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Timişoara, Romania

Ledeti I.,Victor Babes University of Medicine and Pharmacy Timisoara | Ledeti I.,Vest University of Timisoara | Vlase G.,Vest University of Timisoara | Vlase T.,Vest University of Timisoara | And 5 more authors.
Revista de Chimie | Year: 2015

Thermal analysis (TG/DTG/HF) and spectroscopic tool (such as FTIR) are useful instrumental techniques that have been successfully employed in the development of pharmaceutical research, revealing important information over the physico-chemical properties of active pharmaceutical ingredients such as purity and stability, polymorphic transitions and as well their behaviour in binary mixtures with other active pharmaceutical ingredients or excipients. In this study, the antihypercholesterolemic drug lovastatin (LOV) was studied by TG/DTG/HF, but as well Fourier transform infrared spectroscopy, as pure API and as well in binary mixtures with three common pharmaceutical excipients - magnesium citrate, lactose monohydrate and fumed silica. Source


Craciunescu C.M.,Polytechnic University of Timisoara | Ercuta A.,Polytechnic University of Timisoara | Ercuta A.,Vest University of Timisoara | Mitelea I.,Polytechnic University of Timisoara | Budau V.,Polytechnic University of Timisoara
AIP Conference Proceedings | Year: 2013

The work details the results on measuring the internal friction and the observation of the correlation with the phase transformation in shape memory alloys explored using an Acoustic Elastometer. The simultaneous exploration of the internal friction and actuation during heating and cooling of several alloy families are discussed based on the specific phase transformations that occur in each alloy. The influence of the thermomechanical history of the investigated alloys is also accounted in the interpretation of the results. The measurement of the free end of cantilever-type samples as a function of temperature, based on capacitive measurement during the thermal cycling is taken as a base for the discussion of the effects of the phase transformations on the resulting actuation. © 2013 AIP Publishing LLC. Source

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