Entity

Time filter

Source Type

Pine Bluff, AR, United States

Buzatu D.A.,U.S. Food and Drug Administration | Moskal T.J.,Vivione Biosciences | Williams A.J.,U.S. Food and Drug Administration | Cooper W.M.,U.S. Food and Drug Administration | And 2 more authors.
PLoS ONE | Year: 2014

Foodborne illnesses occur in both industrialized and developing countries, and may be increasing due to rapidly evolving food production practices. Yet some primary tools used to assess food safety are decades, if not centuries, old. To improve the time to result for food safety assessment a sensitive flow cytometer based system to detect microbial contamination was developed. By eliminating background fluorescence and improving signal to noise the assays accurately measure bacterial load or specifically identify pathogens. These assays provide results in minutes or, if sensitivity to one cell in a complex matrix is required, after several hours enrichment. Conventional assessments of food safety require 48 to 56 hours. The assays described within are linear over 5 orders of magnitude with results identical to culture plates, and report live and dead microorganisms. This system offers a powerful approach to real-time assessment of food safety, useful for industry self-monitoring and regulatory inspection. Source


Patent
Vivione Biosciences | Date: 2014-03-26

In various embodiments, the present disclosure describes methods and systems for detecting microbes in a sample. The methods are generally applicable to quantifying the number of target bacteria in a sample counted from a detection region of a flow cytometer histogram. The detection methods can be employed in the presence of other microorganisms and other non-target microbe components to selectively quantify the amount of a target microbe. The methods are advantageous over those presently existing for testing of foodstuffs and diagnostic evaluation in their speed, accuracy and ease of use. Various swab collection devices and kits useful for practicing the present disclosure are also described herein.


Patent
Vivione Biosciences | Date: 2014-03-26

In various embodiments, the present disclosure describes methods and systems for detecting microbes in a sample. The methods are generally applicable to quantifying the number of target bacteria in a sample counted from a detection region of a flow cytometer histogram. The detection methods can be employed in the presence of other microorganisms and other non-target microbe components to selectively quantify the amount of a target microbe. The methods are advantageous over those presently existing for testing of foodstuffs and diagnostic evaluation in their speed, accuracy and ease of use. Various swab collection devices and kits useful for practicing the present disclosure are also described herein.


Trademark
Vivione Biosciences | Date: 2013-07-11

Systems for detecting and analyzing microbes comprising computer software, computer hardware, lasers, photo-multipliers and molecular laboratory devices. Laboratory analysis in the field of the detection and analysis of microbes.


Trademark
Vivione Biosciences | Date: 2013-07-11

in silico based methods for designing novel compounds.

Discover hidden collaborations