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Aurangābād, India

Thore S.N.,Vinayakrao Patil College | Gupta A.K.,Vinayakrao Patil College
Oriental Journal of Chemistry | Year: 2010

Various fluorine containing (42)-2-(4-fluorophenyl)-4-[(1 -phenyl-1Hoyrazol-4-yl)methylidene]5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3- one 3a-e, (4E)-2-(4-fluorophenyl)-4-((4-oxo-3,4-dihydro2Hohromerh3-yl) methylidene]-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one 5a-e and (4E)-4-[(2chloroquinolin-3-yl)methylidene]-2-(4-fluorophenyl)-5-(trifluromethyl) -2,4-dihydro-3H-pyrazol-3-one 7ae have been synthesized. The compounds have been characterized by IR, 1H, NMR, MS study and further confirmed by elemental analysis.


Thore S.N.,Vinayakrao Patil College | Gupta A.K.,Vinayakrao Patil College
Indian Journal of Heterocyclic Chemistry | Year: 2010

Different aryl isothiocyanates on reaction with acid hydrazides gave thiosemicarbazides. These thiosemicarbazides on treatment with cone. H 2SO 4 gave thiadiazoles. Their structures were confirmed by spectral analysis. The compounds synthesized were screened for their antibacterial activity against seven different organisms by using Agar Diffusion Bioassay method. They were also tested for antifungal activity.


Thore S.N.,Vinayakrao Patil College | Gupta A.K.,Vinayakrao Patil College
Indian Journal of Heterocyclic Chemistry | Year: 2010

The acid catalyzed cyclization of β-diketones gave chromones 6. The key step is esterification of acrylic acid with 2-hydroxyacetophenone to give ester 4. The structures of the products were confirmed by NMR, IR and mass spectral data.


Thore S.N.,Vinayakrao Patil College | Gupta A.K.,Vinayakrao Patil College
Indian Journal of Heterocyclic Chemistry | Year: 2010

Condensation of acetophenone with pyrazole aldehyde gave new series of fluorine and chlorine containing chalcones 3. Several pyrazolyl compounds were obtained using compounds 3. The structures of the compounds 3-7 were confirmed by NMR, IR and mass spectroscopy.

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