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Songgang-dong, South Korea

Kim H.-K.,Veterans Health Service Medical Center | Kim H.-K.,Seoul National University | Kim S.-H.,Seoul National University
Dental Materials

Objective This study was aimed to investigate the effect of the number of coloring liquid applications on the optical properties of monolithic zirconia. Methods Eighteen monolithic zirconia specimens (27.6 mm × 27.6 mm × 2.0 mm) were fabricated and divided into 6 groups (n = 3). Each group was designated by the number of A2-coloring liquid applications (Group I to Group V) and Group O as a control. Color and spectral distribution of the specimens were measured with a double-beam spectrophotometer. CIE L*, a* and b* relative to the standard illuminants D65 were measured in reflectance and transmittance modes. Color difference (ΔEab*), translucency parameter (TP) and opalescence parameter (OP) were calculated. All measurements were performed on five different areas of each specimen. All data were analyzed by ANOVA and multiple comparison Scheffé test, Pearson correlations and linear regression analysis (α = 0.05). Results With the increase of the number of coloring liquid applications, CIE L* (R2 = 0.878) and OP values (R2 = 0.701) were decreased, but CIE b* (R 2 = 0.938) was increased. However, TP values were not significantly changed. The color differences among groups ranged from 1.3 to 15.7 ΔEab* units. Strong correlation was found between OP and Δb* (R2 = 0.982, P <.01). Significance Within the limitations of this study, it can be concluded that the number of coloring liquid applications with a single shade affects the lightness, yellow chromaticity and opalescence of monolithic zirconia, although its translucency cannot be controlled by the coloring procedure. © 2014 Academy of Dental Materials. Source

Choi G.W.,Korea University | Kim H.J.,Korea University | Yeo E.D.,Korea University | Yeo E.D.,Soonchunhyang University | And 2 more authors.
Bone and Joint Journal

In a retrospective study we compared 32 HINTEGRA total ankle replacements (TARs) and 35 Mobility TARs performed between July 2005 and May 2010, with a minimum follow-up of two years. The mean follow-up for the HINTEGRA group was 53 months (24 to 76) and for the Mobility group was 34 months (24 to 45). All procedures were performed by a single surgeon. There was no significant difference between the two groups with regard to the mean AOFAS score, visual analogue score for pain or range of movement of the ankle at the latest follow-up. Most radiological measurements did not differ significantly between the two groups. However, the most common grade of heterotopic ossification (HO) was grade 3 in the HINTEGRA group (10 of 13 TARs, 76.9%) and grade 2 in the Mobility group (four of seven TARs, 57.1%) (p = 0.025). Although HO was more frequent in the HINTEGRA group (40.6%) than in the Mobility group (20.0%), this was not statistically significant (p = 0.065).The difference in peri-operative complications between the two groups was not significant, but intra-operative medial malleolar fractures occurred in four (11.4%) in the Mobility group; four (12.5%) in the HINTEGRA group and one TAR (2.9%) in the Mobility group failed (p = 0.185). © 2013 The British Editorial Society of Bone & Joint Surgery. Source

Kim Y.,Veterans Health Service Medical Center | Park C.J.,University of Ulsan | Roh J.,University of Ulsan | Huh J.,University of Ulsan
Korean Journal of Pathology

Primary effusion lymphoma (PEL) is a human herpes virus 8 (HHV8)-positive large B-cell neoplasm that presents as an effusion with no detectable tumor in individuals with human immunodeficiency virus infection or other immune deficiencies. PEL is an aggressive neoplasm with a poor prognosis. PEL cells show diverse morphologies, ranging from immunoblastic or plasmablastic to anaplastic. The immunophenotype of PEL is distinct, but its lineage can be misdiagnosed if not assessed thoroughly. PEL cells usually express CD45, lack B- and T-cell-associated antigens, and characteristically express lymphocyte activation antigens and plasma cell-associated antigens. Diagnosis of PEL often requires the demonstration of a B-cell genotype. HHV8 must be detected in cells to diagnose PEL. In most cases, PEL cells also harbor the Epstein-Barr virus (EBV) genome. Similar conditions associated with HHV8 but not effusion-based are called "extracavitary PELs." PELs should be differentiated from HHV8-negative, EBV-positive, body cavity-based lymphomas in patients with long-standing chronic inflammation; the latter can occur in tuberculous pleuritis, artificial pneumothorax, chronic liver disease and various other conditions. Despite their morphological similarity, these various lymphomas require different therapeutic strategies and have different prognostic implications. Correct diagnosis is essential to manage and predict the outcome of patients with PEL and related disorders. © 2014 The Korean Society of Pathologists/The Korean Society for Cytopathology. Source

Kim W.-S.,Veterans Health Service Medical Center | Kim W.-S.,Korea University
Human Movement Science

This study was performed to investigate whether components from trunk progression (TP) and step length were related to step length asymmetry in walking in patients with hemiparesis. Gait analysis was performed for participants with hemiparesis and healthy controls. The distance between the pelvis and foot in the anterior-posterior axis was calculated at initial-contact. Step length was partitioned into anterior foot placement (AFP) and posterior foot placement (PFP). TP was partitioned into anterior trunk progression (ATP) and posterior trunk progression (PTP). The TP pattern and step length pattern were defined to represent intra-TP and intra-step spatial balance, respectively. Of 29 participants with hemiparesis, nine participants showed longer paretic step length, eight participants showed symmetric step length, and 12 participants showed shorter paretic step length. For the hemiparesis group, linear regression analysis showed that ATP asymmetry, AFP asymmetry, and TP patterns had significant predictability regarding step length asymmetry. Prolonged paretic ATP and shortened paretic AFP was the predominant pattern in the hemiparesis group, even in participants with symmetric step length. However, some participants showed same direction of ATP and AFP asymmetry. These findings indicate the following: (1) ATP asymmetries should be observed to determine individual characteristics of step length asymmetry, and (2) TP patterns can provide complementary information for non-paretic limb compensation. © 2016 Elsevier B.V. Source

Lee C.S.,Seoul National University | Lee S.D.,Korean Armed Forces Capital Hospital | Kang S.-H.,Veterans Health Service Medical Center | Park H.Y.,Seoul National University | Yoon I.-Y.,Seoul National University
European Journal of Neurology

Background and purpose: It is not clear which is preferred between iron supplement and a dopamine agonist in the treatment of restless legs syndrome (RLS) with iron deficiency. The efficacies of oral iron supplementation and pramipexole for treatment of RLS with low-normal serum ferritin (15-50 ng/ml) were compared. Methods: Thirty RLS patients who took either oral iron or pramipexole for 12 weeks and were followed at 2, 4, 8 and 12 weeks after treatment commencement were enrolled. Severities of RLS symptoms were assessed using the international RLS study group rating scale for severity (IRLS) at every visit. Treatment response was defined as a decrease in IRLS score of at least 50% from baseline. Results: The 30 subjects were assigned equally to an iron or pramipexole group. At baseline, IRLS scores and serum ferritin levels were similar between these two groups. After 12 weeks, IRLS scores were lower than those at baseline in both groups (iron -9.1 ± 7.07, P < 0.001; pramipexole -8.7 ± 8.31, P = 0.001) and similar between the two groups. Changes in IRLS scores from baseline were similar between the two groups at each visit. The response rates of the groups were identical at 46.7%. Conclusions: Pramipexole was not different from oral iron in terms of efficacy and improvement speed in RLS patients with a low-normal serum ferritin, but response rate of either oral iron or pramipexole alone was moderate. Some proportion of RLS patients with iron deficiency might benefit from combined use of oral iron and dopamine agonists. © 2013 The Author(s) European Journal of Neurology © 2013 EFNS. Source

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