Virginia Polytechnic Institute and State University

www.vt.edu
Blacksburg, VA, United States

Virginia Polytechnic Institute and State University, popularly known as Virginia Tech, is a public land-grant university with a main campus in Blacksburg, Virginia, educational facilities in six regions statewide, and a study-abroad site in Switzerland. The commonwealth's third-largest university and a leading research institution, Virginia Tech offers 225 undergraduate and graduate degree programs to some 31,000 students and manages a research portfolio of $454 million. The university fulfills its land-grant mission of transforming knowledge to practice through technological leadership and by fueling economic growth and job creation locally, regionally, and across Virginia.The Virginia Tech Board of Visitors serves as the university's governing body. The board comprises 13 members who are appointed by the governor of Virginia. Serving as ex-officio, non-voting representatives are the president of the state Board of Agriculture and Consumer Services; the presidents of the university's faculty senate and staff senate; and an undergraduate student and a graduate student selected through a competitive review process. Wikipedia.


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Patent
The University Of Texas System, Virginia Polytechnic Institute and State University | Date: 2016-09-19

Disclosed are polybenzimidazoles containing sulfonyl groups. The polymers can be synthesized in Eatons reagent from 3,3,4,4-tetraaminodiphenylsulfone, which itself can be synthesized from 4,4-dichlorodiphenylsulfone. Methods of synthesizing the polymers are disclosed. The disclosed polymers can be used for high temperature H_(2)/CO_(2 )separation membranes and other uses.


Patent
Virginia Polytechnic Institute and State University | Date: 2016-10-14

A process for cleaning and dewatering hydrophobic particulate materials is presented. The process is performed in in two steps: 1) agglomeration of the hydrophobic particles in a first hydrophobic liquid/aqueous mixture; followed by 2) dispersion of the agglomerates in a second hydrophobic liquid to release the water trapped within the agglomerates along with the entrained hydrophilic particles.


Patent
Virginia Polytechnic Institute and State University | Date: 2016-10-18

Aspects of non-linear droop control are described herein. In one embodiment, a system includes a first power converter or source configured to provide power to a bus, a second power converter or source configured to provide power to the bus, and a load electrically coupled to the bus. The system also includes a controller configured to adjust a droop resistance associated with the first power source according to a continuous non-linear function based on an amount of current supplied to the load by the first power source. The system can also include a second controller configured to adjust a droop resistance associated with the second power source according to the continuous non-linear function (or another continuous non-linear function). The use of the continuous non-linear functions achieves tighter voltage regulation particularly at lower loads and better load sharing at higher loads.


Patent
Virginia Polytechnic Institute, State University, Sano Inc, Arena, Verbridge and Davalos | Date: 2017-03-22

A system and method for selectively treating aberrant cells such as cancer cells through administration of a train of electrical pulses is described. The pulse length and delay between successive pulses is optimized to produce effects on intracellular membrane potentials. Therapies based on the system and method produce two treatment zones: an ablation zone surrounding the electrodes within which aberrant cells are non- selectively killed and a selective treatment zone surrounding the ablation zone within which target cells are selectively killed through effects on intracellular membrane potentials. As a result, infiltrating tumor cells within a tumor margin can be effectively treated while sparing healthy tissue. The system and method are useful for treating various cancers in which solid tumors form and have a chance of recurrence from microscopic disease surrounding the tumor.


Patent
Virginia Polytechnic Institute and State University | Date: 2016-09-29

Capacitors connected between gate terminals of a plurality of parallel-connected power transistors are charged and discharged in each switching cycle to provide a plurality of power transistor control waveforms from a single gate driver waveform that equalize power losses/temperatures or steady-state currents among the plurality of power transistors. The capacitors are charged to different voltages by diverting current from one transistor driver by disabling another power transistor driver at different respective times in response to measured transient or steady state current or temperature or other operational parameter.


Patent
Virginia Polytechnic Institute and State University | Date: 2017-02-28

The present invention provides a novel chimeric porcine circovirus infectious DNA clone and live attenuated chimeric virus with the PCV2, preferably of subtype PCV2b, capsid gene integrated into a non-pathogenic PCV1 virus genome. In a particular embodiment, the PCV2 capids gene is of subtype PCV2b, the predominant subtype circulating in pigs worldwide. The attenuated chimeric virus, designated PCV1-2b, effectively protects pigs from PCV2b challenges, and can be used as a live vaccine, as well as an inactivated (killed) vaccine, that provides protection and cross protection against PCV2b and PCV2a subtypes infection. The live attenuated vaccine of the present invention is also effective protecting pigs from porcine circovirus-associated disease (PCVAD).


Patent
Virginia Polytechnic Institute and State University | Date: 2017-07-19

Provided herein is a multivalent Brucella vaccine expressing at least one heterologous M. tuberculosis antigen. The vaccines described herein serve as an environmentally safe bivalent vaccine for protection against Brucella and Mycobacterium infections simultaneously. In particular, a multivalent vaccine comprising a Brucella strain transformed with a vector that expresses at least one M. tuberculosis antigen, where the M. tuberculosis antigen(s) is codon optimized for the Brucella strain is provided. In some aspects, the Brucella strain is B. abortus strain RB51 leuB and the M. tuberculosis antigen is one or more of Ag85B, Rv2660c, and ESAT6.


Patent
Virginia Polytechnic Institute and State University | Date: 2017-02-03

The present invention provides engineered tissue scaffolds, engineered tissues, and methods of using them. The scaffolds and tissues are derived from natural tissues and are created using non-thermal irreversible electroporation (IRE). Use of IRE allows for ablation of cells of the tissue to be treated, but allows vascular and neural structures to remain essentially unharmed. Use of IRE thus permits preparation of thick tissue scaffolds and tissues due to the presence of vasculature within the scaffolds. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation.


Patent
Virginia Polytechnic Institute and State University | Date: 2017-07-26

Described herein are stem cells and stem cell compositions that can be used to treat soft tissue injuries, including tendon and ligament injuries. Also described herein are cellular scaffolds that can contain a stem cell or stem cell compositions described herein. Also described herein are soft tissue bioreactor devices. Also described herein are methods of using the stem cells, stem cell compositions, and soft tissue bioreactors and methods of treating tendon and ligament injuries.


Patent
Virginia Polytechnic Institute and State University | Date: 2017-01-27

In one example, an omnidirectional wireless power transfer system includes high frequency power generator configured to generate a supply of high frequency oscillating power, a number of transmitter-side resonant tank circuits electrically coupled to the high frequency power generator, a receptacle including a number of coils arranged for omnidirectional power transfer to an electronic device placed in the receptacle, and a controller configured to activate individual ones of the transmitter-side resonant tank circuits to wirelessly transmit power to the electronic device through near-field resonant inductive coupling. In one example, the receptacle can be embodied as a bowl, and the controller can activate individual ones of the transmitter-side resonant tank circuits over time to generate an omnidirectional field distribution for wireless power transmission. In other aspects, various transmitter-side and receiver-side tank circuits for coupling independent resonance and ZVS operation are described.

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