Kalamazoo, MI, United States

Western Michigan University

www.wmich.edu
Kalamazoo, MI, United States

Western Michigan University is a public research university located in Kalamazoo, Michigan, United States. The university was established in 1903 by Dwight B. Waldo, and as of the Fall 2014 semester, its enrollment is 23,914.WMU has one of the largest aviation programs in the United States, and it is the site of the annual International Congress on Medieval Studies. The university's athletic teams compete in Division I of the National Collegiate Athletic Association and are collectively known as the Western Michigan Broncos. They compete in the Mid-American Conference for most sports. Wikipedia.


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A method of testing a computer program implementation according to a predefined design model, the program implementation having at least one method under test, employs a computer to generate a post-method corresponding to the method under test. A computer is further used to automatically generate a set of test cases. Then, using the automatically generated set of test cases, the computer explores different execution paths of the computer program implementation, by applying those test cases to both the method under test and the generated post-method, to reveal behavior that is not consistent with the behavior specified by the design model.


Patent
Western Michigan University | Date: 2016-10-28

A laser beam is transmitted through a drill bit comprising diamond or other suitable light-transmitting material having sufficient hardness. The laser beam exits a tip of the drill bit, thereby heating and softening the material being drilled at and/or near the interface of the drill with the material being drilled. The process may be utilized to drill hard and brittle materials such as ceramics and semiconductors, composites and ceramic matrix composites. The process may cause high pressure phase transformation, resulting in a more ductile and plastic material near the drill point/tip. The process provides more rapid drilling, improved surface quality in drilled holes, and less tool wear.


Patent
Western Michigan University | Date: 2016-11-23

A 3D metal printing machine or apparatus includes a welder that deposits one or more layers of metal, and a powered cutting tool that may be utilized to remove a portion of the metal deposited by the welder after the metal has solidified. Numerous layers of metal can be deposited and machined to form complex 3D metal parts. During fabrication, a part may be formed on a support whereby the part can be fabricated by welding and machining operations without removing the part from the support. A 3D CAD model of a part may be utilized to generate code that controls the 3D metal printing apparatus. A measuring device such as a probe or laser scanner may be utilized to measure the shape/size of parts in the 3D metal printing machine.


Patent
Western Michigan University | Date: 2017-01-17

A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a TNF binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (TK) by the virus. In another embodiment, the mutation arms the virus with a transgene to express a bacterial flagellin. The mutations can be present singly or in combination. Additional aspects include a method of treating cancerous cells with a composition as described herein, and a method of delivering at least one gene to cancerous cells in a subject.


Patent
Western Michigan University | Date: 2017-05-24

A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a TNF binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (TK) by the virus. In another embodiment, the mutation arms the virus with a transgene to express a bacterial flagellin. The mutations can be present singly or in combination. Additional aspects include a method of treating cancerous cells with a composition as described herein, and a method of delivering at least one gene to cancerous cells in a subject.


Patent
Western Michigan University | Date: 2015-07-31

A method of forming a self-supported electronic device, including depositing a sacrificial layer on a first surface substrate, wherein the sacrificial layer is substantially soluble in a first solvent. At least one device layer is deposited in a desired pattern on top of the sacrificial layer. The at least one device layer is substantially insoluble in the at least one device layer. The sacrificial layer is at least partially dissolved in the first solvent to release at least a portion of the first device layer from the substrate. The at least one device layer removed from the substrate forms a self-supported electronic device, which is a thin film electronic device having at least a portion thereof that is not supported by a material carrier.


Patent
Western Michigan University | Date: 2017-07-26

A method of forming a self-supported electronic device, including depositing a sacrificial layer on a first surface substrate, wherein the sacrificial layer is substantially soluble in a first solvent. At least one device layer is deposited in a desired pattern on top of the sacrificial layer. The at least one device layer is substantially insoluble in the at least one device layer. The sacrificial layer is at least partially dissolved in the first solvent to release at least a portion of the first device layer from the substrate. The at least one device layer removed from the substrate forms a self-supported electronic device, which is a thin film electronic device having at least a portion thereof that is not supported by a material carrier.


The 'anomeric effect' is the thermodynamic preference for polar substituents to occupy the axial position in the chair conformation of various heterocycles. The most common explanation given for this effect at present is hyperconjugation from the lone pairs on the ring heteroatom to the antibonding orbital between the anomeric carbon and its linking substituent. Alternatively, the anomeric effect could be explained by intramolecular electrostatic interactions between local dipoles. Few models can provide convincing data for either theory at the quantum-mechanical level. Now, using the extended block-localized wavefunction method, which is the simplest form of valence bond theory, we have evaluated the degree of hyperconjugation in various compounds that display the anomeric effect and have interpreted their conformational preferences in terms of steric, hyperconjugation and dispersion effects. The results provide strong evidence that hyperconjugative interactions are not responsible for the anomeric effect and that it is better interpreted in terms of electrostatic interactions. © 2010 Macmillan Publishers Limited. All rights reserved.


Lee H.,Western Michigan University
Applied Energy | Year: 2013

The optimum design of thermoelectric devices (thermoelectric generator and cooler) in connection with heat sinks was developed using dimensional analysis. New dimensionless groups were properly defined to represent important parameters of the thermoelectric devices. Particularly, use of the convection conductance of a fluid in the denominators of the dimensionless parameters was critically important, which leads to a new optimum design. This allows us to determine either the optimal number of thermocouples or the optimal thermal conductance (the geometric ratio of footprint of leg to leg length). It is stated from the present dimensional analysis that, if two fluid temperatures on the heat sinks are given, an optimum design always exists and can be found with the feasible mechanical constraints. The optimum design includes the optimum parameters such as efficiency, power, current, geometry or number of thermocouples, and thermal resistances of heat sinks. © 2013 Elsevier Ltd.


Grant
Agency: NSF | Branch: Standard Grant | Program: | Phase: ADVANCED TECH EDUCATION PROG | Award Amount: 1.60M | Year: 2016

The EvaluATE Center is an ATE Support Center dedicated to supporting and improving the evaluation practices of approximately 250 ATE grantees across the country. EvaluATE conducts webinars and workshops, blogs on evaluation practice, maintains a website with a digital resource library, develops materials to guide evaluation work, and conducts an annual survey of ATE grantees. EvaluATEs mission is to promote the goals of the ATE program by partnering with projects and centers to strengthen the programs evaluation knowledge base, expand the use of exemplary evaluation practices, and support the continuous improvement of technician education throughout the nation. EvaluATEs goals associated with this proposal are to: (1) Ensure that all ATE Principal Investigators and evaluators know the essential elements of a credible and useful evaluation; (2) Maintain a comprehensive collection of online resources for ATE evaluation; (3) Strengthen and expand the network of ATE evaluation stakeholders; and (4) Gather, synthesize, and disseminate data about the ATE program activities to advance knowledge about ATE/technician education. The Center plans to produce a comprehensive set of evaluation resources to complement other services, engaging several community college-based Principal Investigators, representatives from selected community colleges, and evaluators in that process.

EvaluATEs products are informed by current research on evaluation, the National Science Foundations priorities for the evaluation of ATE grants, and the needs of ATE PIs and evaluators for sound guidance that is immediately relevant and usable in their contexts. The fundamental nature of EvaluATEs work is geared toward supporting ATE grantees to use evaluation regularly to improve their work and demonstrate their impacts. All of EvaluATEs products are available to the public. EvaluATEs findings from the annual survey of ATE grantees aid in advancing understanding of the status of technician education and illuminate areas for additional research. Implementing a mixed methods research design the Center will investigate approaches and methods to assess the impact of activities associated with developing evaluation capacity building

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