Mountain View, CA, United States
Mountain View, CA, United States

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Patent
Vascular Dynamics | Date: 2017-01-30

Apparatus and methods are described, including identifying a subject as suffering from hypertension. In response to the identifying (a) a radius of curvature of a first set of at least three regions of an arterial wall of the subject is increased at a given longitudinal location, while (b) allowing the first set of regions of the arterial wall to pulsate. A device is implanted inside the artery at the longitudinal location such that the device applies pressure to the arterial wall at a second set of at least three regions of the artery, but does not contact the first set of regions, the first set regions and the second set of regions alternating with each other. Other embodiments are also described.


Patent
Vascular Dynamics | Date: 2013-11-27

Apparatus and methods are described, including identifying a subject as suffering from hypertension. In response to the identifying (a) a radius of curvature of a first set of at least three regions of an arterial wall of the subject is increased at a given longitudinal location, while (b) allowing the first set of regions of the arterial wall to pulsate. A device is implanted inside the artery at the longitudinal location such that the device applies pressure to the arterial wall at a second set of at least three regions of the artery, but does not contact the first set of regions, the first set of regions and the second set of regions alternating with each other. Other embodiments are also described.


Patent
Vascular Dynamics | Date: 2015-10-23

An implantable frame comprises a plurality of corner structures configured to decrease pressure to the vessel wall and define pulsatility enhancing windows of the implantable frame. The corner structures may comprise plurality of neighboring longitudinal struts that extend in a longitudinal direction of the blood vessel when placed to form the vessel wall to a substantially polygonal cross-section and distribute pressure loading of the corner structure among the plurality of neighboring longitudinal struts to improve biocompatibility. The corner structures also allow increased forming of the vessel wall and can provide stretching of the vessel wall to enhance pulsatility of the vessel wall.


Patent
Vascular Dynamics | Date: 2011-02-18

Apparatus and methods are described including an implantable device shaped to define (a) at least two artery-contact regions, the artery-contact regions comprising struts that are configured to stretch an arterial wall by applying pressure to the arterial wall, and (b) at least two crimping regions that comprise locking mechanisms configured to prevent the crimping regions from becoming crimped due to pressure from the wall of the artery on the artery-contact regions. The crimping regions are configured to be crimped during insertion of the device, via a catheter, by the locking mechanisms being unlocked during insertion of the device. Other embodiments are also described.


Stimulation of a stretch receptor response to the cardiac cycle is enhanced by constraining a region of a blood vessel wall upstream and/or downstream of a baroreceptor. The constraint may be external or internal and will typically be effected using a circumferential restraint placed over or within the blood vessel.


Patent
Vascular Dynamics | Date: 2012-04-24

Apparatus and methods are described including an implantable device having first and second longitudinal ends, the device having a length of less than 80 mm when the device is unconstrained. The device includes struts arranged such that, when the device is unconstrained, along a continuous portion of the device having a length that is at least 5 mm, a maximum inter-strut distance defined by any set of two adjacent struts is more than 1.5 times as great as a maximum inter-strut distance defined by any set of two adjacent struts within longitudinal portions of the device within 3 mm of the longitudinal ends of the device. Other applications are also described.


Patent
Vascular Dynamics | Date: 2010-05-05

Apparatus and methods are described, including identifying a subject as suffering from hypertension. In response to the identifying (a) a radius of curvature of a first set of at least three regions of an arterial wall of the subject is increased at a given longitudinal location, while (b) allowing the first set of regions of the arterial wall to pulsate. A device is implanted inside the artery at the longitudinal location such that the device applies pressure to the arterial wall at a second set of at least three regions of the artery, but does not contact the first set of regions, the first set of regions and the second set of regions alternating with each other. Other embodiments are also described.


Patent
Vascular Dynamics | Date: 2014-12-04

Apparatus is provided for treating hypertension of a subject. The apparatus includes an implantable element which has a non-circular shape and which is configured to reduce the hypertension by facilitating an assumption of a non-circular shape by a blood vessel in a vicinity of a baroreceptor of the subject, during diastole of the subject. Other embodiments are also described.


Patent
Vascular Dynamics | Date: 2015-07-28

Apparatus and methods are described including an implantable device shaped to define (a) at least two artery-contact regions, the artery-contact regions comprising struts that are configured to stretch an arterial wall by applying pressure to the arterial wall, and (b) at least two crimping regions that comprise locking mechanisms configured to prevent the crimping regions from becoming crimped due to pressure from the wall of the artery on the artery-contact regions. The crimping regions are configured to be crimped during insertion of the device, via a catheter, by the locking mechanisms being unlocked during insertion of the device. Other embodiments are also described.


News Article | February 17, 2015
Site: www.fiercemedicaldevices.com

Rainbow Medical will open an office in Shanghai to help facilitate strategic deals as part of a $25 million cash infusion from investors in China. The firm is an Israeli-based seed investor and incubator specifically for medical device and medical technology startups. The new investors are in good company; in recent years Medtronic ($MDT), Abbott Laboratories ($ABT), the Sorin Group and Sony ($SNE) have all put money into Rainbow Medical. "We opened the office in Shanghai to capitalize on China's fast-growing market for our products and to foster collaborations with Chinese medical device companies," Efi Cohen-Arazi, co-founder and CEO of Rainbow Medical, said in a statement. "There is a strong demand in the fast-growing Chinese healthcare industry for Rainbow Medical's breakthrough technologies." Investors in the latest fundraising include China's largest private insurance holding company Ping An, investment and financial management company YongJin, the Chinese telecommunications company ZTE and undisclosed Chinese venture capital funds. Rainbow Medical will invest the new funds into seeding new startups based upon the intellectual property that it holds, as well as to fund its existing portfolio companies. The firm was founded in 2003 by GlenRock Israel, a private equity group specializing in technology and the life sciences owned by Israeli businessman Leon Recanati. It was co-founded by medical device entrepreneur Yossi Gross and Cohen-Arazi. Rainbow Medical has a portfolio of 12 medical device startups that address a range of chronic indications such as heart disease, diabetes, hypertension, blindness, uterine fibroids and chronic neuropathic pain. In January, Vascular Dynamics secured the first $8.4 million tranche of a $16.8 million Series B round to advance its U.S. and European clinical trial program for its resistant hypertension treatment device. The financing was led by HBM Healthcare Investments, joined by existing investors Rainbow Medical, the MedFocus Funds and an undisclosed existing investor with more than $1 billion in assets under management. - here is the release Related Articles: Sony sinks $10M into Israeli medical device incubator Device investment firm gets support from Medtronic, Abbott Nanotech implant to reverse blindness targeted for 2017 How did Israel become a hotbed for medical devices? Sorin commits $5M more to Israeli heart failure device startup, with option to buy Medical devices help spur Israeli VC investment growth

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