevent the use of hydrogen peroxide (HP) and acetone as precursors to homemade explosives by the development of a series of novel inhibitors, and to ensure that the detection of ammonium nitrate (AN) based devices is facilitated by adding markers tailored to a very sensitive detection system. These objectives must be met without obstructing the legitimate use or causing any adverse effects on the environment or peoples health. The PREVAIL project main activities are development and testing of markers for the inhibition of TATP production and for the concentration of HP by boiling off water (as was done for the London bombings) as well as development of novel markers for easy detection of illicit use of fertilizers. The final outcome of the PREVAIL project are inhibitors for illicit production of TATP and HP based explosives as well as novel marker/detector systems for easy detection of AN based bombs. The PREVAIL project will work together with the chemical manufacturing industry in order to achieve early industrial acceptance of the research. The PREVAIL consortium consists of four research institutes (FOI, TNO,CEA, WIHiE), two chemical industries representing the End Users (Yara, Arkema), three SMEs (Inscentinel, KCEM, SECRAB) and one university (Technion).


Kieliszek J.,Wojskowy Instytut Higieny i Epidemiologii | Sobiech J.,Wojskowy Instytut Higieny i Epidemiologii | Stankiewicz W.,Wojskowy Instytut Higieny i Epidemiologii | Rongies W.,Medical University of Warsaw
Przeglad Elektrotechniczny | Year: 2010

In this paper the results of measurements of electric field strength distribution in the near field region of medical devices and manpack radio antennas has been presented. Also the results of measurements of currents inducted in the body operators and results of computations of these currents has been compared. The applicability for health risk assessment of computations of SAR and inducted in human body currents has been discussed.


Grant
Agency: Cordis | Branch: FP7 | Program: MC-IRSES | Phase: FP7-PEOPLE-2013-IRSES | Award Amount: 228.00K | Year: 2014

Anthrax, caused by the spore forming bacterium Bacillus anthracis, is a disease of animals which can infect humans either directly through contact with infected animals or indirectly as a consequence of bioterrorism. In regions of the world such as Eastern Europe and Central Asia the pathogen still constitutes a significant threat to human and animal health. A lack of effective veterinary facilities, access to vaccines and the burial of untreated infected animals has resulted in the contamination of large areas due to the ability of the spores to survive in soil for many years. Given that the bacteria is non-contagious its elimination from contaminated soil and surfaces would have a major impact on disease incidence. We are seeking to to develop an approach which is specific for B.anthracis and will have minimal impact on the environment. Following preliminary field trails on animal burial sites in Turkey we have developed a technique whch triggers the conversion (germination) of B.anthracis spores into bacteriophage (phage) susceptible vegetative bacteria. Phages are natural preditors of bacteria, are species specific and found in close proximity to their prey. We hypothesize that a combination of germinants and B.anthracis specific phages will be an effective and ecologically friends means of reducing spore numbers. Indeed in laboratory studies we have demonstrated the feasibility of this approach. Additional phages have been isolated from burial sites in Georgia and Turkey and will be evaluated as part of this study. While there are a number of funded phage based anthrax decon projects in the region their is as yet no dedicated scientific network to facilitate the sharing of best practices and to link researchers in neighbouring countries facing similar problems. It is our intention to link these projects together in a manner which maximises the current investment and will deliver an environmentally friendly decontamination system.


Stankiewicz W.,Wojskowy Instytut Higieny i Epidemiologii | Stasiak-Barmuta A.,Medical University of Bialystok
Polski Merkuriusz Lekarski | Year: 2011

The immune system theory of aging is that the rate of aging is largely controlled by the immune system. As we age, the numbers of critical cells in the immune system decrease and become less functional. Accumulating data are documenting an inverse relationship between immune status, response to health, and longevity, suggesting that the immune system becomes less effective with advancing age and that this is clinically relevant. The mechanisms and consequences of age-associated immune alterations are briefly reviewed here.


Kolodziej M.,Wojskowy Instytut Higieny i Epidemiologii
Przegla̧d epidemiologiczny | Year: 2011

The efficiency of peptides against many species of bacteria, fungi and parasites has been widely described. Recent studies on peptides have also demonstrated their antiviral activity. Some peptides exhibit direct virucidal activity, others disturb attachment of virus particles to the cell membrane surface or interfere with intracellular replication of virus. Due to limited effectiveness of commonly used drugs and emerging resistance of viruses, antiviral peptides may have the potential to be developed as putative therapeutic agents.


Korzeniewska E.,Technical University of Lodz | Duraj A.,Technical University of Lodz | Krawczyk A.,Wojskowy Instytut Higieny i Epidemiologii | Krawczyk A.,Czestochowa University of Technology
Przeglad Elektrotechniczny | Year: 2013

The following article presents results of research related to the application of vacuum technology used in the manufacture of electrodes for electrical stimulation and monitoring of physiological parameters. Pointed to the ability to detect discrepancies between the actual and the processed signal with the device to collect information about the health of the patient. In this study, the authors examined the adequacy of algorithms of the description to the real course of phenomena.


Sobiech J.,Wojskowy Instytut Higieny i Epidemiologii | Kieliszek J.,Wojskowy Instytut Higieny i Epidemiologii | Puta R.,Wojskowy Instytut Higieny i Epidemiologii | Bodera P.,Wojskowy Instytut Higieny i Epidemiologii | Stankiewicz W.,Wojskowy Instytut Higieny i Epidemiologii
Przeglad Elektrotechniczny | Year: 2012

The protective properties of clothing, that is used to protect workers against the strong electromagnetic field, are specified by measurement of the electromagnetic shielding provided by clothing in the standard test system. In the described method the electric field is measured inside the lossy phantom and inside this phantom when is placed inside the protective suit. The correctness of the measurement depends on the phantom structure. This work concerns matching of the dielectric properties of the phantom lossy medium.


PubMed | Wojskowy Instytut Higieny i Epidemiologii
Type: Journal Article | Journal: Przeglad epidemiologiczny | Year: 2011

The efficiency of peptides against many species of bacteria, fungi and parasites has been widely described. Recent studies on peptides have also demonstrated their antiviral activity. Some peptides exhibit direct virucidal activity, others disturb attachment of virus particles to the cell membrane surface or interfere with intracellular replication of virus. Due to limited effectiveness of commonly used drugs and emerging resistance of viruses, antiviral peptides may have the potential to be developed as putative therapeutic agents.

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