Deforest D.K.,Windward |
Van Genderen E.J.,ZINC Inc
Environmental Toxicology and Chemistry | Year: 2012
The United States Environmental Protection Agency's (U.S. EPA) current ambient water quality criteria (AWQC) for zinc in freshwater are hardness-based and were last updated in 1995. The acute and chronic freshwater toxicity databases have since expanded substantially and the U.S. EPA's minimum phylogenetic diversity requirements for chronic zinc toxicity are now met (an acute:chronic ratio was previously required). Additionally, several acute and chronic biotic ligand models (BLMs) for zinc have since been developed and validated for freshwater organisms. Using the expanded toxicity database and existing BLMs, we developed a unified zinc BLM that could efficiently predict both acute and chronic toxicity over a wide range of zinc bioavailabilities. The unified BLM, developed by objectively averaging the biotic ligand binding constants for zinc (Zn2+) and competing cations (Ca2+, Mg2+, Na+, H+) from existing BLMs, performed better in predicting toxicity to a diverse set of organisms than any individual existing BLM. Performance of the unified BLM was further improved by optimizing the biotic ligand binding constant for the ZnOH+ species. The updated freshwater zinc toxicity database and unified BLM were then used to estimate the fifth percentiles of the acute and chronic species sensitivity distributions following the U.S. EPA guidelines for AWQC development. © 2012 SETAC.
Journal of Child and Adolescent Psychiatric Nursing | Year: 2011
TOPIC: Because of the link between communication impairments and psychiatric disorders, it is important for nurses and other healthcare professionals to know the warning signs for the need for a communication/speech/language evaluation for children during infancy through early childhood. PURPOSE: This article presents an overview of the role of speech-language pathologists (SLPs); the expected developmental achievements for youngsters from infancy to age 5 in speech, language, and communication; and the clinically significant warning signs that indicate a need for speech/language assessment. SOURCES: Sources for this article included published literature on the topic along with the clinical judgment and expertise of the author, a certified SLP. CONCLUSIONS: Warning signs for referral to an SLP may be subtle and may present in developmental, academic, behavioral, or social-emotional realms. Collaboration between nurses and communication professionals will allow for early identification and intervention. Early detection of speech and language disabilities is key to maximizing the effects of early intervention, resulting in more positive communication outcomes in later life. It has been found that speech and language delays and disorders, with symptoms left untreated, can cause difficulties in learning and socialization that can last into adolescence and beyond. Early identification of children with developmental delay or developmental disabilities may lead to intervention at a young age when chances for improvement may be best. © 2011 Wiley Periodicals, Inc.
Integrated environmental assessment and management | Year: 2013
In Europe, the European Union's Existing Substances Regulation (EEC 793/93), the REACH Regulation, and Water Framework Directive all share common guidance for conducting environmental effects assessments, which can be further used to derive predicted no effect concentrations (PNECs) and environmental quality standards (EQS) for chemical substances. To meet the criteria for using a species sensitivity distribution (SSD) in the effects assessment of Ni for marine organisms, chronic toxicity data from the published scientific literature were augmented with toxicity testing of several additional marine species including: a unicellular alga (Dunalliela tertiolecta), a diatom (Skeletonema costatum), 2 macroalgae (Champia parvula, Macrocystis pyrifera), 2 mollusks (Crassostrea gigas, Mytilus galloprovincialis), 2 echinoderms (Dendraster excentricus, Strongylocentrotus purpuratus), a polychaete (Neanthes arenaceodentata), and a fish (Cyprinodon variegatus). Based on this updated database, which includes chronic Ni toxicity data for a total of 17 marine species, HC5 values (hazardous concentrations to 5% of the species) were derived using an SSD. The most sensitive species is a tropical sea urchin from the Caribbean region, Diadema antillarum, which has an EC10 that is approximately 6-fold less than the EC10 for the second most sensitive species tested. There is some uncertainty in the representativeness of D. antillarum to temperate European marine waters because 1) a European sea urchin species (Paracentrotus lividus) is approximately 48-fold less sensitive to Ni, and (2) ambient marine Ni concentrations in at least some European waters closely approach the D. antillarum EC10. The HC5 values with and without D. antillarum included in the SSD are 3.9 and 20.9 μg/L, respectively. Site-specific toxicity testing with local species may be warranted for locations where Ni concentrations fall between the range in HC5s of 3.9 to 20.9 μg/L. © 2013 SETAC.
Agency: GTR | Branch: Innovate UK | Program: | Phase: Innovation Voucher | Award Amount: 5.00K | Year: 2015
Windward | Date: 2013-07-03
A method of providing a comprehensive near real-time maritime intelligence, within a predetermined area of interest, based at least partially on satellite imagery is provided herein. The method may include the following stages: applying operational analysis and a multi-sensor mission planning, to generate a coverage plan required for satellite coverage; receiving a plurality of acquired data from multiple sensors located on satellites and sensors located terrestrially, based on the coverage plan, wherein the acquired data is non-continuous over time; applying data verification, data extraction, data fusion and insight deduction on said received data, to produce near real-time data on specified maritime vessels, within said predetermined area of interest; producing a fused traffic analysis report comprising N fused, real world maritime images, such that the data verification, data extraction, data fusion and the insight deduction compensate for time gaps low image quality due to the non-continuous nature of the satellite imagery.
Windward | Date: 2014-07-31
Disclosed herein are formulations of imatinib or a phenylaminopyrimidine derivative compound for aerosolization and use of such formulations for inhaled aerosol administration of imatinib or a phenylaminopyrimidine derivative compound for the prevention or treatment of various fibrotic, carcinogenic, vascular and viral infectious diseases, including diseases associated with the lung, heart, kidney, liver, eye, central nervous system and surgical sites. In some embodiments, formulations and delivery options described herein allow for efficacious local delivery of imatinib or a phenylaminopyrimidine derivative compound or salt thereof. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures, indications and manufacturing processes for production and use of the compositions described. Also included are methods for identifying compounds and indications that may benefit by reformulation and inhalation administration.
News Article | January 9, 2014
In the summer of 2012, an oil tanker anchored mid-ocean transferred cargo for 19 hours. Separately, a ship en route to the Philippines turned its location-broadcasting system on and off, disappearing and reappearing every 36 hours. These anomalies of maritime behavior, which occur daily, would have probably gone undetected in the past. Today, advanced satellite imaging and communications technology, coupled with analytical software developed by an Israeli startup called Windward, identifies potential illegal activity in real time. Based in Tel Aviv, Windward was founded four years ago by two Israeli naval officers. Ami Daniel, the chief executive officer, served on a warship called the Hanit (meaning “spear”), which was blindsided by a Silkworm missile during the 2006 Lebanon War. The algorithms Windward developed were initially intended to tackle illegal fishing by analyzing and profiling normative patterns in sea traffic. The entrepreneurs discovered that their technology could also be used to monitor unusual behavior near, say, oil-drilling ports in Libya. "Everything affects everything else in the sea,” Daniel said in an interview. "We see when things are beginning to happen. We give you the insight first because we can see when patterns start changing.” To cash in on that ability, Windward has set its sights on the oil and gas industry. The startup’s investors estimate that the market could bring in hundreds of millions of dollars in revenue, on top of a comparable amount from homeland-security clients. Windward has about 10 customers that include law-enforcement agencies, navies and governments using the software to gather information and to detect smugglers. While Somali pirates have posed a threat to international shipping, the technology isn't designed to deal with piracy. Eden Shochat, a partner at Israeli venture-capital firm Aleph, which invested $5 million in Windward late last year, said the big-data startup is one of the country’s most promising new companies. "We absolutely see Windward as the next big company, like Waze,” Shochat said in an interview. Breaking into the oil and gas market is more difficult than other industries, but once a business has developed a solid reputation, clients tend to be quite loyal, Adi Karev, the global head of oil and gas at consulting firm Deloitte, said in an interview. "What makes this company unique is that its analytics can be used for a number of predictive and preventive decisions,” Karev said. "It will take time to ramp up, and it will require sensitivity and understanding."
News Article | March 23, 2015
Windward, a specialized data and analytics company focused on the maritime domain, has been named one of 10 Israeli startups to watch in 2015 in the Aerospace, Defense and Security sector by Frost & Sullivan. Windward's technology was recognized for bringing unprecedented visibility to the oceans by transforming maritime big data - the hundreds of millions of data points available daily on ships worldwide - into actionable intelligence that allows decision makers to identify suspicious ships before they reach their shores. Frost & Sullivan noted the growing stakes at sea for both governments and commercial entities as a significant catalyst for Windward's growth: "Frost & Sullivan forecasts show the maritime domain as a significant upcoming concern for countries and commercial maritime companies. The Windward solution is one of the only solutions to answer the market need for covering the 'wild west' of maritime activities." "We are delighted that Windward's technology has been recognized as a game changer in the maritime domain," said Ami Daniel, CEO and Co-Founder of Windward. "We are bringing visibility to a previously opaque world and generating insights that are relevant and actionable for stakeholders across industries." Originally developed for security applications and already in use by government and intelligence clients around the world, Windward's data platform is now being leveraged by financial institutions to identify new market trends and trading opportunities. "Ship activity across the oceans impacts nearly every industry, but the data available is largely unusable - it is massive, fragmented and unreliable, leaving decision makers across industries in the dark," continued Daniel. "Windward has created the world's first maritime data platform - the only place where all maritime data is aggregated and analyzed - giving our clients critical insights into the reality of what goes on at sea." Windward is a specialized data company, analyzing and organizing the world's maritime data. Ships transport over 90% of trade worldwide, but despite the massive stakes at sea, the data on ship activity is largely unusable: it is vast, fragmented and often intentionally manipulated. The oceans are the last analog market and the world's missing data link - and Windward is bridging that information gap. We have built the world's first maritime data platform, making the data accessible and actionable across verticals, from flagging criminal threats at sea to identifying new market trading opportunities. Our solution is in wide use among Intelligence and Governmental clients worldwide, and we are now bringing the same unprecedented visibility to additional markets. ForeSea, our new Finance solution, is giving traders, investors and analysts access to a gold mine of untapped market opportunities. For more information, go to http://www.windward.eu/
News Article | April 21, 2015
Windward, a maritime data and analytics company, was named a Red Herring Top 100 Europe company for 2015. This prestigious annual award recognizes innovative technologies making an impact across industries. "The recognition by Red Herring is a testament to the power of bringing data sciences to the maritime domain," said Ami Daniel, Windward's co-Founder and CEO. "Ship activity across the oceans impacts nearly every industry, but stakeholders have very limited visibility on what's happening at sea. We have built the world's first maritime data platform, the Windward Mind, which is making the data accessible and actionable, for the first time, for anyone with stakes at sea." Windward's technology is in wide use by Security, Intelligence and Law Enforcement agencies worldwide, who are using insights from Windward's data platform to identify suspicious ships before they reach their shores. Leveraging the same data platform, the only place in the world that aggregates, vets and analyzes all maritime data in real time, Windward is now providing financial markets with a completely new source of unmined data and insights, with huge value across asset classes. "Selecting startups that show the most potential for disruption and growth is never easy," said Alex Vieux, publisher and CEO of Red Herring. "We looked at hundreds and hundreds of candidates from all across the continent, and after much thought and debate, narrowed the list down to the Top 100 Winners. Each year, the competition gets tougher but we believe Windward demonstrates the vision, drive and innovation that define a Red Herring Top 100." Windward is a maritime data and analytics company, analyzing and organizing the world's maritime data. Ships transport over 90% of trade worldwide, but despite the massive stakes at sea, the data on ship activity is largely unusable: it is vast, fragmented and often intentionally manipulated. The oceans are the last analog market and the world's missing data link. Windward is bridging that information gap. We have built the Windward Mind, the world's first maritime data platform, making the data accessible and actionable across verticals, from flagging criminal threats at sea to identifying new market trading opportunities. Our solution is in wide use among Intelligence and Governmental clients worldwide, and we are now bringing the same unprecedented visibility to additional markets. FORESEA, our new Finance solution, is giving traders, investors and analysts access to a gold mine of untapped market opportunities. For more information, go to http://www.windward.eu/
News Article | April 27, 2015
Windward, which provides maritime data and analytics, has raised $10.8 million in funding led by Horizons Ventures, with participation from returning investor Aleph. This brings the company’s total raised so far to $15.8 million. The startup’s products currently include MARINT, which tracks vessel traffic using commercial satellites and alerts law enforcement and intelligence agencies about suspicious behavior, such as smuggling or illegal fishing. CEO and co-founder Ami Daniel tells TechCrunch that the funding will be used to build Windward’s data and analytics platform, scale up MARINT, and bring FORESEA, a financial platform targeted to commodity traders, hedge fund investors, and analysts that is currently in beta, to market. Daniel says Windward was founded to aggregate information about ship activity at sea, since “the data is massive, fragmented, and often intentionally manipulated.” “As the company evolved, we realized that the potential applications of real maritime visibility were far more wide-reaching than just security and intelligence, and that our data could bring huge value across the ecosystem, from financial markets to global supply chains, international trading patterns, and more,” he adds. For example, Windward’s data can be used to show how much oil is actually available in floating storages compared to how much has been reported, which is important for oil traders and anyone else who needs to keep an eye on oil prices. While there are other companies that analyze maritime data, Windward relies on big data to stand out. “While some companies look at aspects of what Windward is doing, no one is taking all maritime data, 24/7, analyzing it, vetting it, bringing cyber security algorithms to it, and making sense of it across verticals. What’s more, those providing maritime data today take an information services approach, a time intensive approach of people putting together reports, spreadsheets, etc.,” says Daniel. The company’s growth plans revolve around scaling up MARINT and FORESEA, as well as finding other applications for its data analysis platform through data partnership programs.