Wiwanitkit House

Bangkok, Thailand

Wiwanitkit House

Bangkok, Thailand

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Wiwanitkit V.,Wiwanitkit House
Journal of Medical Case Reports | Year: 2011

Emerging infectious diseases are an important problem in medicine. Case reports usually document episodes in the early emerging phase or in a small outbreak. Although the case report is considered weak evidence in medical literature, it is usually the first report when there is a new emerging infectious disease. There is no doubt that case reports can provide useful information for further case series, reviews and studies. This editorial focuses on the usefulness of the case report on emerging infectious disease to the medical society. Publication in this area is highly welcomed by the journal and can serve as a future point of reference. © 2011 Wiwanitkit; licensee BioMed Central Ltd.


Wiwanitkit V.,Wiwanitkit House
Annals of Indian Academy of Neurology | Year: 2013

Alzheimer's disease is a common kind of dementia. This disorder can be detected in all countries around the world. This neurological disorder affects millions of population and becomes an important concern in modern neurology. There are many researches on the pathogenesis of Alzheimer's disease. Although it has been determined for a long time, there is no clear-cut that this is a case with genetic disorder or not. A physiological genomics is a new application that is useful for track function to genes within the human genome and can be applied for answering the problem of underlying pathobiology of complex diseases. The physiogenomics can be helpful for study of systemic approach on the pathophysiology, and genomics might provide useful information to better understand the pathogenesis of Alzheimer's disease. The present advent in genomics technique makes it possible to trace for the underlying genomics of disease. In this work, physiological genomics analysis for Alzheimer's disease was performed. The standard published technique is used for assessment. According to this work, there are 20 identified physiogenomics relationship on several chromosomes. Considering the results, the HADH2 gene on chromosome X, APBA1 gene on chromosome 9, AGER gene on chromosome 6, GSK3B gene on chromosome 3, CDKHR1 gene on chromosome 17, APPBP1 gene on chromosome 16, APBA2 gene on chromosome 15, GAL gene on chromosome 11, and APLP2 gene on chromosome 11 have the highest physiogenomics score (9.26) while the CASP3 gene on chromosome 4 and the SNCA gene on chromosome 4 have the lowest physiogenomics score (7.44). The results from this study confirm that Alzheimer's disease has a polygenomic origin. © 2013 Annals of Indian Academy of Neurology.


Wiwanitkit V.,Wiwanitkit House
Expert Review of Anti-Infective Therapy | Year: 2010

Dengue fever is a common tropical infection. This acute febrile illness can be a deadly infection in cases of severe manifestation, causing dengue hemorrhagic shock. In this brief article, I will summarize and discuss the diagnosis and treatment of this disease. For diagnosis of dengue, most tropical doctors make use of presumptive diagnosis; however, the definite diagnosis should be based on immunodiagnosis or viral study. Focusing on treatment, symptomatic and supportive treatment is the main therapeutic approach. The role of antiviral drugs in the treatment of dengue fever has been limited, but is currently widely studied. © 2010 Expert Reviews Ltd.


Wiwanitkit V.,Wiwanitkit House
Indian Journal of Medical and Paediatric Oncology | Year: 2013

Background: Ovarian tumor is a cause of infertility in the fertile-aged women. Also, it can also turns into malignancy and causes deadly outcome. Screening for malignancy is an important management. Aims: The available screening methods that are widely used at present include CA-125 determination and the risk of malignancy index (RMX), which is a combined CA-125 with ultrasonography, determination. Materials and Methods: Here, the author tries to assess cost-effectiveness of both alternative in screening by basic medical economics technique. Statistics: Classical descriptive analysis was used for cost effectiveness calculation. Results: In this work, from the cost-effectiveness analysis, the CA-125 test is more cost-effectiveness than RMX. Conclusion: This reflects that the usage of additional ultrasonography test for increasing the diagnostic activity in screening for ovarian cyst in the fertile aged females in Thailand is still not appropriate.


Wiwanitkit V.,Wiwanitkit House
Journal of Infection in Developing Countries | Year: 2010

Dengue is the most important tropical mosquito-borne infectious disease caused by an arbovirus, the dengue virus. It should be noted that there are still other unusual modes of transmission of dengue infection. This paper summarizes those non vector-borne transmissions of dengue including vertical transmission, transfusion related transmission, transplantation related transmission, and needle-stick-related transmission. Copyright © 2010 Wiwanitkit et al.


Wiwanitkit V.,Wiwanitkit House
Asian Pacific Journal of Tropical Biomedicine | Year: 2011

There are several tropical mosquito borne infections. Malaria and dengue are the two common mosquito infections that are very important and cause high morbidity and mortality for many patients around the world. Concurrent malaria and dengue infection is an important condition that is seldom reported. In this specific article, the author hereby summarizes on the topic of concurrent malaria and dengue infection. © 2011 Asian Pacific Tropical Biomedical Magazine.


Wiwanitkit V.,Wiwanitkit House
Journal of Cancer Research and Therapeutics | Year: 2011

Background: Hepatitis C virus is a common virus affecting human health. High rates of hepatitis C virus infection can be seen in many developing countries. It is accepted that hepatitis C virus is an oncogenic virus that can lead to liver cancer. Some recent researches also mentioned the possibility of hepatitis C virus as a risk for renal cell carcinoma. Aims: In this article, the author assesses the cause-outcome relationship between hepatitis C virus infection and renal cell carcinoma using the bioinformatics network analysis technique. Materials and Methods: The author firstly tracked for the hepatitis C virus related protein and renal cell carcinoma related protein and further detected the common protein. Further, tracing of the biological process using ontology study of the identified proteins was done and finalized network of relationship was derived. Statistical Analysis Used: Bioinformatics technique. Results and Conclusions: According to this study, there is only one common protein. Based on this work, it can be concluded that there might be cause-outcome relationship between hepatitis C virus infection and renal cell carcinoma via NY-REN-54. The process might be through the disturbance of autophagic response due to ubiquitin-protein ligase-related mechanism.


Wiwanitkit V.,Wiwanitkit House
Asian Pacific Journal of Cancer Prevention | Year: 2010

Gastric cancer is an important gastrointestinal carcinoma. Presently, it is accepted that the strongest etiological relationship is with Helicobacter pylori infection. Screening for the bacterium thus becomes an issue for discussion in gastric cancer prevention. Here, the author covers the use of H. pylori screening as a strategy based on an economical analysis in the scenario of a tropical developing country.


Wiwanitkit V.,Wiwanitkit House
Rural and Remote Health | Year: 2011

Context: Throughout its history, the main problem for Thailand's health system has been an inadequate number of physicians and other healthcare workers in rural areas. Due to this, for decades in Thailand, rural service has been mandatory for healthcare workers. Issue: Thailand's mandatory health service system commenced in 1889 and has been continuous until the present (2010). Under this system, all early-career health workers from public professional schools serve in rural areas as a governmental worker to maintain the rural health workforce. The system has ameliorated the shortage of physicians in rural areas by substantially decreasing the emigration of Thai physicians to foreign countries. Recently, an increasing number of healthcare workers have been streamed from mandatory rural service to urban private hospitals, leaving the mandatory rural service system at risk. This has led to a deterioration of shortage of rural healthcare workers. A number of strategies have been implemented in an attempt to solve this problem, such as one-year rural service prerequisite for specialist training for all new medical graduates; a special program in medical schools to produce rural physicians; setting a special salary rate for rural physicians; and founding new medical schools in rural areas. Lessons learned: Thai mandatory rural health service has succeeded in ameliorating the shortage of rural health workers although it has its own limitations and problems. In order to maintain effectiveness, the system requires continuous amendments in response to rapid changes in the medical and economic landscape in Thailand. © V Wiwanitkit, 2011.


Wiwanitkit V.,Wiwanitkit House
North American Journal of Medical Sciences | Year: 2013

Influenza virus infection is a common respiratory pathogen. Emerging of new atypical influenza is usually a big public health threat. H7N9 bird flu is the newest atypical influenza virus infection that has just been reported since early 2013. The emerging of this new disease occurred in China and becomes the present focus for possible worldwide pandemic. In this specific article, the author will discus and describe on epidemiology, symptomatology, pathology, diagnosis, treatment, and prevention of this new bird flu. The literature researching by PubMed and Google is used for data gathering in this collective review.

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