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Rāmachandrapuram, India

Mrutyunjaya R.R.,Vsm College | Venkateswarlu Y.,Vsm College
Research Journal of Chemistry and Environment | Year: 2011

Air-dried, milled roots of Piper qfficinrum (500gm) were extracted repeatedly with dichloro-methane. After removal of solvent in vacuo, the CH 2Cl 2-solvent residue was fractionated by using hexane and ethyl acetate solvents. After fractionation, all fractions are submitted for NMR spectroscopy. Out of all fractions interesting fractions are subjected to column chromatography, so that three pure compounds as piplartine, piperine and sesamin were isolated. All are known compounds as they are characterized by using reference data. Piplartine and piperine are alkaloids and sesamin is a lignin compound. Structures of the isolated compounds have been assigned on the basis of their analytical data. By surveying the literature compound sesamin is a lignin first to be isolated from piper family. Source

Rao R.M.,Vsm College | Saranapu N.,Vsm College | Ramanujan V.B.,Vsm College | Sastry C.P.S.,Vsm College | And 2 more authors.
Asian Journal of Chemistry | Year: 2011

Antimicrobial activities of various solvent extracts of Piper officinarum were determined against a wide variety of pathogenic bacteria. Crude extracts of Piper officinarum shows mild to moderate activities for most of the treated bacteria. Ethyl acetate extract, chloroform extracts and methanol extracts showed antibacterial effect against most of the tested organisms. It has been expected that the present work on antimicrobial screening of the plant materials will help researchers who wish to work in designing clinical drugs concerning the killer diseases. Source

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