Westminster College is a liberal arts college located in New Wilmington, Pennsylvania, United States. Founded in 1852, it is affiliated with the Presbyterian Church . The student population is approximately 1550 undergraduate and graduate students. Wikipedia.
Griffin III W.C.,Charleston Alcohol Research Center |
Griffin III W.C.,Medical University of South Carolina |
McGovern R.W.,Westminster College, Pennsylvania |
Bell G.H.,Medical University of South Carolina |
And 3 more authors.
Psychopharmacology | Year: 2013
Introduction: Prior research indicates methylphenidate (MPH) and alcohol (ethanol, EtOH) interact to significantly affect responses humans and mice. The present studies tested the hypothesis that MPH and EtOH interact to potentiate ethanol-related behaviors in mice. Methods: We used several behavioral tasks including: drug discrimination in MPH-trained and EtOH-trained mice, conditioned place preference (CPP), rota-rod and the parallel rod apparatus. We also used gas chromatographic methods to measure brain tissue levels of EtOH and the d- and l-isomers of MPH and the metabolite, ethylphenidate (EPH). Results: In discrimination, EtOH (1 g/kg) produced a significant leftward shift in the MPH generalization curve (1-2 mg/kg) for MPH-trained mice, but no effects of MPH (0.625-1.25 mg/kg) on EtOH discrimination in EtOH-trained mice (0-2.5 g/kg) were observed. In CPP, the MPH (1.25 mg/kg) and EtOH (1.75 g/kg) combination significantly increased time on the drug paired side compared to vehicle (30.7 %), but this was similar to MPH (28.8 %) and EtOH (33.6 %). Footslip errors measured in a parallel rod apparatus indicated that the drug combination was very ataxic, with footslips increasing 29.5 % compared to EtOH. Finally, brain EtOH concentrations were not altered by 1.75 g/kg EtOH combined with 1.25 mg/kg MPH. However, EtOH significantly increased d-MPH and l-EPH without changing l-MPH brain concentrations. Conclusions: The enhanced behavioral effects when EtOH is combined with MPH are likely due to the selective increase in brain d-MPH concentrations. These studies are consistent with observations in humans of increased interoceptive awareness of the drug combination and provide new clinical perspectives regarding enhanced ataxic effects of this drug combination. © 2012 Springer-Verlag.
Mellon S.N.,University of Rochester |
Mellon S.N.,Westminster College, Pennsylvania |
Mamajek E.E.,University of Rochester |
Mamajek E.E.,Jet Propulsion Laboratory |
And 2 more authors.
Astrophysical Journal | Year: 2017
We report the results of a study of archival SuperWASP light curves for stars in Scorpius-Centaurus (Sco-Cen), the nearest OB association. We use SuperWASP time-series photometry to extract rotation periods for 189 candidate members of the Sco-Cen complex and verify that 162 of those are members of the classic Sco-Cen subgroups of Upper Scorpius (US), Upper Centaurus-Lupus (UCL), and Lower Centaurus-Crux (LCC). This study provides the first measurements of rotation periods explicitly for large samples of pre-main-sequence (pre-MS) stars spanning the UCL and LCC subgroups. Our final sample of 157 well-characterized pre-MS stars spans ages of ∼10-20 Myr, spectral types of ∼F3-M0, and masses of M ≃ 0.3-1.5 . For this sample, we find a distribution of stellar rotation periods with a median of P rot ≃ 2.4 days, an overall range of 0.2 < P rot < 8 days, and a fairly well-defined mass-dependent upper envelope of rotation periods. This distribution of periods is consistent with recently developed stellar angular momentum evolution models. These data are significant because they represent an undersampled age range and the number of measurable rotation periods is large compared to recent studies of other regions. We also search for new examples of eclipsing disk or ring systems analogous to 1SWASP J140747.93-394542.6 (J1407), but find none. Our survey yielded five eclipsing binaries, but only one appears to be physically associated with the Sco-Cen complex. V2394 Oph is a heavily reddened (A V ≃ 5 mag) massive contact binary in the LDN 1689 cloud whose Gaia astrometry is clearly consistent with kinematic membership with the Ophiuchus star-forming region. © 2017. The American Astronomical Society. All rights reserved..
Hailey-Dunsheath S.,Cornell University |
Hailey-Dunsheath S.,Max Planck Institute for Extraterrestrial Physics |
Nikola T.,Cornell University |
Stacey G.J.,Cornell University |
And 8 more authors.
Astrophysical Journal Letters | Year: 2010
We report the detection of 158 μm [C II] fine-structure line emission from MIPS J142824.0+352619, a hyperluminous (L IR ∼ 10 13 L ⊙) starburst galaxy at z = 1.3. The line is bright, corresponding to a fraction L [C II]/L FIR 2 × 10-3 of the far-IR (FIR) continuum. The [C II], CO, and FIR continuum emission may be modeled as arising from photodissociation regions (PDRs) that have a characteristic gas density of n ∼ 104.2 cm-3, and that are illuminated by a far-UV radiation field ∼ 103.2 times more intense than the local interstellar radiation field. The mass in these PDRs accounts for approximately half of the molecular gas mass in this galaxy. The L [C II]/L FIR ratio is higher than observed in local ultraluminous infrared galaxies or in the few high-redshift QSOs detected in [C II], but the L [C II]/L FIR and L CO/L FIR ratios are similar to the values seen in nearby starburst galaxies. This suggests that MIPS J142824.0+352619 is a scaled-up version of a starburst nucleus, with the burst extended over several kiloparsecs. © 2010. The American Astronomical Society. All rights reserved..
Dickson P.E.,Hampshire College |
Arbour D.T.,University of Massachusetts Amherst |
Adrion W.R.,University of Massachusetts Amherst |
Gentzel A.,Westminster College, Pennsylvania
ITiCSE'10 - Proceedings of the 2010 ACM SIGCSE Annual Conference on Innovation and Technology in Computer Science Education | Year: 2010
Our research into automatic recording of the complete classroom experience has led to the development of many software systems, one of which captures an image stream of all content presented on a computer. We have just completed a first deployment of this computer capture system in which 3 separate courses were recorded for an entire semester with the content being presented to students within 24 hours of the class meeting time. This system has been envisioned as a component of a complete lecture capture system but a component with real value even when used as a stand alone. In this paper we discuss student feedback to this computer capture system, revision of system functionality, and thoughts on the usefulness of capturing computer content in computer science courses in general. Copyright 2010 ACM.
Strickland M.L.,Drexel University |
Boylan H.M.,Westminster College, Pennsylvania
Journal of Alternative and Complementary Medicine | Year: 2010
Objectives: The goal of this research is to design a novel model using protein folding to study Therapeutic Touch, a noncontact form of energy manipulation healing. Presented is a feasibility study suggesting that the denaturation path of ribonuclease A may be a useful model to study the energy exchange underlying therapeutic touch. Design: The folding of ribonuclease A serves as a controlled energy-requiring system in which energy manipulation can be measured by the degree of folding achieved. A kinetic assay and fluorescence spectroscopy are used to assess the enzyme-folding state. Results: The data suggest that the kinetic assay is a useful means of assessing the degree of refolding, and specifically, the enzyme function. However, fluorescence spectroscopy was not shown to be an effective measurement of enzyme structure for the purposes of this work. Conclusions: More research is needed to assess the underlying mechanism of therapeutic touch to complement the existing studies. An enzyme-folding model may provide a useful means of studying the energy exchange in therapeutic touch. © 2010, Mary Ann Liebert, Inc.
Kennedy S.A.,Westminster College, Pennsylvania
Journal of Chemical Education | Year: 2016
The green chemistry course taught at Westminster College (PA) incorporates nontraditional teaching techniques and texts to educate future chemists about the importance of using green chemistry principles. The course is designed to introduce green chemistry concepts and demonstrate their inherent necessity by discussing historical missteps by the chemical industry, and future design possibilities. Students learn to apply green chemistry principles through case studies and journal article activities, while connecting all of these resources and experiences with concept maps. The final course project requires students to create their own green chemistry educational materials. This nontraditional approach to teaching chemistry provides an opportunity for students to learn in dynamic ways and to be creative in their contributions to green chemistry. © 2015 The American Chemical Society and Division of Chemical Education, Inc.
Rennie B.,Westminster College, Pennsylvania
Journal for the Study of Religion, Nature and Culture | Year: 2015
Enough has been written on the cognitive and evolutionary bases of both art and religion to permit a theoretical understanding of these closely related behaviors. My argument is that religion and art are descendants of a common ancestral behavior that cannot be identified as either one or the other but has identifying features of both. It is my contention that such an understanding facilitates an improved comprehension of the history of religion as well as a coherent theoretical explanation of religious pluralism. As an example of the application and implication of this theory I will undertake a brief analysis of Biblical Prophecy as a complex of art forms bearing significant similarities to contemporary postcolonial literature and street theater. Both complexes communicate individual emotional responses to the environment that are transmitted and retained in the local culture and contribute to assured and persistent behavior. © Equinox Publishing Ltd 2015.
Cunningham C.N.,Westminster College, Pennsylvania |
Cunningham C.N.,University of Michigan |
Schmidt C.A.,Westminster College, Pennsylvania |
Schmidt C.A.,University of North Carolina at Chapel Hill |
And 4 more authors.
Experimental Cell Research | Year: 2014
TREX-2 is a five protein complex, conserved from yeast to humans, involved in linking mRNA transcription and export. The centrin 2 subunit of TREX-2 is also a component of the centrosome and is additionally involved in a distinctly different process of nuclear protein export. While centrin 2 is a known multifunctional protein, the roles of other human TREX-2 complex proteins other than mRNA export are not known. In this study, we found that human TREX-2 member PCID2 but not ENY2 is involved in some of the same cellular processes as those of centrin 2 apart from the classical TREX-2 function. PCID2 is present at the centrosome in a subset of HeLa cells and this localization is centrin 2 dependent. Furthermore, the presence of PCID2 at the centrosome is prevalent throughout the cell cycle as determined by co-staining with cyclins E, A and B. PCID2 but not ENY2 is also involved in protein export. Surprisingly, siRNA knockdown of PCID2 delayed the rate of nuclear protein export, a mechanism distinct from the effects of centrin 2, which when knocked down inhibits export. Finally we showed that co-depletion of centrin 2 and PCID2 leads to blocking rather than delaying nuclear protein export, indicating the dominance of the centrin 2 phenotype. Together these results represent the first discovery of specific novel functions for PCID2 other than mRNA export and suggest that components of the TREX-2 complex serve alternative shared roles in the regulation of nuclear transport and cell cycle progression. © 2013 Elsevier Inc.
Garrison J.C.,Westminster College, Pennsylvania
First Monday | Year: 2015
College students use Wikipedia frequently, despite educators' highly divided opinions about it, and so it is important to understand how and why they are using it. This study followed a first-year class of undergraduate, liberal arts students over the course of their first semester to see how they used, were influenced about, and rated Wikipedia. Data was collected via two surveys of the first-year class, as well as focus groups and a survey of college faculty. This study found that first-year students are uncertain about the variety of ways to use information sources like Wikipedia, and that a direct and balanced approach to this area from instructors may lead to better outcomes than strict prohibition or silence.
Resendes K.K.,Westminster College, Pennsylvania
Biochemistry and Molecular Biology Education | Year: 2015
Incorporating scientific literacy into inquiry driven research is one of the most effective mechanisms for developing an undergraduate student's strength in writing. Additionally, discovery-based laboratories help develop students who approach science as critical thinkers. Thus, a three-week laboratory module for an introductory cell and molecular biology course that couples inquiry-based experimental design with extensive scientific writing was designed at Westminster College to expose first year students to these concepts early in their undergraduate career. In the module students used scientific literature to design and then implement an experiment on the effect of cellular stress on protein expression in HeLa cells. In parallel the students developed a research paper in the style of the undergraduate journal BIOS to report their results. HeLa cells were used to integrate the research experience with the Westminster College "Next Chapter" first year program, in which the students explored the historical relevance of HeLa cells from a sociological perspective through reading The Immortal Life of Henrietta Lacks by Rebecca Skloot. In this report I detail the design, delivery, student learning outcomes, and assessment of this module, and while this exercise was designed for an introductory course at a small primarily undergraduate institution, suggestions for modifications at larger universities or for upper division courses are included. Finally, based on student outcomes suggestions are provided for improving the module to enhance the link between teaching students skills in experimental design and execution with developing student skills in information literacy and writing. © 2015 The International Union of Biochemistry and Molecular Biology.