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Prem Anand T.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Chellaram C.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Felicia Shanthini C.,Madras Christian College
International Journal of Pharma and Bio Sciences | Year: 2011

The need for the development of new antibiotics to counter drug resistance in bacterial pathogens has been stressed by various researchers worldwide. As the discovery of novel chemical classes have been in decline for the past two decades, the need to exploit new resources in search for effective chemicals with novel mechanism of actions is imperative. Marine bacteria are such a resource yet to be tapped, and the potential it offers is vast. The principal objective of this present investigation was to isolate and screen marine bacteria for the production of bioactive metabolites. Associated bacterial strains were isolated from 10 species of sponges, 12 species of algae, 4 species of crabs, 3 species of ascidians, sediment, one species each of sea cucumber, sea urchin and jellyfish. Gut microflora was isolated from 3 species of mollusc, biofilm bacteria from dead corals and dead oyster shell and egg bacterial symbionts from crab eggs and eggs of molluscs. A total of 633 strains were isolated during a period of two years. In the antibiotic production test 170 strains were found to be active against the five human pathogens (E.coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillis substilis and Candida albicans).In the genus level identification of the potential strains, Alteromonas sp. was found to be the dominant antibiotic producer.


Prem Anand T.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Chellaram C.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Kumaran S.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Felicia Shanthini C.,Madras Christian College
International Journal of Pharma and Bio Sciences | Year: 2011

The need for the development of new antibiotics to counter drug resistance in bacterial pathogens has been stressed by various researchers worldwide. As the discovery of novel chemical classes have been in decline for the past two decades, the need to exploit new resources in search for effective chemicals with novel mechanism of actions is imperative. Marine bacteria are such a resource yet to be tapped, and the potential it offers is vast. Aquaculture has developed into a prime industry to tap the enormous turnover of bio-energy for the benefit of mankind. Since aquaculture depends on self-renewable natural resources, it has infinite future for hundreds of years to come. Aquaculture is also being viewed as the only alternative to augment fish production due to over exploitation of natural fish resources. In this present study a total of 633 marine bacterial strains were isolated. In the initial antibiotic production test using E.coli, 170 strains were found to be antibiotic producers and out of which 101 strains were found to be active against 3 major fish pathogens namely Vibrio harveyi, V. parahaemolyticus, Aeromonas hydrophilla. In the genus level identification of the potential strains the genus Alteromonas sp. dominated followed by Streptomyces sp., Vibrio sp., Bacillus sp., Flavobacterium sp. and Pseudomonas sp.


Prem Anand T.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Chellaram C.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Mark Praveen M.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College | Felicia Shanthini C.,Vel Technology Multi Technology Dr Rangarajan Dr Sakuthala Engineering College
International Journal of ChemTech Research | Year: 2014

Three species of saltmarsh plants ((Salicornia brachiata, Sesuvium portulacastrum, Suaeda maritima) were screened for herbicidal and growth promoter activities using Lemna Bioassay. Two solvents, hexane and methanol were used for the preparation of crude extracts. Three concentrations (500, 100, and 50 ppm) and a control were tested in duplicates for the analysis. The results were obtained on the 3rd and 7th day of the experiment. Of the two solvents used, the methanol extract of all the three saltmarsh plants exhibited herbicidal activity and in the hexane extracts only Salicornia brachiata and Sesuvium portulacastrum at 500ppm concentration exhibited herbicidal activity. The hexane extract of Salicornia brachiate and Suaeda maritima showed growth promoter activity enhancing the growth of the Lemna plants.

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