Wichita State University is a public research university in Wichita, Kansas, United States. It is the third largest university governed by the Kansas Board of Regents.Wichita State University offers more than 60 undergraduate degree programs in more than 200 areas of study in six colleges. The Graduate School offers 44 master's degrees in more than 100 areas and a specialist in education degree. It offers doctoral degrees in applied mathematics; audiology; chemistry; communicative disorders and science; nursing practice; physical therapy; psychology ; educational administration; aerospace, industrial and mechanical engineering; and electrical engineering and computer science.Wichita State University also hosts classes at four satellite locations. West Campus is located in Maize. This 9-acre campus hosts 100–150 university classes each academic semester. The university's South Campus began offering Wichita State University coursework at a new facility in Derby in January 2008. The WSU Downtown Center houses the university's Center for Community Support & Research and the Department of Physical Therapy. A quarter-mile northeast of campus, the Advanced Education in General Dentistry building, built in 2011, houses classrooms and a dental clinic. It is adjacent to the university's 75,000-square-foot Eugene M. Hughes Metropolitan Complex, where many of WSU noncredit courses are taught. Wikipedia.
Wimalasena K.,Wichita State University
Medicinal Research Reviews | Year: 2011
Vesicular monoamine transporters (VMAT) are responsible for the uptake of cytosolic monoamines into synaptic vesicles in monoaminergic neurons. Two closely related VMATs with distinct pharmacological properties and tissue distributions have been characterized. VMAT1 is preferentially expressed in neuroendocrine cells and VMAT2 is primarily expressed in the CNS. The neurotoxicity and addictive properties of various psychostimulants have been attributed, at least partly, to their interference with VMAT2 functions. The quantitative assessment of the VMAT2 density by PET scanning has been clinically useful for early diagnosis and monitoring of the progression of Parkinson's and Alzheimer's diseases and drug addiction. The classical VMAT2 inhibitor, tetrabenazine, has long been used for the treatment of chorea associated with Huntington's disease in the United Kingdom, Canada, and Australia, and recently approved in the United States. The VMAT2 imaging may also be useful for exploiting the onset of diabetes mellitus, as VMAT2 is also expressed in the β-cells of the pancreas. VMAT1 gene SLC18A1 is a locus with strong evidence of linkage with schizophrenia and, thus, the polymorphic forms of the VMAT1 gene may confer susceptibility to schizophrenia. This review summarizes the current understanding of the structure-function relationships of VMAT2, and the role of VMAT2 on addiction and psychostimulant-induced neurotoxicity, and the therapeutic and diagnostic applications of specific VMAT2 ligands. The evidence for the linkage of VMAT1 gene with schizophrenia and bipolar disorder I is also discussed. © 2010 Wiley Periodicals, Inc.
Overcash M.,Wichita State University
Anesthesia and Analgesia | Year: 2012
Contemporary comparisons of reusable and single-use perioperative textiles (surgical gowns and drapes) reflect major changes in the technologies to produce and reuse these products. Reusable and disposable gowns and drapes meet new standards for medical workers and patient protection, use synthetic lightweight fabrics, and are competitively priced. In multiple science-based life cycle environmental studies, reusable surgical gowns and drapes demonstrate substantial sustainability benefits over the same disposable product in natural resource energy (200%-300%), water (250%-330%), carbon footprint (200%-300%), volatile organics, solid wastes (750%), and instrument recovery. Because all other factors (cost, protection, and comfort) are reasonably similar, the environmental benefits of reusable surgical gowns and drapes to health care sustainability programs are important for this industry. Thus, it is no longer valid to indicate that reusables are better in some environmental impacts and disposables are better in other environmental impacts. It is also important to recognize that large-scale studies of comfort, protection, or economics have not been actively pursued in the last 5 to 10 years, and thus the factors to improve both reusables and disposable systems are difficult to assess. In addition, the comparison related to jobs is not well studied, but may further support reusables. In summary, currently available perioperative textiles are similar in comfort, safety, and cost, but reusable textiles offer substantial opportunities for nurses, physicians, and hospitals to reduce environmental footprints when selected over disposable alternatives. Evidenced-based comparison of environmental factors supports the conclusion that reusable gowns and drapes offer important sustainability improvements. The benefit of reusable systems may be similar for other reusables in anesthesia, such as laryngeal mask airways or suction canisters, but life cycle studies are needed to substantiate these benefits. Copyright © 2012 International Anesthesia Research Society.
Ma C.,Wichita State University
IEEE Transactions on Signal Processing | Year: 2011
This paper deals with vector (or multivariate) random fields in space and/or time with second-order moments, for which a framework is needed for specifying not only the properties of each component but also the possible cross relationships among the components. We derive basic properties of the covariance matrix function of the vector random field and propose three approaches to construct covariance matrix functions for Gaussian or non-Gaussian random fields. The first approach is to take derivatives of a univariate covariance function, the second one is to work on the univariate random field whose index domain is in a higher dimension and the third one is based on the scale mixture of separable spatio-temporal covariance matrix functions. To illustrate these methods, many parametric or semiparametric examples are formulated. © 2011 IEEE.
Bann J.G.,Wichita State University
Protein Science | Year: 2012
The protective antigen is a key component of the anthrax toxin, as it allows entry of the enzymatic components edema factor and lethal factor into the host cell, through the formation of a membrane spanning pore. This event is absolutely critical for the pathogenesis of anthrax, and although we have yet to understand the mechanism of pore formation, recent developments have provided key insights into how this process may occur. Based on the available data, a model is proposed for the kinetic steps for protective antigen conversion from prepore to pore. In this model, the driving force for pore formation is the formation of the phi (φ)-clamp, a region that forms a leak-free seal around the translocating polypeptide. Formation of the φ-clamp elicits movements within the prepore that provide steric freedom for the subsequent conformational changes required to form the membrane spanning pore. Published by Wiley-Blackwell. © 2011 The Protein Society.
Song Y.,Wichita State University
Proceedings - IEEE INFOCOM | Year: 2015
The size of a packet has a strong influence on the quality of wireless data communications. In traditional wireless networks, there is an inherent trade-off in determining the packet size. First of all, compared with long packets, short packets are less likely to be affected by the error-prone wireless channels. However, short packets suffer overhead due to headers. In mobile cognitive radio (CR) networks, determining the secondary user (SU) packet size becomes much more complicated and critical. In addition to all the impacts in traditional wireless networks, the primary user (PU) activity and the mobility of SUs and PUs have significant impacts on the SU packet size. Moreover, the channel fading caused by the SU mobility also has an impact on the SU packet size. More importantly, all these impacts on SU packet size constantly vary with time and space, which makes this issue extremely challenging. Without a careful design of the SU packet size, both SU and PU transmissions may suffer severe performance degradation. In this paper, the optimal SU packet size issue in mobile CR networks under fading channels is studied. We mathematically model these impacts and derive the optimal SU packet size. To the best of our knowledge, this is the first work that systematically investigates the optimal SU packet size issue in mobile CR networks. © 2015 IEEE.