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Halas J.,Oddzial Onkologii Klinicznej Z Pododdzialem Dziennej Chemioterapii | Bryl M.,Oddzial Onkologii Klinicznej Z Pododdzialem Dziennej Chemioterapii | Spychalski L.,Oddzial Onkologii Klinicznej Z Pododdzialem Dziennej Chemioterapii | Szyszka-Barth K.,Oddzial Onkologii Klinicznej Z Pododdzialem Dziennej Chemioterapii | And 2 more authors.
Onkologia Polska | Year: 2010

Hyponatremia is the most frequently encountered electrolyte disturbance. Available therapy, i.e. saline, restriction of fluid intake, diuretics, is often ineffective with unpredictable results and potentially serious side effects. Dysregulation of vasopressin homeostasis are very important in pathogenesis hyponatremia. Non-peptide AVP receptor antagonists-vaptans are effective in the treatment of hyponatremia. Copyright © 2010 Cornetis. Source


Stangierski A.,Katedra i Klinika Endokrynologii | Czepczynski R.,Katedra i Klinika Endokrynologii | Ramlau R.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Sowinski J.,Katedra i Klinika Endokrynologii
Onkologia Polska | Year: 2010

Throughout the last years positron emission tomography (PET) with the use of 18-FDG has been increasingly applied in the diagnosis of neoplastic lung diseases and monitoring treatment progress. PET is highly efficient in diagnosing solitary pulmonary nodules, staging of non-small cell lung cancer and has a high prognostic value. During therapy, PET proves results very sensitive in the estimation of treatment response. After therapy, it helps to identify suspected recurrences. Opposite to conventional imaging studies, PET gives the possibility to visualize not only the morphology of the suspicious focus, but also its metabolism. That is why in a lot of circumstances PET with the use of 18-FDG is gaining importance compared to classically used CT. Other, less frequent applications of PET in pulmonary oncology is the identification of the primary focus in case of disseminated metastatic disease, as well as pleural mesothelioma. The value of this method is still questionable in patients with small cell lung cancer. The following article is an overview of applicability of PET with the use of 18-FDG. There is an emphasis on the benefits of PET in pulmonary oncology, but also on some clinical situations in which its value is limited. Copyright © 2010 Cornetis. Source


Donat P.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Ramlau R.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Nowak E.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Barinow-Wojewodzki A.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu
Kardiochirurgia i Torakochirurgia Polska | Year: 2010

Lung cancer is the most frequent malignant cancer in the world and it is characterized by the highest mortality rate. This type of cancer is the reason of about 20% of all deaths caused by cancerous diseases. On average, 28% of males and 10% of females die of lung cancer. The majority of ill people, who have undergone a diagnostic process, are considered to be at an advanced stage of this disease. Patients suffering from lung cancer have a relatively little chance of effective and permanent recovery. Prognosis of lung cancer remains disadvantageous. Early diagnosis has a decisive impact on the success in treatment. The risk of incidence is the highest among smokers, therefore,the role of primary prevention, i.e. breaking the habit, is crucial here. The cancer screening is oriented to detect earlier stages of advanced lung cancer. In the last couple of years, the modern diagnosticmethods have been developed including autofluorescence bronchoscopy. The following review shows case studies related to fluorescence of cells, the effects of autofluorescence bronchoscopy as well as possibilities of its usage in bronchology. Source


Donat P.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Ramlau R.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Spychalski L.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | Dyszkiewicz W.,Wielkopolskie Centrum Pulmonologii I Torakochirurgii W Poznaniu | And 2 more authors.
Onkologia Polska | Year: 2010

Introduction: The risk of development of the second primary malignant lung tumor in the patients operated because of non-small cell lung cancer (NSCLC) is estimated at 1 to 3 % in the first year after the operation. Autofluorescent bronchoscopy is a sensitive method for diagnosing preinvasive lesions and early forms of cancer in the bronchial tree in the postoperative period. Aim of the study: The identification of changes pertaining to intraepithelial carcinogenesis in the patients operated for of non-small cell lung cancer as a part of control check-ups, determining the significance of autofluorescent bronchoscopy in diagnosing preinvasive lesions and finding the correlation between a histological diagnosis of a primary tumor and a risk of development of preinvasive lesion. Material and methods: The analysis was conducted on 82 patients operated because of NSCLC and rescreened endoscopically. The biopsy specimens were drawn from abnormal and suspicious tissues under both white light and autofluorescent light. During rescreening, the Lam's nine-point histological classification system was used. Results: On average 21 months after the operation for NSCLC, 88 bronchoscopic examinations, both conventional and autofluorescent ones, were performed in 82 patients. The I or II degree of postoperative advancement was found in 62 patients out of the 82 analyzed. The lesions pertaining to intraepithelial neoplasia were diagnosed in six patients (7.3%). Five lesions were diagnosed solely by means of autofluorescent bronchoscopy while one lesion was visible in both autofluorescent bronchoscopy and the conventional one. Four patients were operated because of squamous cell carcinoma. Conclusions: The examinations of the patients after the operation for NSCLC by means of autofluorescent bronchoscopy enabled to diagnose preinvasive lesions in 6 patients, which constituted 7.3% of the analyzed. The patients, who were diagnosed with squamous cell carcinoma and underwent operation, are the group that benefits most from autofluorescent bronchoscopy. Copyright © 2010 Cornetis. Source

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