Varna, Bulgaria
Varna, Bulgaria

The Technical University of Varna is a state university in Varna, Bulgaria, founded in 1962. Wikipedia.


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Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MSCA-NIGHT-2016 | Award Amount: 171.75K | Year: 2016

FRESH (Find Research Everywhere and SHare) is led by the Center for Research and Analysis with 13 partners and 5 associated partners. The Consortium includes Bulgarias first technological park, a chamber of industry and commerce, a pan-European organisation, leading research organisations, academia, and media. The aim is to create a series of participatory and media events to promote research careers, aimed in particular towards young people and their parents. Building on existing understanding developed through previous local initiatives including Researchers Night, and with reference to Europe-wide research like the Special Eurobarometer 401, as well as the MASIS report and the in-depth Education and Training Monitor 2015 for Bulgaria , the focus of this 20-month programme will be on enhancing the public understanding of and engagement with science. Core activities during the Night will include a digital participatory campaign to engage audiences across the country; international live streaming; science city quests and quizzes; science cafes; hands-on experiments; science shows; simulations; games and competitions. Thematic programmes will include, among other, food and nutrition, inspired by 2016 International Year of Pulses , engineering, oceanology, innovation and business incubators, technological transfer, medicine, and others. The on-the-ground activities will take place in the largest cities including several where Researchers Night has not been marked. Innovation will be an intricate part of the events through the use of online technology to enhance the physical activity, engage particularly young audiences and to guarantee sustainability outside the lifespan of the project. The activities of the first year will allow learning to accrue from a thorough evaluation. The project will strengthen the capabilities of the partners in organising events for a general audience, and for underserved audiences, including girls and people with hearing disabilities.


Grant
Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: Fission-2013-5.1.1 | Award Amount: 1.86M | Year: 2013

Medical exposures for radiological examinations represent the highest and fastest growing contribution to manmade radiation exposure in the EU underlying the need for medical physics experts (MPEs), regulators and scientists in industry to bring in new research results and expertise and to deploy resources in addressing this important issue. The EC recognized the urgency and the EU tender European guidelines for the Medical Physics Expert (MPE) (TREN/H4/1672009) was issued to develop and update the role of MPEs in Europe. The final report has been approved by the EC and includes an agreed mission statement and key activities for MPEs. The new qualification framework defines the MPE as an MP who, through planned advanced training and CPD, achieves the highest level possible (i.e., European Qualifications Level 8) in her/his specialty. However, it is recognized that few Member States have the expertise and facilities to provide the necessary training. A preliminary survey among National Organisations of MP and medical device companies showed that a dedicated training scheme has become a necessity. Three end-users were identified: the hospital MPE, the scientist in industry and regulators assessing exposures in Diagnostic and Interventional Radiology. The EUTEMPE-RX consortium will develop, put into practice and evaluate a new pilot EFTS for the MPE in Diagnostic and Interventional Radiology, which includes both face-to-face and on-line teaching. The aim is to ensure that candidates become knowledgeable about all current issues in radiation safety culture in hospitals and to make the MPE a radiation protection advocate for patients. The course will address the themes identified in the MELODI strategic research agenda, DoreMi and EMAN projects. A business plan will be developed for the sustainability of the network, which would provide a template for the development of similar programmes in the other specialties of medical physics.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-CSA-Infra | Phase: INFRA-2008-1.1.1 | Award Amount: 4.00M | Year: 2009

The recently finished FP6 RI Black Sea SCENE project has established a Black Sea Scientific Network of leading environmental and socio-economic research institutes, universities and NGOs from the countries around the Black Sea and has developed a distributed virtual data and information infrastructure that is populated and maintained by these organisations to improve the identification, access, exchange, quality indication and use of their data and information about the Black Sea. The Black Sea SCENE research infrastructure stimulates scientific cooperation, exchange of knowledge and expertise, and strengthens the regional capacity and performance of marine environmental data and information management, underpins harmonization with European marine data quality control/assessment procedures and adoption of international meta-data standards and data-management practices, providing improved data & information delivery services for the Black Sea region at a European level. The Up-Grade of Black Sea SCENE project aims: a) to extend the existing research infrastructure with 19 marine environmental institutes/organizations from the 6 Black Sea countries, b) to implement the results of the Joint Research Activities of the FP6 RI SeaDataNet project (common communication standards and adapted technologies to ensure the datacenters interoperability), c) to network the existing and new Black Sea datacenters, active in data collection, and provide integrated databases of standardized quality on-line, d) to realize and improve on-line access to in-situ and remote sensing data, meta-data and products and e) to adopt standardized methodologies for data quality checking to ensure the quality, compatibility and coherence of the data issuing from so many sources. The Up-Grade Black Sea SCENE project is undertaken by 51 partners of which 43 are located in the Black Sea countries.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-TP | Phase: HEALTH-2007-1.1-4 | Award Amount: 4.03M | Year: 2009

Our particle-based method allows us to synthesise high complexity peptide arrays by combinatorial synthesis and for an unrivalled prize. We plan to further develop this new technology up to the level of robust prototype machines, and mate it to bioinformatics and readout tools. Together, our procedure(s) should boost the field of proteomics in a similar way as the lithographic technologies did with the field of genomics. Central to our novel method are the activated chemical building blocks that are frozen within solid amino acid particles. Thereby, we can use a colour laser printer to send them to defined addresses on a 2D support, where the particles are simply melted to induce a spatially defined coupling reaction of now freed amino acid derivatives. By repeated printing and melting cycles this simple trick yields high complexity peptide arrays. Based on existing pre-prototypes, we will develop a user-friendly peptide laser printer that spatially defined addresses our 20 different amino acid toners in high resolution to a support (WP1), and a scanner that especially fast and sensitive reads out the large formats delivered by the peptide laser printer (WP2). The increased production of amino acid toners and array supports are other bottlenecks in the output of peptide arrays that are tackled in WP3. This should allow us to increase the output of individual peptide spots from currently 0,5 Million to >10 Million peptides per month. Finally, to foster a market for high complexity peptide arrays, we will work out paradigmatic application examples in WP4. These aim to directly screen for antibiotic or apoptosis inducing D-peptides, and for the comprehensive readout of the different antibodies that patrol the serum of autoimmune patients. Based on user-friendly prototype machines, on first paradigmatic application examples for high complexity peptide arrays, and shielded by a strong patent, the participating SMEs will commercialise this new technology.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: HEALTH.2011.1.1-1 | Award Amount: 5.55M | Year: 2012

We want to further develop our tools and technologies for high-throughput research, with the final goals being (I.) the particle-based combinatorial synthesis of 1 Mio different peptides on a glass slide for chemical costs of ~50 (KIT, CBL, MS, TUV), and (II.) the labelling-free parallel readout of binding affinities by a variant reflectometric interference spectroscopy method for ~10.000 peptide spots per cm(\2) when staining the array with an unlabeled protein (BIA, KIT). These tools provide the basis (III.) for a standardized, fast, and reliable high-throughput procedure that we want to develop in order to find high-affinity peptide binders against any pharmaceutically interesting target protein. Such a procedure might have an important impact in medicine and in the biotechnology industry. In order to achieve this goal, we will use display techniques that in combination with high-throughput sequencing typically will identify ~100.000 putative peptide binders per target protein (ISO). These will be synthesized in array format to validate binding to the target protein by an independent method (PPP, DKFZ). Next, based on binders from initial screens, many variant peptides are synthesized in high-density array format for iterative screens (PPP, DKFZ, KIT), whereby massive parallel labelling-free detection of binders pinpoints higher-affinity binders (BIA). In order to validate our novel high-throughput procedure, (IV.) we want to find high-affinity peptide binders against relevant target proteins (delivered by APO and OXF), and test these binders in biological assays (OXF, APO).


Grant
Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: FP7-2008-PEOPLE-NIGHT | Award Amount: 91.96K | Year: 2008

The RE*CAME project main goal is to enhance public recognition of researchers and their role in society and to encourage young people in Bulgaria to embark on scientific career. It will also raise the awareness on the EU activities related to researchers jobs, services and rights. The following project objectives are defined: to disclose to the public the hidden sides of life and work of researchers, and show them as professionals and at the same time as ordinary people; to raise the public awareness on the contribution of researchers to society, to its progress and development; to highlight the EU emphasis and large support to its researchers and the opportunities for them in the large European labour market; to make science and the respective career attractive for young people. The target audience of the project will be first, young people children, teen-agers and students, and second, their parents and the public at large. RE*CAME will provide various opportunities to Bulgarians to interact and have fun with researchers in 6 Bulgarian cities Sofia, Plovdiv, Stara Zagora, Sliven, Varna region and Rousse: national photo competition among young people on the topic Researchers in motion - targeted at young people; amusement programs Researchers E-Motions Cabinets of curiosity games with the public Live as Researcher; exhibitions of researchers own works and on environmental topics; short movies on researchers in Biology, Chemistry and Ecology, booklet with researchers own verses, exhibitions and newspapers and dedicated web materials on researchers profession and traditions. EU stands Researchers in motion.


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: H2020-TWINN-2015 | Award Amount: 998.05K | Year: 2016

Nowadays, the development of realistic three-dimensional computational and physical models of breast tumours with irregular shapes is an urgent requirement. The availability of such models is a powerful instrument in the hands of engineers, physicians and physicists to be used in the development of new technologies for precise definition of the boundaries of these cancers. Scientists from the biomedical engineering unit at Technical University of Varna are present in this area both at modelling and simulation of computational breast phantoms and x-ray breast imaging techniques. To advance in their research aims and therefore to raise the profile of their researchers and S&T capacity of the host organisation, collaborations with top research institutions from complementary areas of expertise are a requirement. In addition, the touch with world experts in this area is needed in order to have local researchers at host informed about the most current findings in the field and to discuss specific scientific issues that otherwise will not have such a chance. The main objective of this action is to increase the research and innovation capacity of the host organisation in the field of computational modelling of breast tumours (including cancers with irregular shape) and their use in studies of advanced x-ray breast imaging techniques such as breast tomosynthesis and phase contrast imaging. For this purpose, the project will establish a close and sustainable collaboration platform, in the form of a network of three scientific groups working in the specific domain of modelling and simulations dedicated for studies of x-ray breast imaging techniques. The network will aim to (a) increase the research and innovation capacity of the host organisation, (b) integrate results of ongoing research, (c) facilitate progress beyond the actual individual possibilities, (d) advance the research activities of all partners through a joint and mutually fruitful collaboration.


Ivanov V.I.,Varna Technical University
International Journal of Information Technology and Decision Making | Year: 2015

In this paper, we obtain second- and first-order optimality conditions of Kuhn-Tucker type and Fritz John one for weak efficiency in the vector problem with inequality constraints. In the necessary conditions, we suppose that the objective function and the active constraints are continuously differentiable. We introduce notions of KTSP-invex problem and second-order KTSP-invex one. We obtain that the vector problem is (second-order) KTSP-invex if and only if for every triple $(\bar{x},\bar{\lambda},\bar{\mu})$ with Lagrange multipliers $\bar{\lambda}$ and $\bar{\mu}$ for the objective function and constraints, respectively, which satisfies the (second-order) necessary optimality conditions, the pair $(\bar{x},\bar{\mu})$ is a saddle point of the scalar Lagrange function with a fixed multiplier $\bar{\lambda}$. We introduce notions second-order KT-pseudoinvex-I, second-order KT-pseudoinvex-II, second-order KT-invex problems. We prove that every second-order Kuhn-Tucker stationary point is a weak global Pareto minimizer (global Pareto minimizer) if and only if the problem is second-order KT-pseudoinvex-I (KT-pseudoinvex-II). It is derived that every second-order Kuhn-Tucker stationary point is a global solution of the weighting problem if and only if the vector problem is second-order KT-invex. © 2015 World Scientific Publishing Company.


Ivanov V.I.,Varna Technical University
Journal of Global Optimization | Year: 2011

Anewnotion of a second-orderKT invex problem(P)with inequality constraints is introduced in this paper. This class of problems strictly includes the KT invex ones. Some properties of the second-order KT invex problems are presented. For example, (P) is second-order KT invex if and only if each point, which satisfies the second-order Kuhn-Tucker necessary optimality conditions, is a global minimizer. A problem with quasiconvex data is(second-order) KT invex if and only if it is (second-order) KT pseudoconvex. © Springer Science+Business Media, LLC. 2010.


Grant
Agency: European Commission | Branch: FP7 | Program: MC-CIG | Phase: FP7-PEOPLE-2011-CIG | Award Amount: 100.00K | Year: 2012

Breast cancer remains the most common cause of death for women below seventy years of age. In Europe, one in ten women will develop breast cancer in her lifetime. Early diagnosis is recognised as a critical factor that can improve the chance of survival. X-ray mammography is currently considered best practice for screening and early diagnosis of breast carcinoma. However, a significant number of breast cancers remain undetected when using conventional 2D mammography imaging, due to insufficient soft tissue contrast and the effect of overlying anatomical structures. A method that combines the advantages of the phase contrast imaging and digital breast tomosynthesis may result in high contrast tomograms with well outlined breast cancer margins. This project will aim to develop, test and validate a three-dimensional reconstruction algorithm for phase contrast digital breast tomosynthesis. The overall objective will be pursued through the following specific objectives that will be addressed in a number of highly innovative tasks of design, modelling, numerical simulations and experimental work: (a) Development of a simulation tool for generation of phase contrast images over limited angular range; (b) Development of a three-dimensional algorithm for phase contrast breast tomosynthesis; (c) Validation and further refinement of the algorithm with computer models of ground truth phantoms as well with physical phantoms that will be exploited at laboratory environment. The availability of three-dimensional reconstruction algorithms dedicated for phase contrast breast tomosynthesis will provide a possibility to study the potential of this novel technique to enhance contours of different breast soft tissues, thus resulting in clearly visible three dimensional soft tissue morphology.

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