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Vladivostok, Russia

Pacific State Medical University , formerly known as VSMU is a university in Vladivostok in the Far East of Russia.At the beginning, since 1956 VSMU was the Medical Faculty of the Far Eastern State University, but in 2 years it became Vladivostok State Medical Institute . Institute was reorganized into the University in 1995, in 2013 the University was renamed and reorganized into Pacific State Medical University.Faculties of the Pasific State Medical University: The Medical Faculty The Military Faculty The Military Training Center The Pediatric Faculty The Faculty of Medical Prophylactic and Medical BiochemistryAmong the medical Universities of the Far East PSMU - the only institution that trains doctors at Faculty Medical Prophylactic , providing preventive measures for healthy living of the population of Khabarovsk, Primorsky and Kamchatka Territories, Amur, Sakhalin and Magadan regions, the Republic of Sakha and Chukotka. The Pharmaceutical Faculty The Stomatological Faculty The Higher Nursing Education and Social Work Faculty The Clinical Psychology Faculty The Continuous Medical Education The Postgraduate and Further Degree Studies Pre-University Training Wikipedia.

Agafonova I.G.,RAS Pacific Institute of Bioorganic Chemistry | Kotel'nikov V.N.,Vladivostok State Medical University | Eichhoff U.,Bruker Biospin Gmbh
Applied Magnetic Resonance

OXYS rats represent a selection strain of laboratory animals, which are characterized by the accelerated senescence. Substantial morphologic changes of cerebral vessels were revealed in the senescence-accelerated OXYS rats by the noninvasive MRI diagnostics using the induced arterial hypertension and the author's original methods. These changes appeared as vascular lesions with a thickening of the intimae and the increasing of the signal intensity from blood in cerebral vessels. Cerebral arterial hypertension in normotensive Wistar rats developed as result of intraperitoneal injections of hydrocortisone acetate and diet enriched by sodium ions. The pathology of cerebral vessels in OXYS rats began its development much earlier and was based on spontaneous hypertension in connection with initially elevated blood pressure as well as the genotype of the animals. Four different inductors (two vasodilators and two vasoconstrictors) were used in the study of the endothelium-independent and endothelium-dependent vasodilatation and vasoconstrictions. We have compared previously unknown effects of these inductors on cerebral vessels in senescence-accelerated OXYS rats and those in normal Wistar rats. The response of the arteries to the action of inductors showed changes in the status of anterior, middle, and posterior cerebral arteries of circle Willis. Thus, we have indicated the changes in compensatory and adaptive characters of arteries in hypertensive OXYS rats in comparison with hypertensive Wistar rats. Reduced vasodilator response in the middle cerebral arteries suggests an elevated risk for development of arterial hypertension in these rats. © 2014 Springer-Verlag Wien. Source

Kotsiuba A.Y.,Vladivostok State Medical University
Morfologii{combining double inverted breve}a (Saint Petersburg, Russia)

Immunocytochemical method was used to determine the distribution of neurons expressing heme oxygenase-2 (HO-2-positive neurons) in the nuclei of various parts of the brainstem of 16 male Wistar rats. The sizes of neurons and the optical density of the product of histochemical reaction in their cytoplasm were determined in the nuclei studied. HO-2-positive neurons, differing in shape, size and numbers, were identified in the nuclei of the medulla oblongata, pons and midbrain. HO-2-positive cells were found 3-5 times more frequently in the sensory nuclei as compared to the motor ones. At the same time, relatively large number of nuclei was detected, which contained either no or a few HO-2-positive neurons. Source

A hygienic estimation of the actual average daily dose (AADD) of iron, consumed by the adolescent population with the sources of its per oral administration in human bodies in the conditions of iron excess (0.8 mg/l) in tap water has been performed. An object of the study was a random sample of 156 schoolchildren aged 14-17 years from Vladivostok. Methods: All adolescents were interviewed with use of a questionnaire that included questions about daily consumption of tap water, bottled water, 21 food products and dishes. Iron concentration in food and drinking water was determined according to the reference tables and laboratory findings. Results: The harmless levels of AADD of iron for adolescent health (about 17 mg/day) were stated. An occurrence frequency of iron consumption deficiency was equal to 28.08 (boys) and 58,54 (girls) cases per 100 adolescents. Conclusions: Against iron excess in tap water according to the organoleptic limiting sign of iron content harmfulness (up to 2.7 MPC), iron consumption deficiency is formed by lower intake of high bioavailable iron sources: eggs, fishes (girls), eggs, sausage products and animal meat (boys). © Northern State Medical University, Arkhangelsk. Source

Van Loghem J.,Doctors Company | Yutskovskaya Y.A.,Vladivostok State Medical University | Werschler W.M.P.,University of Washington
Journal of Clinical and Aesthetic Dermatology

Background: Calcium hydroxylapatite is one of the most well-studied dermal fillers worldwide and has been extensively used for the correction of moderate-to-severe facial lines and folds and to replenish lost volume. Objectives: To mark the milestone of 10 years of use in the aesthetic field, this review will consider the evolution of calcium hydroxylapatite in aesthetic medicine, provide a detailed injection protocol for a global facial approach, and examine how the unique properties of calcium hydroxylapatite provide it with an important place in today's market. Methods: This article is an up-to-date review of calcium hydroxylapatite in aesthetic medicine along with procedures for its use, including a detailed injection protocol for a global facial approach by three expert injectors. Conclusion: Calcium hydroxylapatite is a very effective agent for many areas of facial soft tissue augmentation and is associated with a high and well-established safety profile. Calcium hydroxylapatite combines high elasticity and viscosity with an ability to induce long-term collagen formation making it an ideal agent for a global facial approach. Source

Dreno B.,University of Nantes | Layton A.,Harrogate and District NHS Foundation Trust | Zouboulis C.C.,Dessau Medical Center | Lopez-Estebaranz J.L.,Hospital Universitario Fundacion Alcorcon | And 5 more authors.
Journal of the European Academy of Dermatology and Venereology

In the adult female, acne is a chronic condition with a substantial negative psychological, social and emotional impact. Based on time of onset, two subtypes of adult female acne are recognized: 'persistent acne' is a continuation of the disease from adolescence, while 'late-onset acne' first presents in adulthood. The morphological characteristics of adult female acne are often distinct from adolescent acne. In adults, inflammatory lesions (particularly papules, pustules and nodules) are generally more prominent on the lower chin, jawline and neck, and comedones are more often closed comedones (micro cysts). Adult acne is mainly mild-to-moderate in severity and may be refractory to treatment. A holistic approach to acne therapy should be taken in adult females, which combines standard treatments with adjunctive therapy and cosmetic use. A number of factors specific to the adult female influence choice of treatment, including the predisposition of older skin to irritation, a possible slow response to treatment, a high likelihood of good adherence, whether of child-bearing age, and the psychosocial impact of the disease. Adherence to therapy should be encouraged through further patient education and a simplified regimen that is tailored to suit the individual patient's needs and lifestyle. This article reviews the specific characteristics of adult female acne, and provides recommendations for acne therapy in this patient group. © 2013 European Academy of Dermatology and Venereology. Source

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