Water Resources University is a university in Hanoi, Vietnam. The university was established in 1959 as the Electricity Water Resources Academy, spun off from the mother university Hanoi University of Technology. The university now has three campuses in Hanoi with a large campus in Ho Chi Minh City and a campus in Phan Rang-Tháp Chàm, Ninh Thuan Province. The university offers undergraduate and postgraduate programs in: water resources management, dam construction, irrigation, flood control, environmental management, civil construction, and hydroelectricity. Wikipedia.
Le D.-H.,Water Resources University |
Le L.,Vietnam National University, Hanoi
Current Pharmaceutical Design | Year: 2016
Background: Drug discovery is one important issue in medicine and pharmacology area. Traditional methods using target-based approach are usually time-consuming and ineffective. Recently, the problems are approached in a system-level view and therefore it is called systems pharmacology. This research field deals with the problems in drug discovery by integrating various kinds of biomedical and pharmacological data and using advanced computational methods. Ultimately, the problems are more effectively solved. One of the most important problem in systems pharmacology is prediction of drug-target interactions. Methods: In this review, we are going to summarize various computational methods for this problem. Results: More importantly, we formed a unified framework for the problem. In addition, to study human health and disease in a more systematically and effectively, we also presented an integrated scheme for a wider problem of prediction of disease-gene-drug associations. Conclusion: By presenting the unified framework and the integrated scheme, underlying computational methods for problems in systems pharmacology can be understood and complex relationships among diseases, genes and drugs can be identified effectively. © 2016 Bentham Science Publishers.
Hu Y.,Water Resources University |
Cheng H.,Peking University
Nature Communications | Year: 2017
China has invested heavily on alternative energy, but the effectiveness of such energy sources at substituting the dominant coal-fired generation remains unknown. Here we analyse the displacement of fossil-fuel-generated electricity by alternative energy, primarily hydropower, and by trans-provincial imported electricity in China between 1995 and 2014 using two-way fixed-effects panel regression models. Nationwide, each unit of alternative energy displaces nearly one-quarter of a unit of fossil-fuel-generated electricity, while each unit of imported electricity (regardless of the generation source) displaces ∼0.3 unit of fossil-fuel electricity generated locally. Results from the six regional grids indicate that significant displacement of fossil-fuel-generated electricity occurs once the share of alternative energy in the electricity supply mix exceeds ∼10%, which is accompanied by 10-50% rebound in the consumption of fossil-fuel-generated electricity. These findings indicate the need for a policy that integrates carbon taxation, alternative energy and energy efficiency to facilitate China's transition towards a low-carbon economy. © The Author(s) 2017.
Liu Q.-S.,Water Resources University
Desalination and Water Treatment | Year: 2017
To study the effects of activator on the surface and adsorptive properties of activated carbons (ACs), corncob-based ACs were prepared using H3PO4, KOH and K2CO3 as activators. Their surface physic-chemical characteristics were analyzed using SEM, FTIR, XPS, XRD and BET methods. Compared to other ACs, H3PO4 activated AC (AC-PA) had more oxygen-related groups, more hydrophilic surface and larger surface area (680.7 m2/g). Its pore size distribution was more heterogeneous. Resulted from the oxygen-containing and P-related groups, AC-PA gave favorable adsorption for Pb, with a maximum capacity of 298.5 mg/g. The adsorption of Pb onto other ACs was inferior and mainly through surface precipitation. Due to the combined effects of several interactions, the adsorption performance of ACs for phenol related to the concentration range. Surface properties including surface area, oxygen-containing groups and pore size distribution affected the interactions. AC-PA gave poor adsorption at low concentration but reached higher maximum uptake. Post-heat treatment of AC-PA strongly improved phenol adsorption especially at low concentration range. Accordingly, H3PO4 is more suitable to prepare ACs aiming at heavy metal removal. Other activators might be applicable when phenolic compounds are targeted. In addition, H3PO4 activation enjoyed the advantage of higher carbon yield. © 2017, Desalination Publications. All rights reserved.
Le D.-H.,University of Ulsan |
Le D.-H.,Water Resources University |
Kwon Y.-K.,University of Ulsan
Bioinformatics | Year: 2013
Motivation: Many studies have investigated the relationship between structural properties and dynamic behaviors in biological networks. In particular, feedback loop (FBL) and feedforward loop (FFL) structures have received a great deal of attention. One interesting and common property of FBL and FFL structures is their coherency of coupling. However, the role of coherent FFLs in relation to network robustness is not fully known, whereas that of coherent FBLs has been well established.Results: To establish that coherent FFLs are abundant in biological networks, we examined gene regulatory and signaling networks and found that FFLs are ubiquitous, and are in a coherently coupled form. This result was also observed in the species-based signaling networks that are integrated from KEGG database. By using a random Boolean network model, we demonstrated that these coherent FFLs can improve network robustness against update-rule perturbations. In particular, we found that coherent FFLs increase robustness because these structures induce downstream nodes to be robust against update-rule perturbations. Therefore, coherent FFLs can be considered as a design principle of human signaling networks that improve network robustness against update-rule perturbations. © 2013 The Author Published by Oxford University Press. All rights reserved.
Cardenas M.B.,University of Texas at Austin |
Jiang X.-W.,Water Resources University
Water Resources Research | Year: 2010
In this paper, we investigate the effects of systematic and local heterogeneity on groundwater flow, transport, and residence time distributions (RTDs) of basins where groundwater flow is topography driven. Systematic heterogeneity is represented by an exponentially depth-decreasing hydraulic conductivity and porosity, and local heterogeneity is represented by the dispersivity. The RTDs for both a simple basin with one flow system and a basin with nested local and regional systems gradually evolve to a power law RTD with more pronounced systematic heterogeneity. Exponential decrease of poromechanical properties enhances shallow circulation and subdues deep and regional flows leading to longer flushing times for the large part of the domain, while the shallower portions flush solutes rapidly. Therefore, deeper basins lead to more persistent and pronounced power law RTDs when the poromechanical properties systematically decrease with depth. Separate contributions to the RTD due to stagnation zones associated with local flow cells and due to deeper immobile zones were identified; each leads to a different tailing behavior. Local heterogeneity slightly enhances the power law RTD by causing the tailing to begin earlier but does not affect the late time portion of the RTD. Systematic depth-dependent heterogeneity is an important factor controlling the circulation and associated RTDs of subsurface fluids. It contributes significantly to generation of power law RTDs. © 2010 by the American Geophysical Union.
Li H.,Temple University |
Boufadel M.C.,Water Resources University
Nature Geoscience | Year: 2010
Oil spilled from the tanker Exxon Valdez in 1989 (refs1, 2) persists in the subsurface of gravel beaches in Prince William Sound, Alaska. The contamination includes considerable amounts of chemicals that are harmful to the local fauna3. However, remediation of the beaches was stopped in 1992, because it was assumed that the disappearance rate of oil was large enough to ensure a complete removal of oil within a few years. Here we present field data and numerical simulations of a two-layered beach with a small freshwater recharge in the contaminated area, where a high-permeability upper layer is underlain by a low-permeability lower layer. We find that the upper layer temporarily stored the oil, while it slowly and continuously filled the lower layer wherever the water table dropped below the interface of the two layers, as a result of low freshwater recharge from the land. Once the oil entered the lower layer, it became entrapped by capillary forces and persisted there in nearly anoxic conditions that are a result of the tidal hydraulics in the two-layered beaches. We suggest that similar dynamics could operate on tidal gravel beaches around the world, which are particularly common in mid- and high-latitude regions4,5, with implications for locating spilled oil and for its biological remediation. © 2010 Macmillan Publishers Limited. All rights reserved.
Szilagyi J.,Water Resources University
Water Resources Research | Year: 2015
Thirty year normal (1981-2010) monthly latent heat fluxes (ET) over the conterminous United States were estimated by a modified Advection-Aridity model from North American Regional Reanalysis (NARR) radiation and wind as well as Parameter-Elevation Regressions on Independent Slopes Model (PRISM) air and dew-point temperature data. Mean annual ET values were calibrated with PRISM precipitation (P) and validated against United States Geological Survey runoff (Q) data. At the six-digit Hydrologic Unit Code level (sample size of 334) the estimated 30 year normal runoff (P - ET) had a bias of 18 mm yr-1, a root-mean-square error of 96 mm yr-1, and a linear correlation coefficient value of 0.95, making the estimates on par with the latest Land Surface Model results but without the need for soil and vegetation information or any soil moisture budgeting. © 2015. American Geophysical Union.
Rivera D.,Water Resources University
Journal of Hydrology | Year: 2014
Since the recent High Level Meeting on National Drought Policy held in Geneva in 2013, a greater concern about the creation and adaptation of national drought monitoring systems is expected. Consequently, backed by international recommendations, the use of Standardized Drought Indices (SDI), such as the Standardized Precipitation Index (SPI), as an operational basis of drought monitoring systems has been increasing in many parts of the world. Recommendations for the use of the SPI, and consequently, those indices that share its properties, do not take into account the limitations that this type of index can exhibit under the influence of multidecadal climate variability. These limitations are fundamentally related to the lack of consistency among the operational definition expressed by this type of index, the conceptual definition with which it is associated and the political definition it supports. Furthermore, the limitations found are not overcome by the recommendations for their application. This conclusion is supported by the long-term study of the Standardized Streamflow Index (SSI) in the arid north-central region of Chile, under the influence of multidecadal climate variability. The implications of the findings of the study are discussed with regard to their link to aspects of drought policy in the cases of Australia, the United States and Chile. © 2014 Elsevier B.V.
Tuan T.Q.,Water Resources University
Coastal Engineering Journal | Year: 2013
Extensive laboratory experiments were carried out to investigate the efficiency of low (vertical) crown-walls on the reduction of wave overtopping on sea-dikes. It is shown that the reduction of wave overtopping discharge by crown-walls is inadequately described in the TAW-2002 guidelines. A new approach for the wall influence has therefore been developed, explicitly taking into account both the wall height and the promenade width. The approach can straightforwardly be incorporated in the original formulations of TAW-2002 to significantly improve the prediction of wave overtopping on sea-dikes crowned with this type of walls. © 2013 World Scientific Publishing Company and Japan Society of Civil Engineers.
Ardhuin F.,French Research Institute for Exploitation of the Sea |
Roland A.,Water Resources University
Journal of Geophysical Research: Oceans | Year: 2012
Coastal reflection is introduced in a phase-averaged numerical wave model, first with a constant coefficient, and then with a reflection coefficient defined from the shoreface slope and that depends on the incident wave height and mean frequency. This parameterization is used in both regular and unstructured grids. The calibration involves a site-specific shoreface slope that is associated with the local geomorphology of the shoreline. Using wave buoy data off Hawaii and the U.S. West Coast, it is found that coastal reflection is necessary to reproduce observed directional properties of coastal sea states. Errors on the mean directional spread are reduced by up to 30% for the frequency band 0.04 to 0.30 Hz with, at most locations, very little impact on the mean direction and energy levels. The most accurate results are obtained using the parameterization based on the shoreface slope, provided that this slope is estimated accurately. These parameterizations are validated using seismic noise data. Using data from the U.S. West Coast it is shown that the reflection defined from the shoreface slope can improve the correlation between measured and modeled seismic noise. © 2012 American Geophysical Union. All Rights Reserved.