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Winona, MN, United States

Winona State University is a public university in Winona, Minnesota, United States, with approximately nine thousand enrolled undergraduate and graduate students. Winona State University is the oldest member of the Minnesota State Colleges and Universities System, the fifth-largest system of two- and four-year colleges and universities in the country, based on student enrollment. WSU offers more than 80 programs on its main campus, as well as select programs on its satellite Winona, West Campus and Winona State University—Rochester. Wikipedia.

Valen M.S.,Winona State University
Journal of cultural diversity | Year: 2012

Type 2 diabetes disproportionately affects the Hispanic population. New approaches are needed to provide effective education to this population. This evidence-based project utilized community health workers (CHWs) to deliver a culturally relevant diabetes education program to a Hispanic population at a migrant clinic. The program emphasized culturally relevant interventions to improve self-efficacy. Formative evaluation was used to develop and improve the program. Participants showed improvement in diabetes knowledge and diabetes related self-efficacy scores. Outcomes also included improvement in CHWs' diabetes knowledge and development of an educational program that could be utilized in other settings serving Hispanic populations with type 2 diabetes. Source

Townsend R.E.,Winona State University
Australian Journal of Agricultural and Resource Economics | Year: 2010

When faced with opportunities for greater self-governance, the New Zealand fishing industry managed to make only limited progress. Why industry was unable to progress self-management more effectively remains an interesting question. This paper argues that the benefits of greater self-governance were probably less than the significant transactions costs to self-organise. The benefits were probably smaller in New Zealand than elsewhere, because reform had already reduced the costs of fisheries administration. And the transactions costs confronting industry were substantial. First, unanimous agreement was required for self-governance, which created high transactions costs. Second, the tools for private enforcement were limited. Third, policy failed to specify clearly the expectations of self-governance, so the investments in self-governance are unusually risky. The government had unrealistic expectations that self-governance would solve third-party environmental externalities as well as fishing externalities. This implied high transactions costs to negotiate with third parties, such as environmental groups. Fourth, the standards for accountability were difficult to specify. This experience identifies four key policies if devolved fisheries governance is to be promoted: non-unanimous decision-making; private enforcement; clarity on areas for self-governance; and clarity on accountability standards. © 2010 The Author. Journal compilation © 2010 Australian Agricultural and Resource Economics Society Inc. and Blackwell Publishing Asia Pty Ltd. Source

Yen B.,Mount Sinai School of Medicine | Mulder L.C.F.,Mount Sinai School of Medicine | Martinez O.,Winona State University | Basler C.F.,Mount Sinai School of Medicine
Journal of Virology | Year: 2014

Zaire ebolavirus (EBOV) VP35 is a double-stranded RNA (dsRNA)-binding protein that inhibits RIG-I signaling and alpha/beta interferon (IFN-α/β) responses by both dsRNA-binding-dependent and -independent mechanisms. VP35 also suppresses dendritic cell (DC) maturation. Here, we define the pathways and mechanisms through which VP35 impairs DC maturation. Wildtype VP35 (VP35-WT) and two well-characterized VP35 mutants (F239A and R322A) that independently ablate dsRNA binding and RIG-I inhibition were delivered to primary human monocyte-derived DCs (MDDCs) using a lentivirus-based expression system. VP35-WT suppressed not only IFN-α/β but also proinflammatory responses following stimulation of MDDCs with activators of RIG-I-like receptor (RLR) signaling, including RIG-I activators such as Sendai virus (SeV) or 5'-triphosphate RNA, or MDA5 activators such as encephalomyocarditis virus (EMCV) or poly(I·C). The F239A and R322A mutants exhibited greatly reduced suppression of IFN-α/β and proinflammatory cytokine production following treatment of DCs with RLR agonists. VP35-WT also blocked the upregulation of DC maturation markers and the stimulation of allogeneic T cell responses upon SeV infection, whereas the mutants did not. In contrast to the RLR activators, VP35-WT and the VP35 mutants impaired IFN-β production induced by Toll-like receptor 3 (TLR3) or TLR4 agonists but failed to inhibit proinflammatory cytokine production induced by TLR2, TLR3, or TLR4 agonists. Furthermore, VP35 did not prevent lipopolysaccharide (LPS)-induced upregulation of surface markers of MDDC maturation and did not prevent LPS-triggered allogeneic T cell stimulation. Therefore, VP35 is a general antagonist of DC responses to RLR activation. However, TLR agonists can circumvent many of the inhibitory effects of VP35. Therefore, it may be possible to counteract EBOV immune evasion by using treatments that bypass the VP35-imposed block to DC maturation. © 2014, American Society for Microbiology. Source

Anderson D.E.,Winona State University
Journal of Strength and Conditioning Research | Year: 2010

The purpose of this study was to examine the impact of nutritional feedback on dietary intake and body composition of college women volleyball players. Eight members of an National Collegiate Athletic Association (NCAA) division II women's volleyball team participated as subjects. Three-day diet records and body composition (via air displacement plethysmography) were analyzed at the beginning of the season (Beginning), peak training during the season (Peak), and 1 week postseason (After). During the first season (Baseline), the athletes were given no information concerning their dietary intakes. In the following year (Feedback), athletes were given information with regard to dietary intakes of themselves and the team as a whole. Percent body fat was not significantly different between Baseline and Feedback trials. During Beginning and Peak, the mean energy intakes ranged from 35.3 to 40.8 kcal·kg -1·bw -1. Protein intake was significantly greater in Feedback-Beginning (1.5 ± 0.9 g·kg -1·bw -1) compared to Baseline-Beginning (1.1 ± 0.1 g·kg -1·bw -1). No significant differences were seen in Baseline vs. Feedback for either carbohydrate or fat intakes. The only vitamin with significantly different consumption was vitamin C, with intakes of Feedback-Beginning (303.8 ± 99.8% Dietary Reference Intakes [DRI]) vs. Baseline-Beginning (115.3 ± 32.3% DRI). A significantly greater amount of calcium was consumed at Feedback-Beginning (152.0 ± 25.2% DRI) compared to Baseline-Beginning (102.2 ± 21.2% DRI). In conclusion, dietary feedback resulted in increased intake of protein, vitamin C, and calcium at the beginning of the season only for female collegiate volleyball players. Other than an increase in fiber, dietary intake at the peak of the season and postseason was not influenced by feedback. Body composition was unaffected by feedback at Beginning, Peak, and After. © 2010 National Strength and Conditioning Association. Source

Park J.H.,University of Texas at Austin | Park J.H.,Chonbuk National University | Thorgaard S.N.,University of Texas at Austin | Thorgaard S.N.,Winona State University | And 2 more authors.
Journal of the American Chemical Society | Year: 2013

We describe the electrochemical detection of single nanoparticle (NP) attachment on a nanoelectrode by the increase in the active electrode area. The attachment of gold NP-decorated single wall carbon nanotubes (Au-SWCNTs) was observed by their current-time transients for ferrocenemethanol (FcMeOH) oxidation. Since the attached Au-SWCNT increases the electroactive area available for FcMeOH oxidation, the current increases after attachment of the particle. The "staircase" shape of the current response establishes that the particles do not become deactivated for the outer-sphere electron transfer reaction after attachment. Au-SWCNTs migrate to and are held at the nanoelectrode by an electric field. However, SWCNTs that are not decorated with a gold NP produce only a sharp transient ("blip") response. © 2013 American Chemical Society. Source

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