Veer Kunwar Singh University
Ara, India

Admerit College, Patna named after the well known national hero and legendary freedom fighter Veer Kunwar Singh, is a public university in the regional city of Arrah in the state of Bihar, India. It was established by the Bihar University Act 1976. It serves the education needs of more than one crore population of these districts through its 20 postgraduate departments, 17 constituent degree colleges, three law colleges and 37 affiliated degree colleges. Wikipedia.

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PubMed | Armed Forces Medical College, Base Hospital, Indian Naval Hospital Ship and Veer Kunwar Singh University
Type: Journal Article | Journal: Industrial psychiatry journal | Year: 2015

The relationship between depression, hippocampus (HC), and executive dysfunctions seems complex and has been the focus of research. Recent evidence indicates a possible role of HC in executive dysfunction seen in depression. No such studies on Indian population have been done.To look for changes in HC and executive functions in depression.A cross-sectional analytical controlled study. Sample size 50 (controls 50).Hippocampal volume and executive dysfunction was measured using structural magnetic resonance imaging (MRI) and Wisconsin Card Sorting Test (WCST), respectively. Findings on these two parameters were compared between depressives and healthy matched controls as well as between first episode (FE) and recurrent depressives and across the severity of depression (mild, moderate, and severe).Statistical Package for Social Sciences (SPSS) version 17 was used for analysis. Normally distributed continuous variables were analyzed with independent t-tests. Analysis of variance (ANOVA) was used for multiple comparisons. Categorical data were compared with (2) or Fishers exact test. Clinical correlations were conducted using Pearson correlations.Depressed patients had a smaller left (Lt) hippocampal volume as well as poor performance on several measures of executive functions. Smaller hippocampal volume was found even in FE. Those who had a past burden of depressive illness had an even smaller hippocampal volume. No direct correlation was found between the HC volume and cognitive dysfunction.Depressive illness appears to be toxic to the HC. The relationship between HC and executive dysfunction in depression may be indirect through its functional connections.

Siingh D.,Indian Institute of Tropical Meteorology | Siingh D.,Danish National Space Center | Singh R.P.,Veer Kunwar Singh University
Pramana - Journal of Physics | Year: 2010

In this paper, we have provided an overview of cosmic ray effects on terrestrial processes such as electrical properties, global electric circuit, lightning, cloud formation, cloud coverage, atmospheric temperature, space weather phenomena, climate, etc. It is suggested that cosmic rays control short-term and long-term variations in climate. There are many basic phenomena which need further study and require new and long-term data set. Some of these have been pointed out. © Indian Academy of Sciences.

Khan S.,Military Hospital | Shagufta K.,Veer Kunwar Singh University
Indian Journal of Psychiatry | Year: 2014

A young lady presents to the psychiatry out-patient department with depressive symptoms. Evaluation revealed long standing stressor in the form of a foul odor emanating from her body and over a period of time resulting in social withdrawal and depression with significant impairment of day-to-day functioning. A diagnosis of trimethylaminurea (fish odor syndrome) and adjustment disorder was arrived at. Careful empathetic handling with psychoeducation, behavioral and cognitive counseling and a short course of antidepressants helped her improve significantly with return to almost normal functioning.

Mishra D.,Central Council for Research in Ayurveda | Singh R.K.,Veer Kunwar Singh University | Srivastava R.K.,Narendra Dev University of Agriculture and Technology
Research Journal of Medicinal Plant | Year: 2012

The present study was undertaken to collect information from local folks, tribes and traditional healers on medicinal plants and their uses and the types of diseases treated in tarai regions mainly districts viz., Bahraich and Shrawasti of Uttar Pradesh during August 2007 to March 2010. The indigenous knowledge was gathered through interactions and questioners with tribal rural and traditional healers. The study provides information on 68 plant species belonging to 41 families, Apocynaceae and moraceae contributed maximum species. The various ethno medicinal plants parts used. against the diseases like bronchitis, cardiovascular diseases, diabetes, gastro intestinal disorder, gynaecological disorder, jaundice, neurological diseases, ophthalmic infection, piles, skeletal diseases, skin diseases and snakebite were bark, flowers, rhizomes, roots, leaves, seeds, gum and sometimes whole plants. Inspite of the modernization process, the rural folk and the tribal of the districts still hold on their traditional faith and depend on indigenous plants for their various needs, especially medicines. Since, there is insensitivity among the youngers for this wealth of knowledge, this will be dwindling soon. © 2012 Academic Journals Inc.

PubMed | d Zoological Survey of India, Amity University, Sher-e-Kashmir University of Agricultural Sciences and Technology, Wildlife Institute of India and Veer Kunwar Singh University
Type: | Journal: Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis | Year: 2016

The Hangul (Cervus elaphus hanglu) is a Least Concern deer species, and it is the only survivor of the Red Deer group in the Indian subcontinent. The phylogenetic status of the Hangul relative to the other members of the family Cervidae is not known because sequence data are not available in public databases. Therefore, this study was carried out to determine the phylogenetic status and delineate the genetic boundaries of the Hangul with respect to the other Red Deer subspecies on the basis of cytochrome b gene sequence data (ca 421bp). There are three major monophyletic groups of the Red Deer in the phylogenetic tree, which are referred to as the western (Hap-01 to Hap-10), eastern (Hap-11 to Hap-20) and tarim (Hap-21 to Hap-25) groups. The overall haplotype diversity and per-site nucleotide diversity were 0.9771 (0.0523) and 0.0388 (0.00261), respectively. In the phylogenetic tree, the Hangul clustered with the tarim group (Yarkand and Bactrian Red Deer) with a strong bootstrap support (92%) and was found to be genetically closer to the Bactrian Red Deer than to the Yarkand Red Deer. Our molecular analysis supported the idea that the Hangul diverged from the Bactrian Red Deer and migrated to India from Tajikistan approximately 1.2 MYA.

Paul S.,Kalyani University | Pramanick K.,Kalyani University | Kundu S.,Kalyani University | Kumar D.,Veer Kunwar Singh University | Mukherjee D.,Kalyani University
Molecular and Cellular Endocrinology | Year: 2010

Regulation of ovarian steroidogenesis in vitro by recombinant human insulin-like growth factor-I (IGF-I) and bovine insulin (b-insulin) was investigated in intact follicles and isolated follicular cells of carp, Cyprinus carpio at vitellogenic stage of oocyte maturation. In intact follicles, IGF-I and b-insulin stimulated testosterone and 17β-estradiol production in vitro. In isolated theca cells, IGF-I and b-insulin stimulated testosterone production, whereas in granulosa cells, they stimulated 17β-estradiol production when testosterone was added in the incubation medium as precursor substrate. In intact follicles and in theca cells, IGF-I and b-insulin had no effect on HCG-stimulated testosterone production. HCG-stimulated 17β-estradiol production, however, was significantly increased by IGF-I and b-insulin. To clarify the mechanism of 17β-estradiol production by the ovarian follicles during vitellogenic stage of carp, effects of IGF-I and b-insulin either alone or in combination with HCG on aromatase activity (conversion of testosterone to 17β-estradiol) and cytochrome P450 aromatase (P450arom) gene expression were investigated in vitro. IGF-I and b-insulin alone stimulated aromatase activity and P450arom gene expression and significantly enhanced HCG-induced enzyme activity and P450arom gene expression. Our results thus indicate that IGF-I and b-insulin alone can stimulate testosterone and 17β-estradiol production in vitellogenic follicles of C. carpio by stimulating aromatase activity and P450arom gene expression. Evidence also provided for the modulation of HCG-induced aromatase activity and P450arom gene expression by IGF-I and b-insulin in such follicles. © 2009 Elsevier Ireland Ltd. All rights reserved.

Kumar R.,Veer Kunwar Singh University | Tiwary R.K.,Veer Kunwar Singh University
Cytologia | Year: 2014

The seeds of Eclipta alba have been successfully employed with different doses of X-ray irradiation to assess its effect on somatic chromosomes. The data obtained from the experimentally treated material have further been analysed with all the implications to understand the effects of radiation on the chromosome structure, behaviour and gene mutation. Although irradiation is known to induce chromosomal aberrations and mutation in many plants, its effect on Eclipta alba is not known. Data were obtained with regards to survival of seedlings and induced chromosomal anomalies in root tip cells. It may also be safely stated that experimental induction by physical means (X-rays) holds a clue to understanding the gene mutation and also the adaptability of the species in different environmental conditions. The result of experimental manipulation done as a part of the present investigation strengthens the contention that Eclipta alba in general is highly plastic and capable of forming populations through the adjustment of their genetic system. ©2014 The Japan Mendel Society.

Shekhar H.,Veer Kunwar Singh University | Kant V.,Veer Kunwar Singh University
Asian Journal of Chemistry | Year: 2013

The study reports the thermal and growth investigation of binary alloys represented by nicotinamide with b-naphthol. The solid-liquid equilibrium data determined by Thaw-melt method with their corresponding compositions construct the solid-liquid phase diagram which suggests simple eutectic behaviour is followed by the binary system. The activity coefficient model based on enthalpy of fusion was employed to calculate the excess thermodynamic properties that of gE, hE and sE, which predict the nature of molecular interaction, ordering and stability between the components. The partial and integral mixing functions ΔGM, ΔH M, ΔSM of the eutectic and noneutectic alloys were also computed. The driving force of nucleation during solidification (ΔGv), critical size or radius (r*) and the critical free energy of nucleation (ΔG*) at different undercoolings have been determined. Using heat of fusion data the solid-liquid interface energy (σ), grain boundary energy (σgb), the Gibbs-Thomson coefficient (τ) and roughness parameter (α) of all the alloys are evaluated by numerical method. Interface morphology of the alloys follows the Jackson's surface roughness (α) theory and predicts the faceted growth proceeds in all the alloys.

PubMed | Wildlife Institute of India and Veer Kunwar Singh University
Type: | Journal: Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis | Year: 2016

Swamp deer (Rucervus duvaucelii) is an endemic, Scheduled I species under the Wildlife (Protection) Act 1972, India. According to variations in antler size, it has been classified into three subspecies, namely Western (R. duvaucelii duvaucelii), Central (R. duvaucelii branderi), and Eastern (R. duvaucelii ranjitsinhii). For planning effective ex situ and in situ conservation of a wide-ranging species in different bioclimatic regions and in wildlife forensic, the use of genetic characterization in defining morpho/ecotypes has been suggested because of the geographic clines and reproductive isolation. In spite of these morphotypes, very little is known about the genetic characteristics of the three subspecies, hence no strict subspecies-based breeding plan for retaining the evolutionary characteristics in captive populations for subsequent re-introduction is available except for a few studies. We describe the genetic characteristics of these three subspecies using cytochrome b of the mtDNA genome (400bp). The DNA sequence data indicated 11 variable sites within the three subspecies. Two paraphyletic clades, namely the Central India and Western-Eastern populations were found, whereas the Western and Eastern populations are monophyletic with a bootstrap value of 69% within the clade. We suggest the need of sorting these three subspecies using different molecular mtDNA markers in zoos for captive breeding purposes so as to retain the genetic diversity of the separate geographic clines and to use a subspecies-specific fixed-state nucleotide to assess the extent of poaching to avoid any population demography stochastically in India.

PubMed | a Molecular Systematic Laboratory, Wildlife Institute of India and Veer Kunwar Singh University
Type: | Journal: Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis | Year: 2016

Monitor lizards are Varanus species widely distributed, endangered reptile in the IUCN red data list. In India, based on the morphological and ecological characteristic, it is divided into four species viz. Bengal monitor lizard, Yellow monitor lizard, Desert monitor lizard and Water monitor lizard. These four species listed as Schedule I species in Indian Wildlife (Protection) Act 1972. This paper first attempt to present Forensically Informative Nucleotide Sequencing (FINS) for the Indian Varanus based on three mitochondrial genes. The molecular framework will be useful for the identification of Indian Varanus species and trade products derived from monitors and as such, have important applications for wildlife management and conservation. Here, we used known 14 individual skin pieces of four species of monitor lizards; the partial fragment of three mitochondrial genes (Cyt b, 12S rRNA, and 16S rRNA) were amplified for genetic study. In Cyt b, 12S rRNA and 16s rRNA, we observed, 5, 5 and 4 Haplotypes; 71, 69, and 43 Variables sites; 90, 89, and 50 Parsimony Informative sites within four species of Indian monitor lizards, respectively. Despite it, the nucleotide composition was T 26.4, C 32.8, A 29.2 and G11.6; T 18.8, C 29.7, A 34.0 and G 17.5; T 21.7, C 27.3, A 32.5 and G 18.5 in Cyt b, 12S rRNA and 16S rRNA, respectively. The neighbor joining phylogenetic tree and maximum parsimony tree of three mitochondrial genes, showed similar results and reveal that, there are two major clades are present in Indian monitor lizards.

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