VCSG Government Medical science and Research Institute

Srīnagar, India

VCSG Government Medical science and Research Institute

Srīnagar, India
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Deepak D.,VCSG Government Medical science and Research Institute | Sinha A.N.,VCSG Government Medical science and Research Institute | Gusain V.S.,VCSG Government Medical science and Research Institute | Goel A.,SRMS Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2012

Objective: Meditation has long been known to affect human physiology through autonomic nervous system. This study was designed to assess sympathetic autonomic functional status of meditators of various age groups. Material and Methods: Three clinical tests, Isometric handgrip test,Cold pressor test and Valsalva Meneuver were studied in 25 meditators of age ranging from 25 to 75 years. The results were compared with those observed in 25 non-meditators of matching age and socio economic status. Observation and Results: The basal cardiac parameters viz heart rate and blood pressure were uniformly lower in meditators than non meditators in all age groups, more so in senior meditators. On performing isometric handgrip test, non-meditators developed significant increase in blood pressure and heart rate during gripping than that seen in meditators. In cold pressor test, as compared to non-meditators, mediators showed blunted increase in blood pressure along with returning of blood pressure to basal level earlier, which indicated presence of controlled sympathetic drive in meditators. In Valsalva maneuver the overshoot of BP was lower in meditators than in non meditators. Conclusion: It can be concluded that the regular practice of meditation initially blunted the sympathetic drive and later on developed control over sympathetic function of meditators.


Garg R.,VCSG Government Medical science and Research Institute | Goyal S.,Uttrakhand Dental Clinic | Gupta S.,Mahatma Gandhi Institute
Maternal and Child Health Journal | Year: 2012

The onset of menstruation is one of the most important physiological changes occurring among girls during the adolescent years. Menstruation heralds the onset of physiological maturity in girls. It becomes the part and parcel of their lives until menopause. Apart from personal importance, this phenomenon also has social significance. In India, menstruation is surrounded by myths and misconceptions with a long list of "do's" and "don'ts" for women. Hygiene-related practices of women during menstruation are of considerable importance, as it may increase vulnerability to Reproductive Tract Infections (RTI's). Poor menstrual hygiene is one of the major reasons for the high prevalence of RTIs in the country and contributes significantly to female morbidity. Most of the adolescent girls in villages use rags and old clothes during menstruation, increasing susceptibility to RTI's. Adolescents constitute one-fifths of India's population and yet their sexual health needs remain largely unaddressed in the national welfare programs. Poor menstrual hygiene in developing countries has been an insufficiently acknowledged problem. In June 2010, the Government of India proposed a new scheme towards menstrual hygiene by a provision of subsidized sanitary napkins to rural adolescent girls. But there are various other issues like awareness, availability and quality of napkins, regular supply, privacy, water supply, disposal of napkins, reproductive health education and family support which needs simultaneous attention for promotion of menstrual hygiene. The current article looks at the issue of menstrual hygiene not only from the health point of view, but also considers social and human rights values attached to it. © Springer Science+Business Media, LLC 2012.


Mukherjee S.,VCSG Government Medical Science and Research Institute | Gogoi J.B.,VCSG Government Medical Science and Research Institute
Current Chemical Biology | Year: 2011

Free radicals and oxidants play a dual role as both toxic and beneficial compounds, which in low/moderate concentrations are involved in normal physiological functions but excess production of free radicals or decrease in antioxidant level leads to oxidant stress. Free radicals are produced either from normal cell metabolisms in situ or from different external sources (pollution, cigarette smoke, radiation, medication etc). When an overload of free radicals cannot gradually be destroyed, their accumulation in the body is a harmful process that can mediate damage to cellular structures, including lipids, proteins, RNA and DNA leading to a number of diseases. ROS (reactive oxygen species) and RNS (reactive nitrogen species) in excess can damage biological processes, and this situation has been observed in various acute and chronic diseases such as cancer, autoimmune disorders, aging, cataract, cardiovascular and neurodegenerative diseases. This review deals in depth with the role of free radical generation, the mechanisms of formation and catabolism, and the role in various diseases and the function of different phytoconstituents as a defensive factor in the treatment of diseases caused by free radicals, as in the new era they are conferring less side effects and are compatible to body physiology. © 2011 Bentham Science Publishers.


Pathania M.,VCSG Government Medical science and Research Institute
BMJ case reports | Year: 2013

The clinical presentation of an adolescent man with left lung hypoplasia is described in detail including the history and clinical examination findings. On further investigation, the chest x-ray and CT scan of the chest reveal interesting findings. Generally, such conditions are brought to notice in the early years of life but the presentation of this condition at the age of 18 years make it even more interesting and unique. This is a discussion of the management of such a patient and the different types of lung hypoplasia which can be encountered in clinical practice.


Upadhyaya S.K.,VCSG Government Medical Science and Research Institute | Raina R.S.,VCSG Government Medical Science and Research Institute | Sharma A.,VCSG Government Medical Science and Research Institute | Thawani V.,VCSG Government Medical Science and Research Institute | Dimari D.,VCSG Government Medical Science and Research Institute
Journal of Pharmacology and Pharmacotherapeutics | Year: 2012

Carbamazepine (CBZ) is frequently used for epilepsy and variouspsychiatric illnesses. It is known for its dermatological side effects which may range from mild rash to life-threatening reactions as Stevens Johnson syndrome or toxic epidermal necrolysis. We hereby report a rare case of 17-year-old woman suffering from generalized tonic clonic epilepsy with comorbid bipolar affective disorder, who was initially treated with sodium valproate with partial improvement. After 19 days of addition of CBZ to the therapy, the patient developed erythema multiforme major with >60% skin involvement and oral, conjunctival, intestinal, and vaginal mucosal involvement.


Pathania M.,VCSG Government Medical science and Research Institute
BMJ case reports | Year: 2013

A pregnant woman, in her early 20s, presents with chorea following an emotional outburst. While the family members feel it to be a spirit haunting her, we try to establish the medical diagnosis of the present condition. There is a history of rheumatic fever in the past and examination reveals choreioathetoid jerky movements of her upper limbs with jerky speech, spooning of her limbs and demonstration of milkmaid's grip. Laboratory investigations did not reveal anything interesting. We discuss the diagnosis and management of this patient.


Joshi A.K.,Vcsg Government Medical Science And Research Institute | Joshi C.,Vcsg Government Medical Science And Research Institute | Singh S.,I.M.S | Singh V.,Vcsg Government Medical Science And Research Institute
Foot | Year: 2012

Background: Traumatic loss of talus during a compound injury of ankle is an unusual injury. Objective: We report a 55 years old woman who sustained an open ankle injury with complete extrusion of talus and loss at the injury site. Method: A tricortical bone graft was obtained from iliac crest and talar dimensions carved with 5. cm length and 3. cm height given by buttressing fibular graft between them. These grafts are made in the shape of talus by fixing them together with cortical screw and binding them together with Ethibond No. 5. By anterior approach ankle was opened and talar graft was placed in between the raw surfaces of tibia and calcaneus to facilitate ankle arthrodesis. Result: Patient had solid fusion at the ankle joint after 4 months with no pain on walking. Conclusion: The definitive treatment of this serious lower extremity injury remains controversial we have attempted this novel way of treatment as the patient was unable to afford talar prosthesis and facilities of allogenic bone grafts were not there. © 2012 Elsevier Ltd.


Pathania M.,VCSG Government Medical science and Research Institute | Lali B.S.,VCSG Government Medical science and Research Institute | Rathaur V.K.,VCSG Government Medical science and Research Institute
BMJ Case Reports | Year: 2013

The clinical presentation of an adolescent man with left lung hypoplasia is described in detail including the history and clinical examination findings. On further investigation, the chest x-ray and CT scan of the chest reveal interesting findings. Generally, such conditions are brought to notice in the early years of life but the presentation of this condition at the age of 18 years make it even more interesting and unique. This is a discussion of the management of such a patient and the different types of lung hypoplasia which can be encountered in clinical practice. Copyright 2013 BMJ Publishing Group. All rights reserved.


PubMed | VCSG Government Medical science and Research Institute
Type: | Journal: BMJ case reports | Year: 2013

The clinical presentation of an adolescent man with left lung hypoplasia is described in detail including the history and clinical examination findings. On further investigation, the chest x-ray and CT scan of the chest reveal interesting findings. Generally, such conditions are brought to notice in the early years of life but the presentation of this condition at the age of 18 years make it even more interesting and unique. This is a discussion of the management of such a patient and the different types of lung hypoplasia which can be encountered in clinical practice.


Sinha A.N.,VCSG Government Medical science and Research Institute | Deepak D.,VCSG Government Medical science and Research Institute | Gusain V.S.,VCSG Government Medical science and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2013

Background and Aim: Pranayama, the art of breath control, is considered to be the heart of yogic exercises. The present study was performed with the aim of evaluating the effect of Pranayama/Alternate Nostril Breathing (A.N.B.) on the parasympathetic nervous system in healthy young adult males. Methods: A comparative account of the expiratioin: inspiration ratio (E:I ratio) and the orthostatic tolerance test (30:15 ratio) at the basal level, at the start of the study and after the practice of A.N.B for 5 minutes and following a training period of 6 weeks. Result and Conclusion: This study showed that the parasympathetic tone was enhanced appreciably in the participants. The observations of this study suggest that the yogic exercise of A.N.B. influences the parasympathetic nervous system significantly.

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