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"We hope the money raised will help The Sick Children’s Trust continue its great work and reach out to more families who needs its support.” The North East regional branch of The Institution of Mechanical Engineers (IMechE) has raised an outstanding £5,050 for The Sick Children’s Trust from its annual Chairman’s dinner held earlier this month. IMechE North East Chairman Chris Briggs chose The Sick Children’s Trust as the chosen charity for the event and hoped to raise £2,500 for the charity which supports families with children undergoing lifesaving treatment. However, following generous donations from attendees, a superb raffle and auction the evening doubled the initial fundraising target, raising over £5,000. The Sick Children’s Trust runs ten ‘Homes from Homes’ across the country supporting families with seriously ill children in hospital. Two of its ‘Homes from Home’ are located in Newcastle upon Tyne at the Royal Victoria Infirmary and Freeman Hospital. The money raised from the North East IMechE dinner will go towards running both ‘Homes from Home’ in the North East. Chris Briggs says: “We’d like to say a huge thank you to our sponsors, British Engines, and all our guests for making the event at Hardwick Hall such a huge success. Because of everyone’s support, we were able to raise more than double our target for The Sick Children’s Trust, a charity that helps so many families going through the most traumatic times. We hope the money raised will help The Sick Children’s Trust continue its great work and reach out to more families who needs its support.” The Sick Children’s Trust supports over 4,000 families with seriously ill children in hospital every year. Caroline O’Doherty, Campaigns and Appeals Manager at The Sick Children’s Trust says: “We’re absolutely delighted with the tremendous amount raised. The guests were so generous with their donations and we simply can’t thank Chris and the rest of the IMechE members enough for choosing The Sick Children’s Trust as the benefiting charity of the dinner. “Thanks to everyone’s generosity, we can be there for the increasing number of families from the North East and beyond who rely on us to keep them together with their sick child.” For more information about The Sick Children’s Trust, please visit:

News Article | May 5, 2017

Researchers from Newcastle University in the United Kingdom and Stiefel - a GlaxoSmithKline company - report their findings in the Journal of Allergy and Clinical Immunology. Lead investigator Nick Reynolds, a professor of dermatology at Newcastle University who also works as a skin and eczema specialist in Newcastle's Royal Victoria Infirmary, says that their discovery "reinforces the importance of filaggrin deficiency leading to problems with the barrier function in the skin and predisposing someone to eczema." He and his colleagues also believe that the study could lead to the development of drugs that target the underlying causes of eczema rather than just alleviate the symptoms. Eczema is a condition that is usually characterized by dry, itchy, cracked, and rough skin that mainly erupts on the hands, feet, and face, as well as behind the knees and inside the elbows. It can also present with blisters that weep fluid when scratched. The condition can cause disturbed sleep and may profoundly affect quality of life. The most common type of eczema is an inflammatory, non-contagious skin condition called atopic dermatitis that affects around 30 percent of people in the United States, most of them children and adolescents. In this article, the word eczema refers specifically to atopic dermatitis. The exact causes of eczema are unknown. However, research reveals that it is likely to arise from a combination of genetic and environmental factors and probably involves dysfunction of both the skin barrier and the immune system. People with eczema may also develop asthma and hay fever. In their study report, the researchers explain that filaggrin plays a key role in maintaining the barrier that protects the skin and that previous research has already established that a lack of the protein strongly predisposes people to eczema. However, exactly what happens at the molecular level to link filaggrin deficiency to the development of eczema "remains incompletely understood," they note. To further investigate the role of filaggrin, the researchers developed a 3-D model of human skin, in which, using molecular tools, they made the epidermis (the outside layer) deficient in filaggrin. The model closely mimics what happens in the skin of people with eczema. Using the model, the researchers were able to map the proteins and signaling pathways that lie "downstream" of filaggrin, and thus observe how the absence of the protein altered them. They identified a number of signaling mechanisms that regulate inflammation, cell structure, stress response, and the function of the skin barrier. The mapping of these pathways in the model appears to match that seen in people with eczema. For example, the skin of people with active eczema has high levels of a protein coded by the gene KLK7. The team was able to show - from the model - that upregulation of KLK7 was one of the molecular consequences of filaggrin loss. Learn how friendly skin bacteria keep harmful Staphylococcus aureus in check.

The North East regional branch of IMechE will hold their annual Chairman's Dinner on 12 May to raise money for The Sick Children's Trust The North East regional branch of an international engineering society has chosen The Sick Children’s Trust to benefit from its prestigious annual dinner next month. The Institution of Mechanical Engineers (IMechE), which represents over 115,000 members worldwide, has chosen The Sick Children’s Trust to benefit from its regional annual charity dinner on Friday 12 May at Hardwick Hall Hotel in Sedgefield. The organisers of the event, which celebrates the achievements of its members in the North East, are hoping it will raise over £2,500 for the charity which supports families with seriously ill children in hospital with ‘Home from Home’ accommodation. The Sick Children’s Trust runs two ‘Homes from Home’ in Newcastle upon Tyne, supporting thousands of families from across the North East when their child is undergoing lifesaving treatment at both the Freeman Hospital and Royal Victoria Infirmary. IMechE North East Chairman Chris Briggs, says: “We are thrilled to be supporting The Sick Children’s Trust. We always choose a charity active in the region and The Sick Children’s Trust helps so many families who have children in hospital in Newcastle. We hope by choosing them as our benefitting charity, our guests will dig deep to help the charity help even more families with seriously ill children in hospital.” The dinner is the keynote event in the IMechE’s Regional calendar, and is sponsored once again by British Engines Ltd. Guests who attend can expect a fantastic evening, with guest speaker Kevin Connelly, the celebrated impressionist from TV's 'Dead Ringers' and a four-course dinner with wine. The evening promises to be a great opportunity to network with peers from across the engineering community. The Sick Children’s Trust runs ten ‘Homes from Home’ across the country supporting, over 4,000 families with seriously ill children in hospital every year. Although ‘Home from Home’ accommodation is provided free to families, it costs the charity £30 to support a family for one night. Caroline O’Doherty, Campaigns and Appeals Manager at The Sick Children’s Trust says: “We were delighted when Chris told us that we were IMechE’s chosen charity for the annual dinner. The money raised from the event will go a long way towards providing families in the region with a ‘Home from Home’ when their child is undergoing lifesaving treatment in hospital. We’d like to say a huge thank you to IMechE for choosing to support us; thanks to your generosity, we can be there for the increasing number of families who rely on us to keep them together with their sick child..” Ticket sales for the dinner are now closed but it’s still possible to make a donation to the charity at For more information: Please contact Alexandra Glatman on 0207 337 2213 or email [email protected]

Flin R.,University of Aberdeen | Patey R.,University of Aberdeen | Glavin R.,Victoria Infirmary | Maran N.,Royal Infirmary
British Journal of Anaesthesia | Year: 2010

This review presents the background to the development of the anaesthetists' non-technical skills (ANTS) taxonomy and behaviour rating tool, which is the first non-technical skills framework specifically designed for anaesthetists. We share the experience of the anaesthetists who designed ANTS in relation to applying it in a department of anaesthesia, using it in a simulation centre, and the process of introducing it to the profession on a national basis. We also consider how ANTS is being applied in relation to training and research in other countries and finally, we discuss emerging issues in relation to the introduction of a non-technical skills approach in anaesthesia. © The Author [2010].

Fioratou E.,University of Aberdeen | Flin R.,University of Aberdeen | Glavin R.,Victoria Infirmary | Patey R.,Royal Infirmary
British Journal of Anaesthesia | Year: 2010

Situation awareness (SA) is one of the essential non-technical skills for effective and safe practice in high-risk industries, such as healthcare; yet, there is limited research of its significance in anaesthetic practice. In this paper, we review this scant research that focuses on SA as patient monitoring alone and advocate for a more comprehensive view of SA in anaesthetic practice and training that extends beyond monitoring, namely, a distributed cognition approach. We identify further factors influencing anaesthetists' SA and provide a case that resulted in an anaesthetic fatality to illustrate the application of an alternative view of SA in anaesthesia. Distributed SA in anaesthetic practice provides the foundation for further research that may in turn influence the teaching and assessment of this important non-technical skill. © The Author [2010].

Glavin R.,Victoria Infirmary | Flin R.,University of Aberdeen
Canadian Journal of Anesthesia | Year: 2012

Purpose: We look at the changing nature of medical education in the developed world with particular reference to those areas of the new curriculum frameworks which have introduced topics from the psychosocial realm. Principle findings: Research in the branch of psychology dealing with human factors has developed a useful body of working knowledge which applies to other industries where humans interact with the complex systems in which they function. Some findings are already being applied to facets of anesthesia performance, including situation awareness, effective teamwork, countermeasures against active errors and latent pathogens, and limitations of human performance. However, existing lessons and practices from industrial or military research may not translate directly into effective strategies for anesthesiologists. Collaborative studies between psychologists and clinicians should continue in order to provide the anesthetic curriculum with an effective body of knowledge for each role of the anesthesiologist. Although individual anesthesiologists have made important contributions in this field, such material has not been formally incorporated into the curricula serving anesthesiologists in the developed world. Conclusions: There is a gap between the human factors psychologists now know and the human factors anesthesiologists need to know. As that gap closes, anesthesiologists may come to think more like human factor psychologists as well as biomedical scientists. © 2011 Canadian Anesthesiologists' Society.

Glavin R.J.,Victoria Infirmary
Best Practice and Research: Clinical Anaesthesiology | Year: 2011

A key role in anaesthetic practice is gathering and assimilating information from a variety of sources to construct and maintain an accurate mental model of what is happening to the patient, a model that will influence subsequent decisions made by the anaesthetist on the patient's behalf, as part of a larger team. Effective performance of this role requires a set of mental functions that place great demands upon the physiology and psychology of anaesthetists, functions that are vulnerable to a wide range of factors including those affecting team performance and those affecting the anaesthetist specifically. The number of tasks, their complexity, the physical and mental demands of the job, the underlying health and well-being of the anaesthetist and the environment and context within which the team attempt to meet the demands placed on them will influence the outcome of patient care. © 2011 Elsevier Ltd. All rights reserved.

Larkin J.,Victoria Infirmary
Scottish Medical Journal | Year: 2012

Fibromyalgia has always struggled to be taken seriously. The vague mixture of aches, pains, stiffness and fatigue with no clear clinical or investigational findings has led many to doubt its very existence. Evidence is accumulating, however, of demonstrable abnormalities of pain processing and psychosocial factors in fibromyalgia subjects. These may 'prove' its existence, but do they suggest it is rheumatological?

Wellington B.,Victoria Infirmary
International Journal of Orthopaedic and Trauma Nursing | Year: 2010

Small but significant numbers of adults sustain a traumatic brachial plexus injury, often resulting in devastating disability affecting their physical and psychological well being. There is limited evidence of qualitative research available and this paper reports on a study that considers the patient's own experience of living with this injury. Patients were selected using purposive sampling from those who were on the database for the Scottish National Brachial Plexus Injury Service. Five patients were finally selected and data collected using semi-structured audio taped interviews and field notes. Similar themed categories were identified from the experiences described by the patients including employment, pain, body image and sexuality/emotions.Recommendations include timely and ongoing pain management reviews and initial counselling sessions for all new patients. © 2009 Elsevier Ltd.

Glavin R.J.,Victoria Infirmary
British Journal of Anaesthesia | Year: 2010

Medication errors are common throughout healthcare and result in significant human and financial cost. Prospective studies suggest that the error rate in anaesthesia is around one error in every 133 anaesthetics. There are several categories of medication error ranging from slips and lapses to fixation errors and deliberate violations. Violations may be more likely in organizations with a tendency to blame front-line workers, a tendency to deny the existence of latent conditions, and a blinkered pursuit of productivity indicators. In these organizations, borderline-tolerated conditions of use may occur which blur the distinction between safe and unsafe practice. Latent conditions will also make the error at the 'sharp end' more likely to result in actual patient harm. Several complementary strategies are proposed which may result in fewer medication errors. At the organizational level, developing a safety culture and promoting robust error reporting systems is key. The individual anaesthetist can play a part in this, setting an example to other members of the team in vigilance for errors, creating a safety climate with psychological safety, and reporting and learning from errors. © The Author [2010].

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