Vel Technology Multitech Engineering College

Chennai, India

Vel Technology Multitech Engineering College

Chennai, India
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Priya G.,Sathyabama University | Chellaram C.,Vel Technology Multitech Engineering College
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2014

Objective: To develop a protocol for culturing callus and regenerate shoots invitro from the leaf of Solanum trilobatum and study its antihepatocarcinogenic effect in an animal model. Methods: Surface sterilized explants (0.5-1.0 cm) length were placed on the MS basal medium supplemented with various concentrations of 2, 4 D (0.45, 2.26, 4.52, 11.31 and 12.56 μM), NAA (0.54, 1.34, 2.69, 5.37, 13.43 and 26.85 μM), BA (0.44, 1.11, 2.22, 4.44, 8.88 and 13.32 μM) for callus induction. MS basal medium supplemented with 10% coconut milk and various concentrations of BAP (2.2 - 22 μM) dissolved in ethanol was used for shoot initiation. Rats divided into four groups were administered with DEN and DEN (200 mg/kgbwt) i.p along with methanol extracts of leaves, callus and shoot of S.T (250 mg/kgbwt) orally for 3 months. Results: Rats administered with DEN showed significant deviation (p < 0.05) of marker enzymes ALT, AST, LDH and TB in the serum. Conclusion: Administration of crude extracts of leaf, callus and shoot of S.T offers better protection against hepatocellular carcinoma.


Anand P.T.,Vel Technology Multitech Engineering College | Chellaram C.,Vel Technology Multitech Engineering College | Shanthini C.F.,Madras Christian College | Sivakumar R.,Vel Technology Multitech Engineering College
Journal of Chemical and Pharmaceutical Research | Year: 2013

Competition amongst microbes for space and nutrients in the marine environment is a powerful selective force which has led to the evolution of a variety of effective strategies for colonizing and growing on surfaces. As the primary role of antimicrobial activity can be to antagonize competitors, bacteria may also produce antimicrobial compounds when they sense the presence of competing organisms. Bacterium - bacterium antagonistic interactions involving antibiotics are well documented in soils but work relating to this in marine environment is scanty. In this present study marine bacterial strains were induced for enhancement as well as for antibiotic production. In the present study out of the 75 antibiotic non-producer strains used for inducement study, 20 strains were induced. Inducements of antibiotic production by the bacterial strains were carried with heat killed and live Escherichia coli and Pseudomonas aeroginosa cells.


Anitha T.,Vel Technology Multitech Engineering College | Arunudaya R.,Sriram Engineering College | Nivetha N.U.,Sriram Engineering College
International Journal of Control Theory and Applications | Year: 2017

In the Mobile IPv6 (MIPv6) convention, a portable node (PN) is a mobile device with a permanent home address (HoA) on its home connection. The PN will obtain a care-of address (CoA) when it meanders into a remote connection. It then sends a coupling upgrade (CU) message to the home specialist (HS) and the correspondent hub (CH) to advise them of its current CoA so that future information packets bound for its HoA will be sent to the CoA. In Mobile IPv6 course enhancement with secure tunneling encryption based restricting upgrade (STERU) calculation is utilized. It permits the bundle to cross a shorter course than the default one through the Home Agent. In Route Evolution (RE), the companion hub takes in an authoritative between the Mobile Node's perpetual Home Address and its present transitory Care-of-Address. Once such a coupling is set up, the companion hub will send all parcels whose goal is the Home Address to the Careof- Address. The BU message is defenseless against a few security assaults; STERU is proposed to defeat this security issue. To guarantee that the transmission of BU information is more secure, we use asymmetric cryptography and it gives digital signature that can be utilized for client information confirmation. It permits the CH to approve that the MN is not a vindictive node. © International Science Press.


Mohanasundaram K.,Vel Technology Multitech Engineering College
International Journal of Control Theory and Applications | Year: 2016

The main objective of this paper is for saving the human lives and improving the safety and reliability of Aircrafts. To locate an aircraft more easily in case of accident.The flight section has microcontroller, rechargeable battery, water sensor, LCD, and ejection mechanism. Whenever the flight falls into the sea, water sensor will start sensing and give command signal to microcontroller to eject the floatable object from flight with current GPS value of flight. The Black box ejects out into the water to collect the information about latitude and longitude of the position and all the data about the flight are sent to the Zigbee and through the serial transmission it is transmitted to the Ground Station. The proposed system will be overcoming the all disadvantages in Existing system, it includes mainly time delay in finding the black box, Spending cost for Sending the search teams. In this paper, It includes dividing the area into particular segments for continuous communication between airplane and the Rescue section, which means the earth station. The Results are implemented also with Simulation outputs. © International Science Press.


Priya G.,Sathyabama University | Chellaram C.,Vel Technology Multitech Engineering College
Asian Journal of Pharmaceutical and Clinical Research | Year: 2014

Objective: To analyze the antioxidant and antiproliferative potential of Solanum trilobatum was evaluated. Methods: Free radical scavenging potential of the plant was studied by various in vitro assays such as DPPH, ßCarotene and Frap assay. The antiproliferative activity of Solanum trilobatum was analysed by MTT assay. Result: The ethanol extract is more powerful in scavenging free radicals. The preliminary phytochemical screening of Solanum trilobatum revealed the presence of phenolics, carbohydrates alkaloids, flavonoids and tannins in high amount. The antiproliferative potential of the ethanol extract was studied on Hep2 cell lines by MTT assay. The extract had an IC50 value of100μg/mL which showed cell viability of 22.67%. From the result, it is clear that ethanol extract of Solanum trilobatum has cytotoxic effect on Hep2 cell lines. Conclusion: Thus, the study revealed that Solanum trilobatum could be considered as a significant source of antioxidant and antiproliferative agents.


Prem Anand T.,Vel Technology Multitech Engineering College | Chellaram C.,Vel Technology Multitech Engineering College | Sivakumar R.,Vel Technology Multitech Engineering College | Felicia Shanthini C.,Madras Christian College
Biosciences Biotechnology Research Asia | Year: 2013

Marine microbes use a variety of strategies to colonize both animate as well as inanimate surfaces in marine environment. The competition among microbes to colonize surfaces acts as a potent selective force. One of the important strategies these microbes use is the secretion of antimicrobial compounds, which helps to inhibit the growth of the competitors. Bacterium - bacterium antagonistic interactions involving antibiotics are well documented in soils but work relating to this in marine environment is scanty. In this present study 75 antibiotic producing bacterial strains were challenged to enhance the production of antibiotics by these strains. Enhancement of antibiotic production by the producer strain was carried out by inducing the producer strains with heat killed and live Escherichia coli and Pseudomonas aeruginosa cells. Out of the 75 induced strains 21 strains were found to enhance their antibiotic production. In the search for novel antibiotics from marine bacteria, these strategy can be used to enhance production of the potent compounds to overcome the problem of low yield to a certain degree.


Priya G.,Sathyabama University | Chellaram C.,Vel Technology Multitech Engineering College
International Journal of Pharma and Bio Sciences | Year: 2014

The ethanolic leaf extracts of Solanum trilobatum plant were used for antibacterial study by disc diffusion method. Different concentrations (10mg/ml, 20mg/ml, 30mg/ml) of the concentrated ethanolic leaf extract were tested for its antibacterial activity against bacterial strains such Bacillusubstilis, Staphylococcus aureus, Bacillus cereus, E. Cali & Pseudomonas aeruginosa. The bacterial cultures were grown in Muller hinton agar and Muller hinton broth. The zone of inhibition was comparatively more in the concentration of 30mg/ml. Phytochemical screening of the ethanolic leaf extract of the plant revealed the presence of tannins, saponins, flavonoids, carbohydrates and alkaloids. Thin Layer Chromatography (TLC) value of the leaf extract showed the highest Retention Factor (RF) value. The plant extracts showed better inhibitory activity against the tested organisms.


Govindarajan P.,Sathyabama University | Chinnachamy C.,Vel Technology Multitech Engineering College
Pakistan Journal of Pharmaceutical Sciences | Year: 2014

This study focuses on the phytochemical properties and the anti-hepatocarcinogenic effects of the leaf and in vitro-derived callus and shoot extracts of Solanum trilobatum. In the leaf, callus and shoot, the presence of sugar, proteins, alkaloids, flavonoids, saponins, tananins, cardiacglycoside, terpenoid and lipids was established by preliminary phytochemical screening. Surface-sterilized explants (0.5-1.0 cm) were placed on the MS basal medium supplemented with different concentrations of 2,4-dichlorophenoxyacetic acid (0.45, 2.26, 4.52, 11.31 and 12.56μM), naphthylacetic acid (NAA; 0.54, 1.34, 2.69, 5.37, 13.43 and 26.85μM) and 6-benzylaminopurine (BA; 0.44, 1.11, 2.22, 4.44, 8.88 and 13.32μM) for callus induction. Explants from node and callus culture were inoculated on the MS basal medium supplemented with varying concentrations of BA (0.44-22.20 μM) and NAA (0.54-10.74μM) for shoot multiplication. Rats were divided into five groups and administered with diethyl nitrosamine (DEN) and DEN (200mg/kg bwt) intraperitoneally along with methanol leaf and in vitro-derived callus and shoot extracts (250mg/kg bwt) orally for 3 months. A significant deviation (P<0.05) in marker enzymes such as alanine transaminase, aspartate transaminase, lactate dehydrogenase and total bilirubin was found in rats administered with DEN. The liver tissue was used for the analysis of glutathione reductase, lipid peroxidation, glutathione peroxidase, glutathione S-transferase, superoxide dismutase and catalase. DEN administration caused a significant elevation in serum enzymes and total bilirubin. Moreover, antioxidant enzymes were drastically inhibited with significant reduction in glutathione and increased lipid per oxidation. Increased glutathione level and reduced lipid peroxidation were also evident in S. trilobatum-treated rats. However, crude S. trilobatum and in vitro-derived callus and shoot extracts offered better protection against free radical toxicity induced by DEN.


Sakthiselvam J.,Vel Technology Multitech Engineering College | Mohanram S.,Vel Technology Multitech Engineering College
International Journal of Control Theory and Applications | Year: 2016

In current scenario many of the people are suffering from seizure, fit and cramps. People suffering from the above mentioned causes can be easily slipped down without control in the current place itself. In our project we present the human activity monitoring system for fall accident and health parameters detection. The system consists of wearable blood pressure, temperature and two Accelerometer sensors. If an abnormal event is detected the information will be conveyed to the emergency contact number of the patient and that information is passed to the nearest ambulance station through wireless transceiver. This system also can be monitored through mobile application and provides the current status, location of the patient. © International Science Press.


Rekha S.S.,VEL Technology MULTITECH Engineering College | Immanuvel K.A.J.,VEL Technology MULTITECH Engineering College
Advanced Materials Research | Year: 2014

Nowadays, renewable energies have been widely applied to achieve eco friendly objectives. This paper presents the development of a single-phase grid-connected wind energy generation with the improvement in power quality and efficiency. This mainly focuses on showing the improvement in power quality by overcoming the drawbacks with the existing wind energy generation based on the PLL with the discrete PI controller. It is found that Total Harmonic Distortions (THD) present in PLL Single-phase grid-connected wind energy generation can be reduced by using modified PLL method. The modified wind energy generation is based on PLL with Fuzzy logic controller instead of PLL with discrete PI controller. The PLL gets input from the load side, and compare with any one parameters current or voltage (closed loop system). The aim of this survey is to propose a new topology in (HCM) HILL CLIMB METHOD. The tasks related to the SVPWM algorithm, the PLL, the MPPT algorithm, and the monitoring of the DC voltage were successfully implemented in the DSC. © (2014) Trans Tech Publications, Switzerland.

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