Wageningen University and Research Centre is a Dutch public university in Wageningen, Netherlands. It consists of Wageningen University and the former agricultural research institutes ) of the Dutch Ministry of Agriculture. Wageningen UR trains specialists in life science and focuses its research on scientific, social and commercial problems in the field of life science and natural resources. In the field of agricultural science, the university is considered world-class. Wikipedia.
Academisch Medisch Centrum and Wageningen University | Date: 2017-07-05
The invention therefore provides a compound effective against Ralstonia pickettii for use in the treatment or prevention of insulin resistance, obesity or type II diabetes of a subject. Preferably, said compound is selected from the group consisting of an antibiotic effective against Ralstonia pickettii, an immunogenic compound capable of producing a protective immune response in a subject, and an antibody which specifically binds to Ralstonia pickettii or a binding fragment thereof. The invention further provides an in vitro method of diagnosis or prediction of insulin resistance, obesity or type II diabetes in a subject, comprising determining the presence of Ralstonia pickettii or the presence of an antibody which specifically binds to Ralstonia pickettii in a test sample of said subject. In another aspect, the invention provides the use of an antibody binding specifically to an antigen of Ralstonia pickettii, a Ralstonia pickettii cell, and/or a nucleic acid hybridizing under stringent conditions to a nucleic acid from Ralstonia pickettii in a method according to the invention. The invention further provides the use of a kit comprising said antibody, a nucleic acid as defined in above, and optionally comprising a Ralstonia pickettii bacteria or a nucleic acid or protein thereof, a further reagent or a conventional kit component.
Wageningen University | Date: 2017-07-26
The invention relates to a new gene that produces a protein which is capable of inferring oomycete resistance, more preferably resistance to Phytophthora infestans when expressed in a plant, wherein said nucleotide sequence encodes a protein that is encoded by the protein produced by the nucleotide sequence of Fig.10 or the protein depicted in Fig. 11 or a nucleotide sequence that codes for a protein that has an identity of at least 95% with said protein produced by the nucleotide sequence of Fig. 10 or the protein depicted in Fig. 11. The invention also relates to a method for providing at least partial resistance or increasing resistance in a plant against an oomycete infection comprising providing a plant or a part thereof with a nucleotide sequence as indicated above or a functional fragment thereof, preferably wherein said plant is a plant from the Solanaceae family, more preferably Solanum tuberosum.
Wageningen University | Date: 2016-10-14
The invention relates to a resistance gene and functional homologues or fragments thereof isolated from S. chacoense, S. berthaultii, S. sucrense or S. tarijense. Moreover, the invention relates to the use of said resistance gene, for example the use of said resistance gene in a method to increase or confer at least partial resistance in a plant to an oomycete infection. The invention provides an isolated or recombinant nucleic acid sequence comprising a nucleic acid sequence encoding one of the amino acid sequences of FIG. 4 or a functional fragment or a functional homologue thereof such as those presented in FIG. 13.
The United States Of America and Wageningen University | Date: 2016-12-22
The present invention relates to formulations of volatile organic compounds having effects on Otiorhynchus weevils e.g., Otiorhynchus sulcatus. In some embodiments, volatile organic compounds selected from (E)-2-hexenol, (Z)-2-pentenol, methyl eugenol and a combination thereof are effective for attracting Otiorhynchus weevils. The invention also relates to traps and particularly to a weevil trap combined with any one or more of the disclosed volatile organic compounds selected from (E)-2-hexenol, (Z)-2-pentenol, methyl eugenol, and light which are effective for monitoring and controlling Otiorhynchus weevils.
Wageningen University | Date: 2015-07-06
A first aspect of the present invention relates to a process for recovering crystalline elemental selenium (Se) from an aqueous composition, such as waste water or groundwater. A second aspect of the present invention further relates to a microbial sludge comprising crystalline elemental selenium, which sludge may be used in the further recovery of elemental selenium.
Wageningen University | Date: 2017-04-05
The present invention relates to a screening method for the identification of non-genetically modified plants with a specific resistance response to a pathogen, the method involving the transgenic expression of a putative R gene construct, the identification of polymorphic markers in the putative R gene by comparing its sequence with known R gene sequences, and screening of non-genetically modified plant populations for the presence of these polymorphic markers.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 34.71M | Year: 2017
The IoF2020 project is dedicated to accelerate adoption of IoT for securing sufficient, safe and healthy food and to strengthen competitiveness of farming and food chains in Europe. It will consolidate Europes leading position in the global IoT industry by fostering a symbiotic ecosystem of farmers, food industry, technology providers and research institutes. The IoF2020 consortium of 73 partners, led by Wageningen UR and other core partners of previous key projects such as FIWARE and IoT-A, will leverage the ecosystem and architecture that was established in those projects. The heart of the project is formed by 19 use cases grouped in 5 trials with end users from the Arable, Dairy, Fruits, Vegetables and Meat verticals and IoT integrators that will demonstrate the business case of innovative IoT solutions for a large number of application areas. A lean multi-actor approach focusing on user acceptability, stakeholder engagement and sustainable business models will boost technology and market readiness levels and bring end user adoption to the next stage. This development will be enhanced by an open IoT architecture and infrastructure of reusable components based on existing standards and a security and privacy framework. Anticipating vast technological developments and emerging challenges for farming and food, the 4-year project stays agile through dynamic budgeting and adaptive decision-making by an implementation board of representatives from key user organizations. A 6 M mid-term open call will allow for testing intermediate results and extending the project with technical solutions and test sites. A coherent dissemination strategy for use case products and project learnings supported by leading user organizations will ensure a high market visibility and an increased learning curve. Thus IoF2020 will pave the way for data-driven farming, autonomous operations, virtual food chains and personalized nutrition for European citizens.
De Visser J.A.G.M.,Wageningen University |
Krug J.,University of Cologne
Nature Reviews Genetics | Year: 2014
The genotype-fitness map (that is, the fitness landscape) is a key determinant of evolution, yet it has mostly been used as a superficial metaphor because we know little about its structure. This is now changing, as real fitness landscapes are being analysed by constructing genotypes with all possible combinations of small sets of mutations observed in phylogenies or in evolution experiments. In turn, these first glimpses of empirical fitness landscapes inspire theoretical analyses of the predictability of evolution. Here, we review these recent empirical and theoretical developments, identify methodological issues and organizing principles, and discuss possibilities to develop more realistic fitness landscape models. © 2014 Macmillan Publishers Limited. All rights reserved.
Sagis L.M.C.,Wageningen University
Reviews of Modern Physics | Year: 2011
The dynamic properties of interfaces often play a crucial role in the macroscopic dynamics of multiphase soft condensed matter systems. These properties affect the dynamics of emulsions, of dispersions of vesicles, of biological fluids, of coatings, of free surface flows, of immiscible polymer blends, and of many other complex systems. The study of interfacial dynamic properties, surface rheology, is therefore a relevant discipline for many branches of physics, chemistry, engineering, and life sciences. In the past three to four decades a vast amount of literature has been produced dealing with the rheological properties of interfaces stabilized by low molecular weight surfactants, proteins, (bio)polymers, lipids, colloidal particles, and various mixtures of these surface active components. In this paper recent experiments are reviewed in the field of surface rheology, with particular emphasis on the models used to analyze surface rheological data. Most of the models currently used are straightforward generalizations of models developed for the analysis of rheological data of bulk phases. In general the limits on the validity of these generalizations are not discussed. Not much use is being made of recent advances in nonequilibrium thermodynamic formalisms for multiphase systems, to construct admissible models for the stress-deformation behavior of interfaces. These formalisms are ideally suited to construct thermodynamically admissible constitutive equations for rheological behavior that include the often relevant couplings to other fluxes in the interface (heat and mass), and couplings to the transfer of mass from the bulk phase to the interface. In this review recent advances in the application of classical irreversible thermodynamics, extended irreversible thermodynamics, rational thermodynamics, extended rational thermodynamics, and the general equation for the nonequilibrium reversible-irreversible coupling formalism to multiphase systems are also discussed, and shown how these formalisms can be used to generate a wide range of thermodynamically admissible constitutive models for the surface stress tensor. Some of the generalizations currently in use are shown to have only limited validity. The aim of this review is to stimulate new developments in the fields of experimental surface rheology and constitutive modeling of multiphase systems using nonequilibrium thermodynamic formalisms and to promote a closer integration of these disciplines. © 2011 American Physical Society.
Van Huis A.,Wageningen University
Annual Review of Entomology | Year: 2013
With a growing world population and increasingly demanding consumers, the production of sufficient protein from livestock, poultry, and fish represents a serious challenge for the future. Approximately 1,900 insect species are eaten worldwide, mainly in developing countries. They constitute quality food and feed, have high feed conversion ratios, and emit low levels of greenhouse gases. Some insect species can be grown on organic side streams, reducing environmental contamination and transforming waste into high-protein feed that can replace increasingly more expensive compound feed ingredients, such as fish meal. This requires the development of cost-effective, automated mass-rearing facilities that provide a reliable, stable, and safe product. In the tropics, sustainable harvesting needs to be assured and rearing practices promoted, and in general, the food resource needs to be revalorized. In the Western world, consumer acceptability will relate to pricing, perceived environmental benefits, and the development of tasty insect-derived protein products. © 2013 by Annual Reviews. All rights reserved.